adisease

Showing entry for Contracture

General Disease Information
BXGD Id	BXGD000635
Disease Name	Contracture
Disease CUI Id	C0009917
MeSH Codes	C05
Disease Class Name	Musculoskeletal Diseases
Semantic Type	Anatomical Abnormality
Human Phenotype Ontology Id	HP:0000924 HP:0003549 HP:0003011
Human Phenotype Ontology Term	Abnormality of the skeletal system; Abnormality of connective tissue; Abnormality of the musculature
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00469	BXGT003926	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2	5352	reviewed	Enzyme
O14656	BXGT004080	Torsin-1A	1861	reviewed	Chaperone
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02458	BXGT005879	Collagen alpha-1(II) chain	1280	reviewed
P02461	BXGT005880	Collagen alpha-1(III) chain	1281	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02760	BXGT005948	Protein AMBP	259	reviewed
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P11217	BXGT007674	Glycogen phosphorylase, muscle form	5837	reviewed	Enzyme
P12273	BXGT007787	Prolactin-inducible protein	5304	reviewed
P14555	BXGT008020	Phospholipase A2, membrane associated	5320	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P19634	BXGT008504	Sodium/hydrogen exchanger 1	6548	reviewed	Transporter
P20807	BXGT008601	Calpain-3	825	reviewed	Enzyme
P21817	BXGT008693	Ryanodine receptor 1	6261	reviewed	Ion channel
P28300	BXGT009243	Protein-lysine 6-oxidase	4015	reviewed
P31415	BXGT009537	Calsequestrin-1	844	reviewed
P51884	BXGT010903	Lumican	4060	reviewed
P58335	BXGT011233	Anthrax toxin receptor 2	118429	reviewed	Receptor
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P98066	BXGT012225	Tumor necrosis factor-inducible gene 6 protein	7130	reviewed
P98160	BXGT012228	Basement membrane-specific heparan sulfate proteoglycan core protein	3339	reviewed	Enzyme modulator
Q05397	BXGT012815	Focal adhesion kinase 1	5747	reviewed	Kinase
Q13698	BXGT013392	Voltage-dependent L-type calcium channel subunit alpha-1S	779	reviewed	Ion channel
Q16637	BXGT013646	Survival motor neuron protein	6607	reviewed	Epigenetic regulator
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q6ZQY3	BXGT016636	Acidic amino acid decarboxylase GADL1	339896	reviewed
Q8TDS5	BXGT018813	Oxoeicosanoid receptor 1	165140	reviewed	G-protein coupled receptor
Q8TDV0	BXGT018815	Probable G-protein coupled receptor 151	134391	reviewed	G-protein coupled receptor
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q96A70	BXGT019615	Antizyme inhibitor 2	113451	reviewed	Enzyme
Q96PU5	BXGT019711	E3 ubiquitin-protein ligase NEDD4-like	23327	reviewed	Enzyme
Q9H3H5	BXGT020461	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	1798	reviewed	Enzyme
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9ULV1	BXGT021764	Frizzled-4	8322	reviewed	G-protein coupled receptor
Q9Y3Z3	BXGT022268	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	25939	reviewed
Q15878	BXGT022659	Voltage-dependent R-type calcium channel subunit alpha-1E	777	reviewed	Ion channel

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}