Showing entry for Neurocan core protein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004073
Protein NameNeurocan core protein
Uniport IdO14594
GeneNCAN
Gene Id1463
DomainEGF; Lectin_C; Sushi; V-set; Xlink
Pfam PF00008   PF00059   PF00084   PF07686   PF00193  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007155 cell adhesion
Biological Process GO:0007417 central nervous system development
Biological Process GO:0030206 chondroitin sulfate biosynthetic process
Biological Process GO:0030207 chondroitin sulfate catabolic process
Biological Process GO:0030208 dermatan sulfate biosynthetic process
Biological Process GO:0030198 extracellular matrix organization
Biological Process GO:0001501 skeletal system development
molecular function GO:0005509 calcium ion binding
molecular function GO:0030246 carbohydrate binding
molecular function GO:0005540 hyaluronic acid binding
cellular component GO:0031012 extracellular matrix
cellular component GO:0005576 extracellular region
cellular component GO:0005796 Golgi lumen
cellular component GO:0043202 lysosomal lumen
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-1430728 Metabolism
R-HSA-1474244 Extracellular matrix organization
R-HSA-1630316 Glycosaminoglycan metabolism
R-HSA-1638091 Heparan sulfate/heparin (HS-GAG) metabolism
R-HSA-1643685 Disease
R-HSA-1793185 Chondroitin sulfate/dermatan sulfate metabolism
R-HSA-1971475 A tetrasaccharide linker sequence is required for GAG synthesis
R-HSA-2022870 Chondroitin sulfate biosynthesis
R-HSA-2022923 Dermatan sulfate biosynthesis
R-HSA-2024101 CS/DS degradation
R-HSA-3000178 ECM proteoglycans
R-HSA-3560782 Diseases associated with glycosaminoglycan metabolism
R-HSA-3560783 Defective B4GALT7 causes EDS, progeroid type
R-HSA-3560801 Defective B3GAT3 causes JDSSDHD
R-HSA-3595172 Defective CHST3 causes SEDCJD
R-HSA-3595174 Defective CHST14 causes EDS, musculocontractural type
R-HSA-3595177 Defective CHSY1 causes TPBS
R-HSA-373760 L1CAM interactions
R-HSA-375165 NCAM signaling for neurite out-growth
R-HSA-3781865 Diseases of glycosylation
R-HSA-419037 NCAM1 interactions
R-HSA-422475 Axon guidance
R-HSA-4420332 Defective B3GALT6 causes EDSP2 and SEMDJL1
R-HSA-5668914 Diseases of metabolism
R-HSA-71387 Metabolism of carbohydrates
R-HSA-9675108 Nervous system development
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005587 BXGD000316 Depression, Bipolar Mental Disorders
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006111 BXGD000369 Brain Diseases Nervous System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0023891 BXGD001714 Liver Cirrhosis, Alcoholic Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Chemically-Induced Disorders
C0023896 BXGD001718 Alcoholic Liver Diseases Digestive System Diseases; Chemically-Induced Disorders
C0024713 BXGD001799 Manic Disorder Mental Disorders
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028756 BXGD002083 Obesity, Morbid Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0085762 BXGD003251 Alcohol abuse Chemically-Induced Disorders; Mental Disorders
C0162309 BXGD003934 Adrenoleukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C0201657 BXGD004051 C-reactive protein measurement
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0202236 BXGD004086 Triglycerides measurement
C0234213 BXGD004632 Sensory denervation disorder
C0236773 BXGD004827 Depressed bipolar I disorder Mental Disorders
C0338831 BXGD007216 Manic Mental Disorders
C0392885 BXGD008071 High density lipoprotein measurement
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0428474 BXGD008631 Serum LDL cholesterol measurement
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0920296 BXGD011464 Developmental reading disorder Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C1148477 BXGD011765 Deafness, Sudden Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1262048 BXGD011866 Glial scar
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1445957 BXGD013081 Serum total cholesterol measurement
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2047886 BXGD016892 (Idiopathic) normal pressure hydrocephalus Nervous System Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005620 beta-D-Glucopyranose 180.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein