Showing entry for Experimental Autoimmune Encephalomyelitis


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000888
Disease NameExperimental Autoimmune Encephalomyelitis
Disease CUI IdC0014072
MeSH Codes C20   C10  
Disease Class NameImmune System Diseases; Nervous System Diseases
Semantic TypeExperimental Model of Disease
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
P01023 BXGT005718 Alpha-2-macroglobulin 2 reviewed Enzyme modulator
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01730 BXGT005781 T-cell surface glycoprotein CD4 920 reviewed
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01920 BXGT005817 HLA class II histocompatibility antigen, DQ beta 1 chain 3119 reviewed Immune response
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3156 reviewed
P04083 BXGT006147 Annexin A1 301 reviewed
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P05231 BXGT006345 Interleukin-6 3569 reviewed
P08138 BXGT006729 Tumor necrosis factor receptor superfamily member 16 4804 reviewed Receptor
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09619 BXGT006911 Platelet-derived growth factor receptor beta 5159 reviewed Kinase
P10147 BXGT007543 C-C motif chemokine 3 6348 reviewed Signaling
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P13612 BXGT007928 Integrin alpha-4 3676 reviewed
P13671 BXGT007941 Complement component C6 729 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P23219 BXGT008837 Prostaglandin G/H synthase 1 5742 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P29460 BXGT009348 Interleukin-12 subunit beta 3593 reviewed Signaling
P33681 BXGT009739 T-lymphocyte activation antigen CD80 941 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P52333 BXGT010928 Tyrosine-protein kinase JAK3 3718 reviewed Kinase
P53634 BXGT011007 Dipeptidyl peptidase 1 1075 reviewed Enzyme
P55087 BXGT011105 Aquaporin-4 361 reviewed Ion channel
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P61586 BXGT011375 Transforming protein RhoA 387 reviewed Enzyme modulator
P78536 BXGT011847 Disintegrin and metalloproteinase domain-containing protein 17 6868 reviewed
Q00975 BXGT012558 Voltage-dependent N-type calcium channel subunit alpha-1B 774 reviewed Ion channel
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q13191 BXGT013325 E3 ubiquitin-protein ligase CBL-B 868 reviewed Enzyme
Q13478 BXGT013362 Interleukin-18 receptor 1 8809 reviewed Receptor
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q5Y7D3 BXGT015912 HLA class II histocompatibility antigen DQ beta chain 3119 unreviewed
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96IY4 BXGT019678 Carboxypeptidase B2 1361 reviewed Enzyme
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P98082 BXGT025047 Disabled homolog 2 1601 reviewed Signaling
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease