adisease

Showing entry for Ischemia

General Disease Information
BXGD Id	BXGD001531
Disease Name	Ischemia
Disease CUI Id	C0022116
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Pathologic Function
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14684	BXGT004082	Prostaglandin E synthase	9536	reviewed
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O95069	BXGT005348	Potassium channel subfamily K member 2	3776	reviewed	Ion channel
O95178	BXGT005357	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial	4708	reviewed
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P00749	BXGT005641	Urokinase-type plasminogen activator	5328	reviewed	Enzyme
P00750	BXGT005642	Tissue-type plasminogen activator	5327	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P04083	BXGT006147	Annexin A1	301	reviewed
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06732	BXGT006489	Creatine kinase M-type	1158	reviewed	Kinase
P06756	BXGT006499	Integrin alpha-V	3685	reviewed
P06870	BXGT006518	Kallikrein-1	3816	reviewed	Enzyme
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P08047	BXGT006720	Transcription factor Sp1	6667	reviewed	Nucleic acid binding
P08138	BXGT006729	Tumor necrosis factor receptor superfamily member 16	4804	reviewed	Receptor
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08758	BXGT006821	Annexin A5	308	reviewed
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P0DMS8	BXGT007506	Adenosine receptor A3	140	reviewed	G-protein coupled receptor
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14151	BXGT007990	L-selectin	6402	reviewed
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15121	BXGT008083	Aldo-keto reductase family 1 member B1	231	reviewed	Enzyme
P16581	BXGT008245	E-selectin	6401	reviewed
P17252	BXGT008294	Protein kinase C alpha type	5578	reviewed	Kinase
P18146	BXGT008384	Early growth response protein 1	1958	reviewed	Nucleic acid binding
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19634	BXGT008504	Sodium/hydrogen exchanger 1	6548	reviewed	Transporter
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P26447	BXGT009114	Protein S100-A4	6275	reviewed	Calcium-binding protein
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P28222	BXGT009238	5-hydroxytryptamine receptor 1B	3351	reviewed	G-protein coupled receptor
P29033	BXGT009308	Gap junction beta-2 protein	2706	reviewed	Cell-cell junction
P29274	BXGT009327	Adenosine receptor A2a	135	reviewed	G-protein coupled receptor
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P30542	BXGT009436	Adenosine receptor A1	134	reviewed	G-protein coupled receptor
P31751	BXGT009576	RAC-beta serine/threonine-protein kinase	208	reviewed	Kinase
P32418	BXGT009635	Sodium/calcium exchanger 1	6546	reviewed	Transporter
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P45984	BXGT010495	Mitogen-activated protein kinase 9	5601	reviewed	Kinase
P47989	BXGT010602	Xanthine dehydrogenase/oxidase	7498	reviewed	Enzyme
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P50052	BXGT010768	Type-2 angiotensin II receptor	186	reviewed	G-protein coupled receptor
P50281	BXGT010788	Matrix metalloproteinase-14	4323	reviewed	Enzyme
P62736	BXGT011452	Actin, aortic smooth muscle	59	reviewed	Cellular structure
P80404	BXGT011907	4-aminobutyrate aminotransferase, mitochondrial	18	reviewed	Enzyme
P99999	BXGT012235	Cytochrome c	54205	reviewed
Q05397	BXGT012815	Focal adhesion kinase 1	5747	reviewed	Kinase
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q07817	BXGT012941	Bcl-2-like protein 1	598	reviewed	Signaling
Q08722	BXGT013002	Leukocyte surface antigen CD47	961	reviewed
Q13324	BXGT013340	Corticotropin-releasing factor receptor 2	1395	reviewed	G-protein coupled receptor
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14457	BXGT013472	Beclin-1	8678	reviewed	Enzyme modulator
Q14524	BXGT013478	Sodium channel protein type 5 subunit alpha	6331	reviewed	Ion channel
Q15637	BXGT013586	Splicing factor 1	7536	reviewed	Nucleic acid binding
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q7RTT9	BXGT017086	Equilibrative nucleoside transporter 4	222962	reviewed	Transporter
Q8NFD5	BXGT018560	AT-rich interactive domain-containing protein 1B	57492	reviewed
Q99538	BXGT019931	Legumain	5641	reviewed	Enzyme
Q9H492	BXGT020472	Microtubule-associated proteins 1A/1B light chain 3A	84557	reviewed	Cellular structure

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}