Showing entry for Frizzled-4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021764
Protein NameFrizzled-4
Uniport IdQ9ULV1
GeneFZD4
Gene Id8322
DomainFrizzled; Fz
Pfam PF01534   PF01392  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04150 mTOR signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04310 Wnt signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04390 Hippo signaling pathway
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells
5. Organismal Systems 5.2 Endocrine system hsa04916 Melanogenesis
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04934 Cushing syndrome
6. Human Diseases 6.9 Infectious diseases: Viral hsa05165 Human papillomavirus infection
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
6. Human Diseases 6.1 Cancers: Overview hsa05205 Proteoglycans in cancer
6. Human Diseases 6.2 Cancers: Specific types hsa05217 Basal cell carcinoma
6. Human Diseases 6.2 Cancers: Specific types hsa05224 Breast cancer
6. Human Diseases 6.2 Cancers: Specific types hsa05225 Hepatocellular carcinoma
6. Human Diseases 6.2 Cancers: Specific types hsa05226 Gastric cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0060070 canonical Wnt signaling pathway
Biological Process GO:1990830 cellular response to leukemia inhibitory factor
Biological Process GO:0071300 cellular response to retinoic acid
Biological Process GO:0061301 cerebellum vasculature morphogenesis
Biological Process GO:0035426 extracellular matrix-cell signaling
Biological Process GO:0031987 locomotion involved in locomotory behavior
Biological Process GO:0061024 membrane organization
Biological Process GO:0090090 negative regulation of canonical Wnt signaling pathway
Biological Process GO:0010812 negative regulation of cell-substrate adhesion
Biological Process GO:0030182 neuron differentiation
Biological Process GO:0035567 non-canonical Wnt signaling pathway
Biological Process GO:0110135 Norrin signaling pathway
Biological Process GO:0051091 positive regulation of DNA-binding transcription factor activity
Biological Process GO:0043507 positive regulation of JUN kinase activity
Biological Process GO:0150012 positive regulation of neuron projection arborization
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0042701 progesterone secretion
Biological Process GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway
Biological Process GO:0061304 retinal blood vessel morphogenesis
Biological Process GO:0061299 retina vasculature morphogenesis in camera-type eye
Biological Process GO:0007605 sensory perception of sound
Biological Process GO:0034446 substrate adhesion-dependent cell spreading
Biological Process GO:0001570 vasculogenesis
Biological Process GO:0016055 Wnt signaling pathway
Biological Process GO:0007223 Wnt signaling pathway, calcium modulating pathway
Biological Process GO:0060071 Wnt signaling pathway, planar cell polarity pathway
molecular function GO:0001540 amyloid-beta binding
molecular function GO:0019955 cytokine binding
molecular function GO:0004896 cytokine receptor activity
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0030165 PDZ domain binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0038023 signaling receptor activity
molecular function GO:0031625 ubiquitin protein ligase binding
molecular function GO:0042813 Wnt-activated receptor activity
molecular function GO:0017147 Wnt-protein binding
cellular component GO:0005911 cell-cell junction
cellular component GO:0009986 cell surface
cellular component GO:0030669 clathrin-coated endocytic vesicle membrane
cellular component GO:0030665 clathrin-coated vesicle membrane
cellular component GO:0030425 dendrite
cellular component GO:0005615 extracellular space
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-195721 Signaling by WNT
R-HSA-195721 Signaling by WNT
R-HSA-199991 Membrane Trafficking
R-HSA-201681 TCF dependent signaling in response to WNT
R-HSA-372790 Signaling by GPCR
R-HSA-373080 Class B/2 (Secretin family receptors)
R-HSA-3858494 Beta-catenin independent WNT signaling
R-HSA-3858494 Beta-catenin independent WNT signaling
R-HSA-4086398 Ca2+ pathway
R-HSA-4086398 Ca2+ pathway
R-HSA-4086400 PCP/CE pathway
R-HSA-4608870 Asymmetric localization of PCP proteins
R-HSA-4641263 Regulation of FZD by ubiquitination
R-HSA-4791275 Signaling by WNT in cancer
R-HSA-500792 GPCR ligand binding
R-HSA-5099900 WNT5A-dependent internalization of FZD4
R-HSA-5340588 RNF mutants show enhanced WNT signaling and proliferation
R-HSA-5653656 Vesicle-mediated transport
R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers
R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis
R-HSA-8856828 Clathrin-mediated endocytosis
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001807 BXGD000077 Aggressive behavior Behavior and Behavior Mechanisms
C0001916 BXGD000089 Albinism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003504 BXGD000202 Aortic Valve Insufficiency Cardiovascular Diseases
C0003706 BXGD000215 Arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004608 BXGD000280 Retinopathy background Eye Diseases
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005754 BXGD000334 Congenital blindness Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Eye Diseases; Nervous System Diseases
C0005779 BXGD000336 Blood Coagulation Disorders Hemic and Lymphatic Diseases
C0005818 BXGD000338 Blood Platelet Disorders Hemic and Lymphatic Diseases
C0006111 BXGD000369 Brain Diseases Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0007129 BXGD000439 Merkel cell carcinoma Neoplasms; Infections
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007682 BXGD000471 CNS disorder Nervous System Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008925 BXGD000575 Cleft Palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009777 BXGD000630 Conn Adenoma Neoplasms; Endocrine System Diseases
C0009917 BXGD000635 Contracture Musculoskeletal Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011119 BXGD000698 Decompression Sickness Wounds and Injuries
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0015397 BXGD000983 Disorder of eye Eye Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017601 BXGD001125 Glaucoma Eye Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0017921 BXGD001152 Glycogen storage disease type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0018213 BXGD001187 Graves Disease Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018834 BXGD001238 Heartburn Pathological Conditions, Signs and Symptoms
C0020175 BXGD001362 Hunger Behavior and Behavior Mechanisms
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020473 BXGD001396 Hyperlipidemia Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021053 BXGD001476 Immune System Diseases Immune System Diseases
C0021122 BXGD001481 Disruptive, Impulse Control, and Conduct Disorders Mental Disorders
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0022680 BXGD001576 Polycystic Kidney Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0024106 BXGD001730 Lumpy Skin Disease Infections; Animal Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024530 BXGD001783 Malaria Infections
C0025202 BXGD001832 melanoma Neoplasms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027533 BXGD001995 Neck Neoplasms Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027873 BXGD002054 Neuromyelitis Optica Eye Diseases; Immune System Diseases; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030521 BXGD002235 Parathyroid Neoplasms Neoplasms; Endocrine System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0035204 BXGD002511 Respiration Disorders Respiratory Tract Diseases
C0035242 BXGD002521 Respiratory Tract Diseases Respiratory Tract Diseases
C0035305 BXGD002529 Retinal Detachment Eye Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0035313 BXGD002532 Retinal Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0035320 BXGD002535 Retinal Neovascularization Pathological Conditions, Signs and Symptoms; Eye Diseases
C0035344 BXGD002541 Retinopathy of Prematurity Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0035435 BXGD002549 Rheumatism Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0036220 BXGD002587 Kaposi Sarcoma Neoplasms; Infections
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0039075 BXGD002788 Syndactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0042909 BXGD003013 Vitreous Hemorrhage Pathological Conditions, Signs and Symptoms; Eye Diseases
C0085580 BXGD003191 Essential Hypertension Cardiovascular Diseases
C0085762 BXGD003251 Alcohol abuse Chemically-Induced Disorders; Mental Disorders
C0086543 BXGD003294 Cataract Eye Diseases
C0087169 BXGD003321 Withdrawal Symptoms Chemically-Induced Disorders; Mental Disorders
C0150055 BXGD003401 Chronic pain Pathological Conditions, Signs and Symptoms
C0151526 BXGD003432 Premature Birth Female Urogenital Diseases and Pregnancy Complications
C0154828 BXGD003745 Traction detachment of retina Eye Diseases
C0154832 BXGD003747 Exudative retinopathy Eye Diseases; Cardiovascular Diseases
C0162283 BXGD003927 Nephrogenic Diabetes Insipidus Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0162770 BXGD003980 Right Ventricular Hypertrophy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0220633 BXGD004303 Uveal melanoma Neoplasms; Eye Diseases
C0220659 BXGD004314 Acrodysostosis Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0221002 BXGD004360 Hyperparathyroidism, Primary Endocrine System Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0234632 BXGD004691 Reduced visual acuity Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0235259 BXGD004735 Subcapsular cataract Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0235991 BXGD004802 Small for gestational age (disorder) Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0240897 BXGD005060 Retinal exudates
C0242363 BXGD005156 Islet Cell Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0243050 BXGD005212 Cardiovascular Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0265553 BXGD005547 Polysyndactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0266526 BXGD005687 Norrie disease Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases
C0266559 BXGD005694 Persistent primary vitreous Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0266568 BXGD005695 Persistent Hyperplastic Primary Vitreous Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0271055 BXGD006154 Rhegmatogenous retinal detachment Eye Diseases
C0271084 BXGD006159 Exudative age-related macular degeneration Eye Diseases
C0271097 BXGD006163 Usher Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0282687 BXGD006826 Hemorrhagic Fever, Ebola Infections
C0302511 BXGD006849 Small for gestational age fetus Pathological Conditions, Signs and Symptoms
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0338908 BXGD007218 Mixed anxiety and depressive disorder Mental Disorders
C0339383 BXGD007245 Choroidal and/or chorioretinal disorder Eye Diseases
C0339539 BXGD007265 Familial Exudative Vitreoretinopathy
C0342384 BXGD007470 Idiopathic hypogonadotropic hypogonadism Endocrine System Diseases
C0342443 BXGD007481 Adrenal Cushing's syndrome Endocrine System Diseases
C0342649 BXGD007522 Vascular calcification Nutritional and Metabolic Diseases
C0342684 BXGD007525 Ocular albinism, type I Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C0344290 BXGD007662 Vitreoretinal degeneration
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0344550 BXGD007694 Congenital retinal fold
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376634 BXGD008006 Craniofacial Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0392514 BXGD008051 Hereditary hemochromatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0392784 BXGD008069 Dermatofibrosarcoma Protuberans Neoplasms
C0393642 BXGD008111 Sepsis-Associated Encephalopathy Nervous System Diseases
C0423361 BXGD008482 Posterior Vitreous Detachment Eye Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0456909 BXGD008883 Blindness Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0553665 BXGD009405 Skin endocrine disorder Skin and Connective Tissue Diseases
C0563625 BXGD009484 Agnosia for Pain Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0580174 BXGD009556 Portal hypertensive gastropathy Digestive System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598935 BXGD009674 Tumor Initiation Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0751569 BXGD010504 Genitourinary Cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0795841 BXGD010746 Jacobsen Distal 11q Deletion Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0854723 BXGD011026 Retinal Dystrophies Eye Diseases
C0856169 BXGD011096 Endothelial dysfunction
C0857116 BXGD011137 Gross obesity
C0858600 BXGD011182 Taste sweet
C0877008 BXGD011325 Enzyme inhibition disorder
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0948089 BXGD011504 Acute Coronary Syndrome Cardiovascular Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1264039 BXGD011909 von Willebrand Disease, Type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1285162 BXGD012167 Degenerative disorder Pathological Conditions, Signs and Symptoms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1334386 BXGD012702 Meningeal melanoma
C1337011 BXGD012874 Well Differentiated Pancreatic Endocrine Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1337013 BXGD012876 Differentiated Thyroid Gland Carcinoma
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1611743 BXGD013456 Familial (FPAH)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1837218 BXGD014207 Cleft palate, isolated Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C1839839 BXGD014416 MAJOR AFFECTIVE DISORDER 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Mental Disorders
C1840311 BXGD014445 Laryngeal cleft Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1840348 BXGD014451 Hypocalciuric Hypercalcemia, Acquired Nutritional and Metabolic Diseases
C1843517 BXGD014593 Retinal arteriolar tortuosity
C1847352 BXGD014859 POLYMICROGYRIA, BILATERAL FRONTOPARIETAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1851402 BXGD015211 Exudative vitreoretinopathy 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1851406 BXGD015212 Peripheral retinal avascularization
C1852197 BXGD015264 MAJOR AFFECTIVE DISORDER 1 Mental Disorders
C1852767 BXGD015296 Hereditary macular coloboma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1854494 BXGD015409 Slow progression
C1857299 BXGD015693 RETINAL NONATTACHMENT, NONSYNDROMIC CONGENITAL Eye Diseases
C1857451 BXGD015702 Acth-Independent Macronodular Adrenal Hyperplasia Endocrine System Diseases
C1858262 BXGD015779 EXUDATIVE VITREORETINOPATHY, DIGENIC
C1970943 BXGD016852 MAJOR AFFECTIVE DISORDER 4 Mental Disorders
C1970945 BXGD016853 MAJOR AFFECTIVE DISORDER 6 Mental Disorders
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3489532 BXGD018934 Cone-Rod Dystrophy 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3693482 BXGD019337 Giant Cell Fibroblastoma Neoplasms
C3805574 BXGD019481 Increased fracture rate
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4072980 BXGD022028 Exudative vitreoretinopathy
C4520679 BXGD023033 Abnormal macular morphology Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C4529962 BXGD023178 Fatty Liver Disease
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722172 BXGD023791 Primary differentiated carcinoma of thyroid gland
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002825 Hexadecenoic acid 254.41
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein