adisease

Showing entry for Brucellosis

General Disease Information
BXGD Id	BXGD000392
Disease Name	Brucellosis
Disease CUI Id	C0006309
MeSH Codes	C01
Disease Class Name	Infections
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:0050117
Disease Ontology Class Name	disease by infectious agent
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O15118	BXGT004127	NPC intracellular cholesterol transporter 1	4864	reviewed	Transporter
O15553	BXGT004181	Pyrin	4210	reviewed
O60260	BXGT004864	E3 ubiquitin-protein ligase parkin	5071	reviewed	Enzyme
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P08195	BXGT006745	4F2 cell-surface antigen heavy chain	6520	reviewed	Transporter
P14151	BXGT007990	L-selectin	6402	reviewed
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16581	BXGT008245	E-selectin	6401	reviewed
P19429	BXGT008479	Troponin I, cardiac muscle	7137	reviewed	Cellular structure
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P20339	BXGT008565	Ras-related protein Rab-5A	5868	reviewed
P21579	BXGT008665	Synaptotagmin-1	6857	reviewed	Transporter
P21580	BXGT008666	Tumor necrosis factor alpha-induced protein 3	7128	reviewed	Enzyme
P21796	BXGT008690	Voltage-dependent anion-selective channel protein 1	7416	reviewed
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P27352	BXGT009174	Cobalamin binding intrinsic factor	2694	reviewed
P27815	BXGT009208	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	5141	reviewed
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P30044	BXGT009395	Peroxiredoxin-5, mitochondrial	25824	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35610	BXGT009855	Sterol O-acyltransferase 1	6646	reviewed	Enzyme
P35858	BXGT009876	Insulin-like growth factor-binding protein complex acid labile subunit	3483	reviewed	Receptor
P40926	BXGT010207	Malate dehydrogenase, mitochondrial	4191	reviewed	Enzyme
P40933	BXGT010209	Interleukin-15	3600	reviewed
P46934	BXGT010553	E3 ubiquitin-protein ligase NEDD4	4734	reviewed	Enzyme
P49747	BXGT010732	Cartilage oligomeric matrix protein	1311	reviewed
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P81172	BXGT011935	Hepcidin	57817	reviewed
Q04206	BXGT012754	Transcription factor p65	5970	reviewed	Transcription factor
Q13478	BXGT013362	Interleukin-18 receptor 1	8809	reviewed	Receptor
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14653	BXGT013494	Interferon regulatory factor 3	3661	reviewed	Transcription factor
Q16637	BXGT013646	Survival motor neuron protein	6607	reviewed	Epigenetic regulator
Q8IVL6	BXGT018347	Prolyl 3-hydroxylase 3	10536	reviewed	Extracellular structure
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q9H4A3	BXGT020473	Serine/threonine-protein kinase WNK1	65125	reviewed	Kinase
Q9NR12	BXGT021174	PDZ and LIM domain protein 7	9260	reviewed	Cellular structure
Q9UBZ9	BXGT021666	DNA repair protein REV1	51455	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y646	BXGT022317	Carboxypeptidase Q	10404	reviewed	Enzyme
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q96QC4	BXGT023878	MHC class I polypeptide-related sequence A	100507436	unreviewed
Q9BQQ3	BXGT024065	Golgi reassembly-stacking protein 1	64689	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}