Showing entry for Congenital Hypothyroidism


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000661
Disease NameCongenital Hypothyroidism
Disease CUI IdC0010308
MeSH Codes C16   C05   C19  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000818  
Human Phenotype Ontology TermAbnormality of the endocrine system
Disease Ontology Id DOID:630   DOID:7  
Disease Ontology Class Namegenetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O15550 BXGT004179 Lysine-specific demethylase 6A 7403 reviewed Epigenetic regulator
O75340 BXGT005112 Programmed cell death protein 6 10016 reviewed
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02818 BXGT005969 Osteocalcin 632 reviewed
P05543 BXGT006366 Thyroxine-binding globulin 6906 reviewed Enzyme modulator
P07202 BXGT006565 Thyroid peroxidase 7173 reviewed Enzyme
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P08138 BXGT006729 Tumor necrosis factor receptor superfamily member 16 4804 reviewed Receptor
P09104 BXGT006856 Gamma-enolase 2026 reviewed Enzyme
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P10827 BXGT007623 Thyroid hormone receptor alpha 7067 reviewed Nuclear receptor
P10828 BXGT007624 Thyroid hormone receptor beta 7068 reviewed Nuclear receptor
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P16473 BXGT008234 Thyrotropin receptor 7253 reviewed G-protein coupled receptor
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P34972 BXGT009779 Cannabinoid receptor 2 1269 reviewed G-protein coupled receptor
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P52803 BXGT010958 Ephrin-A5 1946 reviewed Signaling
P52952 BXGT010966 Homeobox protein Nkx-2.5 1482 reviewed Transcription factor
P54756 BXGT011074 Ephrin type-A receptor 5 2044 reviewed Kinase
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
P78504 BXGT011844 Protein jagged-1 182 reviewed
Q01718 BXGT012609 Adrenocorticotropic hormone receptor 4158 reviewed G-protein coupled receptor
Q06710 BXGT012887 Paired box protein Pax-8 7849 reviewed
Q08499 BXGT012988 cAMP-specific 3',5'-cyclic phosphodiesterase 4D 5144 reviewed
Q13423 BXGT013352 NAD(P) transhydrogenase, mitochondrial 23530 reviewed Enzyme
Q13510 BXGT013367 Acid ceramidase 427 reviewed Enzyme
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q9H4B7 BXGT020475 Tubulin beta-1 chain 81027 reviewed Cellular structure
Q9NNW7 BXGT021139 Thioredoxin reductase 2, mitochondrial 10587 reviewed Enzyme
Q9NRX4 BXGT021198 14 kDa phosphohistidine phosphatase 29085 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q92911 BXGT022650 Sodium/iodide cotransporter 6528 reviewed Transporter
Q8IVT5 BXGT026146 Kinase suppressor of Ras 1 8844 reviewed Kinase
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease