Showing entry for Protein AMBP


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005948
Protein NameProtein AMBP
Uniport IdP02760
GeneAMBP
Gene Id259
DomainKunitz_BPTI; Lipocalin
Pfam PF00014   PF00061  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007155 cell adhesion
Biological Process GO:0007565 female pregnancy
Biological Process GO:0042167 heme catabolic process
Biological Process GO:0050777 negative regulation of immune response
Biological Process GO:0046329 negative regulation of JNK cascade
Biological Process GO:0030163 protein catabolic process
Biological Process GO:0018298 protein-chromophore linkage
Biological Process GO:0006898 receptor-mediated endocytosis
Biological Process GO:0016032 viral process
molecular function GO:0019855 calcium channel inhibitor activity
molecular function GO:0046904 calcium oxalate binding
molecular function GO:0020037 heme binding
molecular function GO:0019862 IgA binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0004867 serine-type endopeptidase inhibitor activity
cellular component GO:0072562 blood microparticle
cellular component GO:0009986 cell surface
cellular component GO:0062023 collagen-containing extracellular matrix
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-2168880 Scavenging of heme from plasma
R-HSA-2173782 Binding and Uptake of Ligands by Scavenger Receptors
R-HSA-5653656 Vesicle-mediated transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002986 BXGD000165 Fabry Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Cardiovascular Diseases
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004610 BXGD000281 Bacteremia Pathological Conditions, Signs and Symptoms; Infections
C0004623 BXGD000282 Bacterial Infections Infections
C0004626 BXGD000283 Pneumonia, Bacterial Infections; Respiratory Tract Diseases
C0004659 BXGD000284 Bacteriuria Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0005683 BXGD000318 Urinary Bladder Calculi (disorder) Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005686 BXGD000320 Urinary Bladder Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005697 BXGD000324 Neurogenic Urinary Bladder Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Nervous System Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007138 BXGD000446 Carcinoma, Transitional Cell Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0008479 BXGD000544 Chondrosarcoma Neoplasms
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009806 BXGD000633 Constipation Pathological Conditions, Signs and Symptoms
C0009917 BXGD000635 Contracture Musculoskeletal Diseases
C0010692 BXGD000686 Cystitis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0011206 BXGD000703 Delirium Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013221 BXGD000804 Drug toxicity Chemically-Induced Disorders
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014118 BXGD000894 Endocarditis Cardiovascular Diseases
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0015732 BXGD001018 Fecal Incontinence Digestive System Diseases
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0016199 BXGD001049 Flank Pain Pathological Conditions, Signs and Symptoms
C0017638 BXGD001132 Glioma Neoplasms
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018965 BXGD001258 Hematuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0019069 BXGD001277 Hemophilia A Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019193 BXGD001299 Hepatitis, Toxic Digestive System Diseases; Chemically-Induced Disorders
C0020295 BXGD001372 Hydronephrosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021831 BXGD001516 Intestinal Diseases Digestive System Diseases
C0022650 BXGD001568 Kidney Calculi Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024530 BXGD001783 Malaria Infections
C0025229 BXGD001839 Melioidosis Infections
C0025289 BXGD001851 Meningitis Nervous System Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027626 BXGD002005 Neoplasm Invasiveness Pathological Conditions, Signs and Symptoms; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0028734 BXGD002080 Nocturia Pathological Conditions, Signs and Symptoms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032463 BXGD002357 Polycythemia Vera Neoplasms; Hemic and Lymphatic Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0033581 BXGD002410 prostatitis Male Urogenital Diseases
C0034186 BXGD002469 Pyelonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0035078 BXGD002505 Kidney Failure Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0035243 BXGD002522 Respiratory Tract Infections Infections; Respiratory Tract Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0041755 BXGD002933 Adverse reaction to drug Chemically-Induced Disorders
C0041960 BXGD002943 Ureterocele Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042029 BXGD002951 Urinary tract infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0042580 BXGD002992 Vesico-Ureteral Reflux Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042998 BXGD003021 Vulvovaginitis Female Urogenital Diseases and Pregnancy Complications
C0085136 BXGD003131 Central Nervous System Neoplasms Neoplasms; Nervous System Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085293 BXGD003154 Hepatitis E Digestive System Diseases; Infections
C0149801 BXGD003367 Sepsis due to urinary tract infection Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0149871 BXGD003375 Deep Vein Thrombosis Cardiovascular Diseases
C0152020 BXGD003519 Gastroparesis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0162531 BXGD003950 Hereditary Coproporphyria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0238506 BXGD004941 Congenital posterior urethral valves Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0242350 BXGD005154 Erectile dysfunction Male Urogenital Diseases; Mental Disorders
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0262380 BXGD005232 Asymptomatic bacteriuria Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0262421 BXGD005239 Chronic urinary tract infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0262655 BXGD005264 Recurrent urinary tract infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0264714 BXGD005416 Acute heart failure Cardiovascular Diseases
C0265706 BXGD005570 Gastroschisis Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0275524 BXGD006376 Coinfection Infections
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0346990 BXGD007842 Carcinomatosis of peritoneal cavity Digestive System Diseases; Neoplasms
C0392525 BXGD008052 Nephrolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0404484 BXGD008319 Chronic pelvic pain of female Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0520575 BXGD009096 Acute pyelonephritis Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0543800 BXGD009294 Idiopathic hypercalciuria Pathological Conditions, Signs and Symptoms
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600041 BXGD009685 Infective cystitis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684275 BXGD009792 Hemophilia, NOS Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0694549 BXGD009851 Community acquired pneumonia Infections; Respiratory Tract Diseases
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0743841 BXGD010085 Disorder characterized by fever Pathological Conditions, Signs and Symptoms
C0744058 BXGD010087 flexor tenosynovitis
C0852036 BXGD010934 Pregnancy associated hypertension Female Urogenital Diseases and Pregnancy Complications; Cardiovascular Diseases
C0860207 BXGD011220 Drug-Induced Liver Disease Digestive System Diseases; Chemically-Induced Disorders
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0949083 BXGD011569 Hospital acquired pneumonia Pathological Conditions, Signs and Symptoms; Infections; Respiratory Tract Diseases
C1112209 BXGD011652 Abdominal Infection Infections
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1262760 BXGD011886 Hepatitis, Drug-Induced Digestive System Diseases; Chemically-Induced Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1443237 BXGD013069 Healthcare associated pneumonia Pathological Conditions, Signs and Symptoms; Infections; Respiratory Tract Diseases
C1510475 BXGD013171 Diverticulosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1565662 BXGD013402 Acute Kidney Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1705254 BXGD013568 Neonatal Deformity Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1719672 BXGD013659 Severe Sepsis Pathological Conditions, Signs and Symptoms; Infections
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1833683 BXGD013938 NEPHROLITHIASIS, CALCIUM OXALATE Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2004461 BXGD016872 Bowel dysfunction Digestive System Diseases
C2242472 BXGD016973 Infection of bone Pathological Conditions, Signs and Symptoms; Infections; Musculoskeletal Diseases
C2316810 BXGD017030 Chronic kidney disease stage 5 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2609414 BXGD017182 Acute kidney injury Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2985280 BXGD018223 Blood Protein Measurement
C3658290 BXGD019256 Drug-Induced Acute Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C3711531 BXGD019395 Hdl Deficiency, Type 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C4087504 BXGD022156 Peritoneal dissemination
C4277682 BXGD022376 Chemical and Drug Induced Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4279912 BXGD022378 Chemically-Induced Liver Toxicity Digestive System Diseases; Chemically-Induced Disorders
C4285937 BXGD022464 Invasive bacterial infection
C4551858 BXGD023425 Vesicoureteral Reflux 1 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4552481 BXGD023505 Acute bacterial skin and skin structure infection
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein