Showing entry for Sodium channel protein type 5 subunit alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013478
Protein NameSodium channel protein type 5 subunit alpha
Uniport IdQ14524
GeneSCN5A
Gene Id6331
DomainIon_trans; Na_trans_assoc; Na_trans_cytopl
Pfam PF00520   PF06512   PF11933  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.3 Circulatory system hsa04261 Adrenergic signaling in cardiomyocytes
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0086014 atrial cardiac muscle cell action potential
Biological Process GO:0086016 AV node cell action potential
Biological Process GO:0086067 AV node cell to bundle of His cell communication
Biological Process GO:0003360 brainstem development
Biological Process GO:0086043 bundle of His cell action potential
Biological Process GO:0061337 cardiac conduction
Biological Process GO:0086002 cardiac muscle cell action potential involved in contraction
Biological Process GO:0060048 cardiac muscle contraction
Biological Process GO:0003231 cardiac ventricle development
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:0021549 cerebellum development
Biological Process GO:0051899 membrane depolarization
Biological Process GO:0086010 membrane depolarization during action potential
Biological Process GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential
Biological Process GO:0086045 membrane depolarization during AV node cell action potential
Biological Process GO:0086048 membrane depolarization during bundle of His cell action potential
Biological Process GO:0086012 membrane depolarization during cardiac muscle cell action potential
Biological Process GO:0086047 membrane depolarization during Purkinje myocyte cell action potential
Biological Process GO:0086046 membrane depolarization during SA node cell action potential
Biological Process GO:0019228 neuronal action potential
Biological Process GO:0042475 odontogenesis of dentin-containing tooth
Biological Process GO:0045760 positive regulation of action potential
Biological Process GO:0050679 positive regulation of epithelial cell proliferation
Biological Process GO:0010765 positive regulation of sodium ion transport
Biological Process GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization
Biological Process GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization
Biological Process GO:0086004 regulation of cardiac muscle cell contraction
Biological Process GO:0002027 regulation of heart rate
Biological Process GO:0086091 regulation of heart rate by cardiac conduction
Biological Process GO:1902305 regulation of sodium ion transmembrane transport
Biological Process GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization
Biological Process GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization
Biological Process GO:0014894 response to denervation involved in regulation of muscle adaptation
Biological Process GO:0086015 SA node cell action potential
Biological Process GO:0035725 sodium ion transmembrane transport
Biological Process GO:0006814 sodium ion transport
Biological Process GO:0021537 telencephalon development
Biological Process GO:0086005 ventricular cardiac muscle cell action potential
molecular function GO:0030506 ankyrin binding
molecular function GO:0005516 calmodulin binding
molecular function GO:0005261 cation channel activity
molecular function GO:0019899 enzyme binding
molecular function GO:0017134 fibroblast growth factor binding
molecular function GO:0044325 ion channel binding
molecular function GO:0050998 nitric-oxide synthase binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0097110 scaffold protein binding
molecular function GO:0031625 ubiquitin protein ligase binding
molecular function GO:0005244 voltage-gated ion channel activity
molecular function GO:0005248 voltage-gated sodium channel activity
molecular function GO:0086060 voltage-gated sodium channel activity involved in AV node cell action potential
molecular function GO:0086061 voltage-gated sodium channel activity involved in bundle of His cell action potential
molecular function GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential
molecular function GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential
molecular function GO:0086063 voltage-gated sodium channel activity involved in SA node cell action potential
cellular component GO:0005901 caveola
cellular component GO:0009986 cell surface
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0016021 integral component of membrane
cellular component GO:0014704 intercalated disc
cellular component GO:0016328 lateral plasma membrane
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0042383 sarcolemma
cellular component GO:0030315 T-tubule
cellular component GO:0001518 voltage-gated sodium channel complex
cellular component GO:0030018 Z disc
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-373760 L1CAM interactions
R-HSA-397014 Muscle contraction
R-HSA-422475 Axon guidance
R-HSA-445095 Interaction between L1 and Ankyrins
R-HSA-5576891 Cardiac conduction
R-HSA-5576892 Phase 0 - rapid depolarisation
R-HSA-9675108 Nervous system development
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000737 BXGD000005 Abdominal Pain Pathological Conditions, Signs and Symptoms
C0000772 BXGD000009 Multiple congenital anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001127 BXGD000026 Acidosis, Respiratory Nutritional and Metabolic Diseases; Respiratory Tract Diseases
C0002792 BXGD000129 anaphylaxis Immune System Diseases
C0002962 BXGD000160 Angina Pectoris Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003886 BXGD000238 Arthrogryposis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004239 BXGD000263 Atrial Flutter Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004245 BXGD000264 Atrioventricular Block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0005859 BXGD000342 Bloom Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0005904 BXGD000348 Body Temperature Changes Pathological Conditions, Signs and Symptoms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006384 BXGD000395 Bundle-Branch Block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007193 BXGD000451 Cardiomyopathy, Dilated Cardiovascular Diseases
C0007194 BXGD000452 Hypertrophic Cardiomyopathy Cardiovascular Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0008928 BXGD000576 Cleidocranial Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0011071 BXGD000696 Sudden death Pathological Conditions, Signs and Symptoms
C0013363 BXGD000818 Dysautonomia Nervous System Diseases
C0013404 BXGD000833 Dyspnea Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0018794 BXGD001222 Heart Block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0018798 BXGD001223 Congenital Heart Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0018799 BXGD001224 Heart Diseases Cardiovascular Diseases
C0018800 BXGD001225 Cardiomegaly Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018803 BXGD001228 Heart Function Tests
C0020621 BXGD001449 Hypokalemia Nutritional and Metabolic Diseases
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0022116 BXGD001531 Ischemia Pathological Conditions, Signs and Symptoms
C0022387 BXGD001543 Jervell-Lange Nielsen Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0023211 BXGD001615 Left Bundle-Branch Block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0023787 BXGD001698 Lipodystrophy Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0023976 BXGD001724 Long QT Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0024591 BXGD001789 Malignant hyperpyrexia due to anesthesia Pathological Conditions, Signs and Symptoms
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027126 BXGD001976 Myotonic Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027831 BXGD002047 Neurofibromatosis 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0027859 BXGD002052 Acoustic Neuroma Neoplasms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0030252 BXGD002199 Palpitations Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0030591 BXGD002247 Paroxysmal ventricular tachycardia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0033036 BXGD002389 Atrial Premature Complexes Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0035828 BXGD002566 Romano-Ward Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037052 BXGD002662 Sick Sinus Syndrome Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038644 BXGD002776 Sudden infant death syndrome Pathological Conditions, Signs and Symptoms
C0039070 BXGD002787 Syncope Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0039231 BXGD002799 Tachycardia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0039240 BXGD002804 Supraventricular tachycardia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0040479 BXGD002870 Torsades de Pointes Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0041408 BXGD002923 Turner Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0042420 BXGD002982 Vasovagal syncope Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0042510 BXGD002987 Ventricular Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0042514 BXGD002989 Tachycardia, Ventricular Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0042571 BXGD002991 Vertigo Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0043202 BXGD003037 Wolff-Parkinson-White Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0079035 BXGD003061 Bradyarrhythmia (disorder) Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085298 BXGD003155 Sudden Cardiac Death Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085610 BXGD003202 Sinus bradycardia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0085612 BXGD003204 Ventricular arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085614 BXGD003205 First degree atrioventricular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085615 BXGD003206 Right bundle branch block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0151636 BXGD003451 Premature ventricular contractions Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0151878 BXGD003495 Prolonged QT interval Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0152021 BXGD003520 Congenital heart disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0155707 BXGD003813 Trifascicular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0155708 BXGD003814 Other specified conduction disorders Cardiovascular Diseases
C0162678 BXGD003974 Neurofibromatoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0221047 BXGD004379 Bradycardia-tachycardia syndrome Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0232197 BXGD004536 Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0232216 BXGD004537 Ventricular escape rhythm
C0235480 BXGD004751 Paroxysmal atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0241005 BXGD005072 Creatine phosphokinase serum increased
C0264694 BXGD005413 Chronic myocardial ischemia Cardiovascular Diseases
C0264886 BXGD005432 Conduction disorder of the heart Cardiovascular Diseases
C0264893 BXGD005433 Nodal rhythm disorder Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0264912 BXGD005435 Left anterior fascicular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0264913 BXGD005436 Left posterior fascicular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0268095 BXGD005814 Keshan disease Infections; Cardiovascular Diseases
C0268450 BXGD005951 Gitelman Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0340427 BXGD007329 Familial dilated cardiomyopathy Cardiovascular Diseases
C0340464 BXGD007332 Premature Cardiac Complex Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0340486 BXGD007335 Induced ventricular tachycardia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0340489 BXGD007336 Lone atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0340491 BXGD007337 Familial sick sinus syndrome Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0340493 BXGD007338 Paroxysmal familial ventricular fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0340850 BXGD007371 Neurally mediated syncope Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0344432 BXGD007670 Ventricular tachycardia, polymorphic Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0348626 BXGD007878 Other specified cardiac arrhythmias Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0349788 BXGD007956 Arrhythmogenic Right Ventricular Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0391957 BXGD008019 idiopathic epilepsy
C0410000 BXGD008406 Overlap syndrome Skin and Connective Tissue Diseases; Immune System Diseases
C0426576 BXGD008571 Gastrointestinal symptom Pathological Conditions, Signs and Symptoms
C0427515 BXGD008619 Neutrophil abnormality
C0428908 BXGD008641 Sinus Node Dysfunction (disorder) Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0428974 BXGD008642 Supraventricular arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0428977 BXGD008644 Bradycardia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0429021 BXGD008645 P wave duration (observable entity)
C0429028 BXGD008646 QT interval feature (observable entity)
C0429087 BXGD008647 Electrocardiogram: P-R interval
C0429097 BXGD008648 QRS complex feature
C0476403 BXGD008992 Electromyogram abnormal
C0520886 BXGD009118 ST segment elevation (finding) Cardiovascular Diseases
C0541782 BXGD009261 Atrial standstill Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0546959 BXGD009347 Atrial tachycardia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0685108 BXGD009806 Lenegre's disease Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0694539 BXGD009849 Chronic atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0741916 BXGD010044 Cardiac defects
C0741923 BXGD010045 cardiac event
C0743841 BXGD010085 Disorder characterized by fever Pathological Conditions, Signs and Symptoms
C0748061 BXGD010189 psychiatric hospitalization
C0748607 BXGD010201 Recurrent seizure Nervous System Diseases
C0748694 BXGD010202 sick sinus
C0750194 BXGD010230 Non-sustained ventricular tachycardia
C0751534 BXGD010494 Syncopal Episode Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751951 BXGD010648 Central Core Myopathy (disorder) Musculoskeletal Diseases; Nervous System Diseases
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0855329 BXGD011084 Electrocardiogram change
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C1096378 BXGD011619 Near sudden infant death syndrome
C1141890 BXGD011721 Congenital long QT syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1142166 BXGD011736 Brugada Syndrome (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1280433 BXGD012125 Lipoatrophy Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C1397307 BXGD012996 Cardiac fibrosis
C1399226 BXGD013003 Ectopic rhythm Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1536220 BXGD013341 ST segment elevation myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1560249 BXGD013361 Adverse Event Associated with Cardiac Arrhythmia
C1560305 BXGD013362 Prolonged QTc interval
C1563715 BXGD013389 Andersen Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1611743 BXGD013456 Familial (FPAH)
C1623258 BXGD013476 Electrocardiography
C1631597 BXGD013480 VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder) Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1704431 BXGD013563 Disorder of electrolytes Nutritional and Metabolic Diseases
C1720983 BXGD013698 Channelopathies Pathological Conditions, Signs and Symptoms
C1721096 BXGD013704 Brugada ECG Pattern Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1821417 BXGD013764 RESTING HEART RATE
C1828221 BXGD013786 Non dystrophic myotonia Musculoskeletal Diseases; Nervous System Diseases
C1832680 BXGD013870 CARDIOMYOPATHY, DILATED, 1E Cardiovascular Diseases
C1837845 BXGD014281 SICK SINUS SYNDROME 1, AUTOSOMAL RECESSIVE Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1838527 BXGD014317 LONG QT SYNDROME 3, ACQUIRED, SUSCEPTIBILITY TO (finding)
C1838539 BXGD014318 CARDIOMYOPATHY, FAMILIAL, WITH CONDUCTION DISTURBANCE Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1839341 BXGD014370 Abnormal T-wave
C1843687 BXGD014602 ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1857276 BXGD015688 Trichohepatoenteric Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C1858379 BXGD015785 ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA, FAMILIAL, 5 (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1858430 BXGD015792 Death in infancy
C1859062 BXGD015847 LONG QT SYNDROME 3 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1861983 BXGD016096 Heart Block, Nonprogressive Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1861984 BXGD016097 Cardiac Conduction Defect, Nonprogressive Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1879286 BXGD016570 Hereditary bundle branch system defect Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1960469 BXGD016664 Left ventricular noncompaction Cardiovascular Diseases
C1963175 BXGD016687 Sinus Bradycardia, CTCAE
C1963217 BXGD016689 Prolonged QTc Interval, CTCAE
C2063326 BXGD016902 Right ventricular cardiomyopathy Cardiovascular Diseases
C2108107 BXGD016920 continuous electrocardiogram sinus bradycardia (finding)
C2114320 BXGD016925 preterm contractions
C2215995 BXGD016947 electrocardiogram - left anterior hemiblock
C2216002 BXGD016948 electrocardiogram left posterior hemiblock (finding)
C2584409 BXGD017126 Prothrombin G20210A mutation Hemic and Lymphatic Diseases
C2585653 BXGD017139 Persistent atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C2678485 BXGD017420 LONG QT SYNDROME 9 (disorder) Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C2721586 BXGD017538 Sudden arrhythmic death syndrome Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C2732979 BXGD017560 Acquired long QT syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C2748542 BXGD017596 CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C2751898 BXGD017749 Ventricular Fibrillation, Paroxysmal Familial, 1 Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C2930805 BXGD017895 Sudden unexpected nocturnal death syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C2931401 BXGD018017 Long QT syndrome type 3 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C2931783 BXGD018061 Amelogenesis imperfecta nephrocalcinosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Stomatognathic Diseases
C3150852 BXGD018342 EARLY REPOLARIZATION ASSOCIATED WITH VENTRICULAR FIBRILLATION
C3150943 BXGD018362 Long Qt Syndrome 2 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C3151464 BXGD018432 ATRIAL FIBRILLATION, FAMILIAL, 10
C3151520 BXGD018439 Early severe fetal akinesia sequence
C3160712 BXGD018467 Palpitations, CTCAE
C3250443 BXGD018584 MYOTONIC DYSTROPHY 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3276240 BXGD018687 LONG QT SYNDROME 2/3, DIGENIC
C3276241 BXGD018688 LONG QT SYNDROME 3/6, DIGENIC Disorder
C3468561 BXGD018908 familial atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C3698186 BXGD019366 Cardiac channelopathy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C3715208 BXGD019451 AV Block First Degree by ECG Finding Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C3807980 BXGD019534 Apneic episodes in infancy Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C3814825 BXGD019670 Sudden Unexplained Infant Death Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C4016652 BXGD020354 ATRIAL STANDSTILL 1, DIGENIC
C4017668 BXGD020456 VENTRICULAR FIBRILLATION DURING MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO
C4021133 BXGD020563 Left ventricular noncompaction cardiomyopathy Pathological Conditions, Signs and Symptoms
C4022012 BXGD020868 Death in early adulthood
C4025008 BXGD021523 Reduced systolic function Cardiovascular Diseases
C4025797 BXGD021795 Abnormality of prenatal development or birth
C4285910 BXGD022462 Obstructive sleep apnea hypopnea syndrome
C4476543 BXGD022825 Complete heart block with broad QRS complexes
C4477077 BXGD022917 Abnormal cardiac exercise stress test
C4551647 BXGD023381 Long QT Syndrome 1 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4551675 BXGD023384 Keratoderma, Palmoplantar Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C4551804 BXGD023411 Brugada Syndrome 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4551959 BXGD023450 ATRIAL STANDSTILL 1 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0024988 Nifedipine 346.12
BXGC0035201 Quinidine 324.18
BXGC0042114 Solifenacin 362.2
BXGC0042222 Propranolol 259.16
BXGC0044017 Verapamil 454.28
BXGC0049369 Tetrodotoxin 319.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein