Showing entry for Fatty Liver, Alcoholic


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001014
Disease NameFatty Liver, Alcoholic
Disease CUI IdC0015696
MeSH Codes C06   C25  
Disease Class NameDigestive System Diseases; Chemically-Induced Disorders
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:0014667   DOID:630  
Disease Ontology Class Namedisease of metabolism; genetic disease
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00763 BXGT003947 Acetyl-CoA carboxylase 2 32 reviewed
O00767 BXGT003949 Acyl-CoA desaturase 6319 reviewed
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 8714 reviewed Transporter
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O75581 BXGT005136 Low-density lipoprotein receptor-related protein 6 4040 reviewed
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00480 BXGT005551 Ornithine carbamoyltransferase, mitochondrial 5009 reviewed
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05177 BXGT006336 Cytochrome P450 1A2 1544 reviewed Enzyme
P05181 BXGT006337 Cytochrome P450 2E1 1571 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P10599 BXGT007583 Thioredoxin 7295 reviewed
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P18850 BXGT008433 Cyclic AMP-dependent transcription factor ATF-6 alpha 22926 reviewed
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P29508 BXGT009358 Serpin B3 6317 reviewed Enzyme modulator
P31327 BXGT009523 Carbamoyl-phosphate synthase [ammonia], mitochondrial 1373 reviewed Enzyme
P32245 BXGT009614 Melanocortin receptor 4 4160 reviewed G-protein coupled receptor
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35557 BXGT009846 Glucokinase 2645 reviewed Kinase
P36955 BXGT009946 Pigment epithelium-derived factor 5176 reviewed Enzyme modulator
P36956 BXGT009947 Sterol regulatory element-binding protein 1 6720 reviewed
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P43490 BXGT010395 Nicotinamide phosphoribosyltransferase 10135 reviewed Signaling
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P51687 BXGT010882 Sulfite oxidase, mitochondrial 6821 reviewed
P55157 BXGT011108 Microsomal triglyceride transfer protein large subunit 4547 reviewed Transporter
P55263 BXGT011115 Adenosine kinase 132 reviewed Kinase
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P62508 BXGT011431 Estrogen-related receptor gamma 2104 reviewed Nuclear receptor
P81172 BXGT011935 Hepcidin 57817 reviewed
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q13085 BXGT013309 Acetyl-CoA carboxylase 1 31 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14627 BXGT013492 Interleukin-13 receptor subunit alpha-2 3598 reviewed Signaling
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 1244 reviewed Transporter
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q9NXG6 BXGT021246 Transmembrane prolyl 4-hydroxylase 54681 reviewed
Q9UHC9 BXGT021696 NPC1-like intracellular cholesterol transporter 1 29881 reviewed Transporter
Q9Y3D6 BXGT022257 Mitochondrial fission 1 protein 51024 reviewed
Q9Y6K9 BXGT022333 NF-kappa-B essential modulator 8517 reviewed Kinase
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease