protein

Showing entry for T-lymphocyte activation antigen CD80

General Target Information
BXGT Id	BXGT009739
Protein Name	T-lymphocyte activation antigen CD80
Uniport Id	P33681
Gene	CD80
Gene Id	941
Domain	C2-set_2; V-set
Pfam	PF08205 PF07686
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name
3. Environmental Information Processing	3.3 Signaling molecules and interaction	hsa04514	Cell adhesion molecules (CAMs)
5. Organismal Systems	5.1 Immune system	hsa04620	Toll-like receptor signaling pathway
5. Organismal Systems	5.1 Immune system	hsa04672	Intestinal immune network for IgA production
6. Human Diseases	6.7 Endocrine and metabolic diseases	hsa04940	Type I diabetes mellitus
6. Human Diseases	6.3 Immune diseases	hsa05320	Autoimmune thyroid disease
6. Human Diseases	6.3 Immune diseases	hsa05322	Systemic lupus erythematosus
6. Human Diseases	6.3 Immune diseases	hsa05323	Rheumatoid arthritis
6. Human Diseases	6.3 Immune diseases	hsa05330	Allograft rejection
6. Human Diseases	6.3 Immune diseases	hsa05332	Graft-versus-host disease
6. Human Diseases	6.6 Cardiovascular diseases	hsa05416	Viral myocarditis

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0007166	cell surface receptor signaling pathway
Biological Process	GO:0071222	cellular response to lipopolysaccharide
Biological Process	GO:0019221	cytokine-mediated signaling pathway
Biological Process	GO:0006955	immune response
Biological Process	GO:0035556	intracellular signal transduction
Biological Process	GO:0042130	negative regulation of T cell proliferation
Biological Process	GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
Biological Process	GO:0032743	positive regulation of interleukin-2 production
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
Biological Process	GO:0051897	positive regulation of protein kinase B signaling
Biological Process	GO:0009967	positive regulation of signal transduction
Biological Process	GO:0042102	positive regulation of T cell proliferation
Biological Process	GO:0045627	positive regulation of T-helper 1 cell differentiation
Biological Process	GO:0045893	positive regulation of transcription, DNA-templated
Biological Process	GO:0007165	signal transduction
Biological Process	GO:0031295	T cell costimulation
molecular function	GO:0015026	coreceptor activity
molecular function	GO:0001618	virus receptor activity
cellular component	GO:0009986	cell surface
cellular component	GO:0009897	external side of plasma membrane
cellular component	GO:0016021	integral component of membrane
cellular component	GO:0005886	plasma membrane
cellular component	GO:0098636	protein complex involved in cell adhesion

Reactome

Pathway Id	Pathway Name
R-HSA-1257604	PIP3 activates AKT signaling
R-HSA-1280215	Cytokine Signaling in Immune system
R-HSA-1280218	Adaptive Immune System
R-HSA-162582	Signal Transduction
R-HSA-1643685	Disease
R-HSA-168256	Immune System
R-HSA-199418	Negative regulation of the PI3K/AKT network
R-HSA-2219528	PI3K/AKT Signaling in Cancer
R-HSA-2219530	Constitutive Signaling by Aberrant PI3K in Cancer
R-HSA-388841	Costimulation by the CD28 family
R-HSA-389356	CD28 co-stimulation
R-HSA-389357	CD28 dependent PI3K/Akt signaling
R-HSA-389359	CD28 dependent Vav1 pathway
R-HSA-389513	CTLA4 inhibitory signaling
R-HSA-449147	Signaling by Interleukins
R-HSA-5663202	Diseases of signal transduction by growth factor receptors and second messengers
R-HSA-6783783	Interleukin-10 signaling
R-HSA-6811558	PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
R-HSA-9006925	Intracellular signaling by second messengers

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0001418	BXGD000050	Adenocarcinoma	Neoplasms
C0001430	BXGD000054	Adenoma	Neoplasms
C0002395	BXGD000111	Alzheimer's Disease	Nervous System Diseases; Mental Disorders
C0002792	BXGD000129	anaphylaxis	Immune System Diseases
C0002986	BXGD000165	Fabry Disease	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Cardiovascular Diseases
C0003850	BXGD000225	Arteriosclerosis	Cardiovascular Diseases
C0003864	BXGD000231	Arthritis	Musculoskeletal Diseases
C0003872	BXGD000235	Arthritis, Psoriatic	Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0003873	BXGD000236	Rheumatoid Arthritis	Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096	BXGD000252	Asthma	Respiratory Tract Diseases; Immune System Diseases
C0004153	BXGD000260	Atherosclerosis	Cardiovascular Diseases
C0004364	BXGD000270	Autoimmune Diseases	Immune System Diseases
C0004623	BXGD000282	Bacterial Infections	Infections
C0004763	BXGD000289	Barrett Esophagus	Digestive System Diseases; Neoplasms
C0005684	BXGD000319	Malignant neoplasm of urinary bladder	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695	BXGD000323	Bladder Neoplasm	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006118	BXGD000372	Brain Neoplasms	Neoplasms; Nervous System Diseases
C0006142	BXGD000374	Malignant neoplasm of breast	Neoplasms; Skin and Connective Tissue Diseases
C0006826	BXGD000408	Malignant Neoplasms	Neoplasms
C0007102	BXGD000425	Malignant tumor of colon	Digestive System Diseases; Neoplasms
C0007131	BXGD000441	Non-Small Cell Lung Carcinoma	Neoplasms; Respiratory Tract Diseases
C0007134	BXGD000443	Renal Cell Carcinoma	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137	BXGD000445	Squamous cell carcinoma	Neoplasms
C0007570	BXGD000467	Celiac Disease	Digestive System Diseases; Nutritional and Metabolic Diseases
C0007847	BXGD000492	Malignant tumor of cervix	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008312	BXGD000527	Primary biliary cirrhosis	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0009324	BXGD000597	Ulcerative Colitis	Digestive System Diseases
C0009376	BXGD000603	Colonic Polyps	Pathological Conditions, Signs and Symptoms
C0009402	BXGD000605	Colorectal Carcinoma	Digestive System Diseases; Neoplasms
C0010232	BXGD000655	Cowpox	Infections
C0010246	BXGD000656	Coxsackievirus Infections	Infections
C0010346	BXGD000664	Crohn Disease	Digestive System Diseases
C0011847	BXGD000749	Diabetes	Endocrine System Diseases
C0011849	BXGD000751	Diabetes Mellitus	Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854	BXGD000753	Diabetes Mellitus, Insulin-Dependent	Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011881	BXGD000760	Diabetic Nephropathy	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0013595	BXGD000858	Eczema	Skin and Connective Tissue Diseases
C0014070	BXGD000887	Encephalomyelitis	Infections; Nervous System Diseases
C0014072	BXGD000888	Experimental Autoimmune Encephalomyelitis	Immune System Diseases; Nervous System Diseases
C0014457	BXGD000915	Eosinophilia	Hemic and Lymphatic Diseases
C0014859	BXGD000961	Esophageal Neoplasms	Digestive System Diseases; Neoplasms
C0015397	BXGD000983	Disorder of eye	Eye Diseases
C0015403	BXGD000985	Eye Infection	Infections; Eye Diseases
C0017638	BXGD001132	Glioma	Neoplasms
C0017661	BXGD001139	IGA Glomerulonephritis	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0017668	BXGD001143	Focal glomerulosclerosis	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0018133	BXGD001176	Graft-vs-Host Disease	Immune System Diseases
C0018213	BXGD001187	Graves Disease	Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0018378	BXGD001190	Guillain-Barre Syndrome	Immune System Diseases; Nervous System Diseases
C0018818	BXGD001236	Ventricular Septal Defects	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0019158	BXGD001293	Hepatitis	Digestive System Diseases
C0019163	BXGD001295	Hepatitis B	Digestive System Diseases; Infections
C0019196	BXGD001301	Hepatitis C	Digestive System Diseases; Infections
C0019348	BXGD001325	Herpes Simplex Infections	Infections; Skin and Connective Tissue Diseases
C0019693	BXGD001346	HIV Infections	Infections; Immune System Diseases
C0019829	BXGD001350	Hodgkin Disease	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020676	BXGD001462	Hypothyroidism	Endocrine System Diseases
C0021390	BXGD001503	Inflammatory Bowel Diseases	Digestive System Diseases
C0021400	BXGD001504	Influenza	Infections; Respiratory Tract Diseases
C0022104	BXGD001529	Irritable Bowel Syndrome	Digestive System Diseases
C0022658	BXGD001570	Kidney Diseases	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660	BXGD001571	Kidney Failure, Acute	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022661	BXGD001572	Kidney Failure, Chronic	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023348	BXGD001636	Leprosy, Lepromatous	Infections
C0023418	BXGD001642	leukemia	Neoplasms
C0023434	BXGD001643	Chronic Lymphocytic Leukemia	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023449	BXGD001650	Acute lymphocytic leukemia	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452	BXGD001651	Childhood Acute Lymphoblastic Leukemia	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023465	BXGD001656	Acute monocytic leukemia	Neoplasms
C0023467	BXGD001658	Leukemia, Myelocytic, Acute	Neoplasms
C0023493	BXGD001672	Adult T-Cell Lymphoma/Leukemia	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023892	BXGD001715	Biliary cirrhosis	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024117	BXGD001734	Chronic Obstructive Airway Disease	Respiratory Tract Diseases
C0024131	BXGD001736	Lupus Vulgaris	Infections; Skin and Connective Tissue Diseases
C0024138	BXGD001738	Lupus Erythematosus, Discoid	Skin and Connective Tissue Diseases
C0024141	BXGD001740	Lupus Erythematosus, Systemic	Skin and Connective Tissue Diseases; Immune System Diseases
C0024143	BXGD001741	Lupus Nephritis	Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases
C0024266	BXGD001754	Lymphocytic Choriomeningitis	Infections; Nervous System Diseases
C0024299	BXGD001758	Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623	BXGD001791	Malignant neoplasm of stomach	Digestive System Diseases; Neoplasms
C0025202	BXGD001832	melanoma	Neoplasms
C0026764	BXGD001928	Multiple Myeloma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769	BXGD001930	Multiple Sclerosis	Immune System Diseases; Nervous System Diseases
C0027533	BXGD001995	Neck Neoplasms	Neoplasms
C0027627	BXGD002006	Neoplasm Metastasis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651	BXGD002009	Neoplasms	Neoplasms
C0027708	BXGD002025	Nephroblastoma	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027721	BXGD002029	Lipoid nephrosis	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027726	BXGD002030	Nephrotic Syndrome	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027819	BXGD002043	Neuroblastoma	Neoplasms
C0029456	BXGD002157	Osteoporosis	Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029925	BXGD002181	Ovarian Carcinoma	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0031090	BXGD002280	Periodontal Diseases	Stomatognathic Diseases
C0032285	BXGD002344	Pneumonia	Infections; Respiratory Tract Diseases
C0034887	BXGD002491	Rectal polyp	Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Neoplasms
C0035078	BXGD002505	Kidney Failure	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0035220	BXGD002512	Respiratory Distress Syndrome, Newborn	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0035235	BXGD002519	Respiratory Syncytial Virus Infections	Infections
C0036202	BXGD002581	Sarcoidosis	Hemic and Lymphatic Diseases
C0036220	BXGD002587	Kaposi Sarcoma	Neoplasms; Infections
C0036685	BXGD002629	Septicaemia due to gram-negative organism, unspecified	Pathological Conditions, Signs and Symptoms; Infections
C0036690	BXGD002632	Septicemia	Pathological Conditions, Signs and Symptoms; Infections
C0037221	BXGD002673	Situs Inversus	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0038356	BXGD002747	Stomach Neoplasms	Digestive System Diseases; Neoplasms
C0040147	BXGD002847	Thyroiditis	Endocrine System Diseases
C0041234	BXGD002901	Chagas Disease	Infections
C0041296	BXGD002903	Tuberculosis	Infections
C0042769	BXGD002999	Virus Diseases	Infections
C0042900	BXGD003012	Vitiligo	Skin and Connective Tissue Diseases
C0079731	BXGD003087	B-Cell Lymphomas	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079773	BXGD003100	Lymphoma, T-Cell, Cutaneous	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085655	BXGD003226	Polymyositis	Musculoskeletal Diseases; Nervous System Diseases
C0152013	BXGD003516	Adenocarcinoma of lung (disorder)	Neoplasms
C0152018	BXGD003518	Esophageal carcinoma	Digestive System Diseases; Neoplasms
C0152113	BXGD003543	Rheumatic Chorea	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0153381	BXGD003626	Malignant neoplasm of mouth	Neoplasms; Stomatognathic Diseases
C0155686	BXGD003811	Acute myocarditis	Cardiovascular Diseases
C0162820	BXGD003985	Dermatitis, Allergic Contact	Skin and Connective Tissue Diseases; Immune System Diseases
C0162823	BXGD003986	Dermatitis, Irritant	Skin and Connective Tissue Diseases
C0178468	BXGD004029	Autoimmune thyroid disease	Immune System Diseases; Endocrine System Diseases
C0206623	BXGD004189	Adenosquamous carcinoma	Neoplasms
C0206704	BXGD004254	Carcinoma, Large Cell	Neoplasms
C0206708	BXGD004256	Cervical Intraepithelial Neoplasia	Neoplasms
C0220630	BXGD004302	Adult Liver Carcinoma	Digestive System Diseases; Neoplasms
C0220633	BXGD004303	Uveal melanoma	Neoplasms; Eye Diseases
C0220641	BXGD004305	Lip and Oral Cavity Carcinoma	Neoplasms; Stomatognathic Diseases
C0220656	BXGD004312	Malignant ascites	Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Neoplasms
C0221026	BXGD004371	X-linked agammaglobulinemia	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C0232865	BXGD004566	Functional proteinuria	Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0235974	BXGD004796	Pancreatic carcinoma	Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238065	BXGD004869	Secondary Biliary Cholangitis	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0238790	BXGD004956	bone destruction
C0242379	BXGD005157	Malignant neoplasm of lung	Neoplasms; Respiratory Tract Diseases
C0243026	BXGD005210	Sepsis	Pathological Conditions, Signs and Symptoms; Infections
C0263680	BXGD005344	Chronic arthritis	Musculoskeletal Diseases
C0265325	BXGD005516	Turcot syndrome (disorder)	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Nervous System Diseases
C0268238	BXGD005862	Triglyceride storage disease with ichthyosis	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0270921	BXGD006133	Axonal neuropathy	Nervous System Diseases
C0272394	BXGD006363	Disorder of lymph node	Hemic and Lymphatic Diseases
C0275551	BXGD006379	Primary bacterial peritonitis	Digestive System Diseases; Infections
C0276138	BXGD006403	Viral myocarditis	Infections; Cardiovascular Diseases
C0278488	BXGD006515	Carcinoma breast stage IV
C0278678	BXGD006556	Metastatic Renal Cell Cancer
C0278701	BXGD006566	Gastric Adenocarcinoma	Digestive System Diseases; Neoplasms
C0279000	BXGD006622	Liver and Intrahepatic Biliary Tract Carcinoma	Digestive System Diseases; Neoplasms
C0279584	BXGD006641	Childhood B Acute Lymphoblastic Leukemia	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0279593	BXGD006644	Adult B Acute Lymphoblastic Leukemia
C0279702	BXGD006685	Conventional (Clear Cell) Renal Cell Carcinoma	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0302358	BXGD006842	Disease caused by Shigella dysenteriae	Digestive System Diseases; Infections
C0302592	BXGD006851	Cervix carcinoma	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333983	BXGD006975	Hyperplastic Polyp	Pathological Conditions, Signs and Symptoms
C0339143	BXGD007226	Thyroid associated opthalmopathies	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0340288	BXGD007316	Stable angina	Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0343401	BXGD007623	MRSA - Methicillin resistant Staphylococcus aureus infection	Infections
C0345904	BXGD007745	Malignant neoplasm of liver	Digestive System Diseases; Neoplasms
C0346647	BXGD007832	Malignant neoplasm of pancreas	Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0346989	BXGD007841	Secondary malignant neoplasm of peritoneum
C0346990	BXGD007842	Carcinomatosis of peritoneal cavity	Digestive System Diseases; Neoplasms
C0349566	BXGD007928	Squamous cell carcinoma of tongue	Neoplasms; Stomatognathic Diseases
C0349632	BXGD007939	Splenic Marginal Zone B-Cell Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0349636	BXGD007941	Pre B-cell acute lymphoblastic leukemia
C0393819	BXGD008151	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	Immune System Diseases; Nervous System Diseases
C0398689	BXGD008216	Hyper-IgM Immunodeficiency Syndrome, Type 1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C0403398	BXGD008278	Steroid-dependent nephrotic syndrome	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0409974	BXGD008401	Lupus Erythematosus	Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0442874	BXGD008814	Neuropathy	Nervous System Diseases
C0456909	BXGD008883	Blindness	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0524909	BXGD009247	Hepatitis B, Chronic	Digestive System Diseases; Infections
C0546837	BXGD009343	Malignant neoplasm of esophagus	Digestive System Diseases; Neoplasms
C0555198	BXGD009432	Malignant Glioma	Neoplasms
C0558356	BXGD009453	Malignant melanoma of eye	Neoplasms; Eye Diseases
C0595936	BXGD009628	Aqueous Humor Disorders	Eye Diseases
C0596263	BXGD009639	Carcinogenesis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0677607	BXGD009721	Hashimoto Disease	Endocrine System Diseases
C0678222	BXGD009749	Breast Carcinoma	Neoplasms; Skin and Connective Tissue Diseases
C0684249	BXGD009790	Carcinoma of lung	Neoplasms; Respiratory Tract Diseases
C0686619	BXGD009835	Secondary malignant neoplasm of lymph node	Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790	BXGD009866	Colon Carcinoma	Digestive System Diseases; Neoplasms
C0699791	BXGD009867	Stomach Carcinoma	Digestive System Diseases; Neoplasms
C0699885	BXGD009869	Carcinoma of bladder	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095	BXGD009875	Central neuroblastoma	Neoplasms; Nervous System Diseases
C0740380	BXGD009983	Varicella zoster
C0742343	BXGD010061	Acute Chest Syndrome	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0747845	BXGD010184	early pregnancy
C0751356	BXGD010406	Idiopathic Inflammatory Myopathies	Musculoskeletal Diseases; Nervous System Diseases
C0751606	BXGD010523	Adult Acute Lymphocytic Leukemia
C0919267	BXGD011426	ovarian neoplasm	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0948089	BXGD011504	Acute Coronary Syndrome	Cardiovascular Diseases
C0948264	BXGD011522	Neuroborreliosis	Infections
C1140680	BXGD011718	Malignant neoplasm of ovary	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269955	BXGD012005	Tumor Cell Invasion
C1275122	BXGD012060	Familial multiple trichoepitheliomata	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases
C1292769	BXGD012230	Precursor B-cell lymphoblastic leukemia	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1306459	BXGD012361	Primary malignant neoplasm	Neoplasms
C1306460	BXGD012362	Primary malignant neoplasm of lung	Neoplasms; Respiratory Tract Diseases
C1306759	BXGD012374	Eosinophilic disorder	Hemic and Lymphatic Diseases
C1318500	BXGD012395	Non-toxic nodular goiter	Endocrine System Diseases
C1332206	BXGD012504	Adult Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332309	BXGD012521	Anti-Basement Membrane Glomerulonephritis	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1332977	BXGD012569	Childhood Leukemia	Neoplasms
C1332979	BXGD012571	Childhood Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1519680	BXGD013244	Tumor Immunity	Pathological Conditions, Signs and Symptoms
C1533172	BXGD013311	Infantile nystagmus syndrome	Eye Diseases; Nervous System Diseases
C1561643	BXGD013363	Chronic Kidney Diseases	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1636149	BXGD013482	Macular dystrophy, corneal type 1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1704321	BXGD013544	Nephrotic Syndrome, Minimal Change	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1709661	BXGD013630	Primary Focal Segmental Glomerulosclerosis	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1832661	BXGD013866	ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1840264	BXGD014439	IMMUNE SUPPRESSION
C1851585	BXGD015222	MYELOPROLIFERATIVE DISORDER, CHRONIC, WITH EOSINOPHILIA	Hemic and Lymphatic Diseases
C1861305	BXGD016027	TARSAL-CARPAL COALITION SYNDROME	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1868683	BXGD016526	B-CELL MALIGNANCY, LOW-GRADE
C1956346	BXGD016627	Coronary Artery Disease	Cardiovascular Diseases
C1961102	BXGD016673	Precursor Cell Lymphoblastic Leukemia Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2239176	BXGD016965	Liver carcinoma	Digestive System Diseases; Neoplasms
C2316810	BXGD017030	Chronic kidney disease stage 5	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2607914	BXGD017148	Allergic rhinitis (disorder)	Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C2931822	BXGD018068	Nasopharyngeal carcinoma	Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2939419	BXGD018178	Secondary Neoplasm	Pathological Conditions, Signs and Symptoms; Neoplasms
C3266262	BXGD018600	Multiple Chronic Conditions	Pathological Conditions, Signs and Symptoms
C3496337	BXGD019020	Idiopathic Nephrotic Syndrome	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3714514	BXGD019409	Infection	Infections
C3825926	BXGD019707	Nephrotic syndrome in children
C4048328	BXGD021903	cervical cancer	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4048329	BXGD021904	Immunosuppression
C4086165	BXGD022126	Childhood Neuroblastoma	Neoplasms
C4520898	BXGD023047	Stage IV Breast Cancer AJCC v6 and v7
C4528561	BXGD023167	Anatomic Stage IV Breast Cancer AJCC v8
C4528592	BXGD023175	Prognostic Stage IV Breast Cancer AJCC v8
C4551595	BXGD023367	Biliary Cirrhosis, Primary, 1	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C4552766	BXGD023523	Miscarriage	Female Urogenital Diseases and Pregnancy Complications
C4721610	BXGD023760	Carcinoma, Ovarian Epithelial	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721698	BXGD023763	Metastatic Renal Cell Carcinoma	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0050194	alpha-D-Mannose		180.06

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}