Showing entry for Liver Cirrhosis, Alcoholic


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001714
Disease NameLiver Cirrhosis, Alcoholic
Disease CUI IdC0023891
MeSH Codes C23   C06   C25  
Disease Class NamePathological Conditions, Signs and Symptoms; Digestive System Diseases; Chemically-Induced Disorders
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O14594 BXGT004073 Neurocan core protein 1463 reviewed Extracellular structure
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O95750 BXGT005395 Fibroblast growth factor 19 9965 reviewed Signaling
P00325 BXGT005498 Alcohol dehydrogenase 1B 125 reviewed Enzyme
P00326 BXGT005499 Alcohol dehydrogenase 1C 126 reviewed Enzyme
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P02461 BXGT005880 Collagen alpha-1(III) chain 1281 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05089 BXGT006310 Arginase-1 383 reviewed Enzyme
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05181 BXGT006337 Cytochrome P450 2E1 1571 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08319 BXGT006764 Alcohol dehydrogenase 4 127 reviewed Enzyme
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11766 BXGT007745 Alcohol dehydrogenase class-3 128 reviewed Enzyme
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13236 BXGT007891 C-C motif chemokine 4 6351 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14550 BXGT008019 Aldo-keto reductase family 1 member A1 10327 reviewed Enzyme
P14616 BXGT008026 Insulin receptor-related protein 3645 reviewed Kinase
P15104 BXGT008081 Glutamine synthetase 2752 reviewed Enzyme
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16581 BXGT008245 E-selectin 6401 reviewed
P18507 BXGT008411 Gamma-aminobutyric acid receptor subunit gamma-2 2566 reviewed Ion channel
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19440 BXGT008481 Glutathione hydrolase 1 proenzyme 2678 reviewed Enzyme
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P29508 BXGT009358 Serpin B3 6317 reviewed Enzyme modulator
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43004 BXGT010348 Excitatory amino acid transporter 2 6506 reviewed Transporter
P43652 BXGT010405 Afamin 173 reviewed Transporter
P45452 BXGT010462 Collagenase 3 4322 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P62993 BXGT011480 Growth factor receptor-bound protein 2 2885 reviewed
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q00266 BXGT012515 S-adenosylmethionine synthase isoform type-1 4143 reviewed Enzyme
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q02928 BXGT012680 Cytochrome P450 4A11 1579 reviewed Enzyme
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q13137 BXGT013316 Calcium-binding and coiled-coil domain-containing protein 2 10241 reviewed
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q9NRA0 BXGT021183 Sphingosine kinase 2 56848 reviewed Kinase
Q9Y572 BXGT022289 Receptor-interacting serine/threonine-protein kinase 3 11035 reviewed Kinase
Q9Y6X2 BXGT022343 E3 SUMO-protein ligase PIAS3 10401 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease