Showing entry for Lysozyme C


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011382
Protein NameLysozyme C
Uniport IdP61626
GeneLYZ
Gene Id4069
DomainLys
Pfam PF00062  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.4 Digestive system hsa04970 Salivary secretion
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019730 antimicrobial humoral response
Biological Process GO:0044267 cellular protein metabolic process
Biological Process GO:0019835 cytolysis
Biological Process GO:0042742 defense response to bacterium
Biological Process GO:0050829 defense response to Gram-negative bacterium
Biological Process GO:0050830 defense response to Gram-positive bacterium
Biological Process GO:0006954 inflammatory response
Biological Process GO:0031640 killing of cells of other organism
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0001895 retina homeostasis
molecular function GO:0042802 identical protein binding
molecular function GO:0003796 lysozyme activity
cellular component GO:0035578 azurophil granule lumen
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0035580 specific granule lumen
cellular component GO:1904724 tertiary granule lumen
Reactome
Pathway Id Pathway Name
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-392499 Metabolism of proteins
R-HSA-6798695 Neutrophil degranulation
R-HSA-6803157 Antimicrobial peptides
R-HSA-977225 Amyloid fiber formation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001144 BXGD000028 Acne Vulgaris Skin and Connective Tissue Diseases
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0002792 BXGD000129 anaphylaxis Immune System Diseases
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0003125 BXGD000179 Anorexia Nervosa Mental Disorders
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0003962 BXGD000244 Ascites Pathological Conditions, Signs and Symptoms
C0004059 BXGD000250 aspirin intolerance
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0004943 BXGD000297 Behcet Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Stomatognathic Diseases; Cardiovascular Diseases
C0005699 BXGD000325 Blast Phase Pathological Conditions, Signs and Symptoms; Neoplasms; Hemic and Lymphatic Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006849 BXGD000413 Oral candidiasis Infections; Stomatognathic Diseases
C0007570 BXGD000467 Celiac Disease Digestive System Diseases; Nutritional and Metabolic Diseases
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0010278 BXGD000660 Craniosynostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010606 BXGD000677 Adenoid Cystic Carcinoma Neoplasms
C0010930 BXGD000691 Dacryocystitis Eye Diseases
C0011175 BXGD000701 Dehydration Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0012546 BXGD000776 Diphtheria Infections
C0013371 BXGD000823 Shigella Infections Digestive System Diseases; Infections
C0013604 BXGD000859 Edema Pathological Conditions, Signs and Symptoms
C0014335 BXGD000908 Enteritis Digestive System Diseases
C0015230 BXGD000969 Exanthema Skin and Connective Tissue Diseases
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0017152 BXGD001096 Gastritis Digestive System Diseases
C0017178 BXGD001102 Gastrointestinal Diseases Digestive System Diseases
C0017574 BXGD001122 Gingivitis Infections; Stomatognathic Diseases
C0017638 BXGD001132 Glioma Neoplasms
C0018213 BXGD001187 Graves Disease Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0018621 BXGD001210 Hay fever Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C0018965 BXGD001258 Hematuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0019621 BXGD001340 Histiocytosis, Langerhans-Cell Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0019624 BXGD001342 Histiocytosis, Non-Langerhans-Cell Hemic and Lymphatic Diseases
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020473 BXGD001396 Hyperlipidemia Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020877 BXGD001471 Ileitis Digestive System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021831 BXGD001516 Intestinal Diseases Digestive System Diseases
C0022354 BXGD001540 Jaundice, Obstructive Pathological Conditions, Signs and Symptoms
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023480 BXGD001664 Leukemia, Myelomonocytic, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023508 BXGD001675 White Blood Cell Count procedure
C0023532 BXGD001685 Leukoplakia, Oral Pathological Conditions, Signs and Symptoms; Neoplasms; Stomatognathic Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024894 BXGD001810 Mastitis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C0025289 BXGD001851 Meningitis Nervous System Diseases
C0026837 BXGD001937 Muscle Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027726 BXGD002030 Nephrotic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030524 BXGD002236 Paratuberculosis Infections; Animal Diseases
C0031069 BXGD002279 Familial Mediterranean Fever Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0031090 BXGD002280 Periodontal Diseases Stomatognathic Diseases
C0031117 BXGD002285 Peripheral Neuropathy Nervous System Diseases
C0031256 BXGD002296 Petechiae Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Cardiovascular Diseases
C0033687 BXGD002415 Proteinuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0035078 BXGD002505 Kidney Failure Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0036202 BXGD002581 Sarcoidosis Hemic and Lymphatic Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0037284 BXGD002679 Skin lesion Skin and Connective Tissue Diseases
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0038436 BXGD002755 Post-Traumatic Stress Disorder Mental Disorders
C0041296 BXGD002903 Tuberculosis Infections
C0041327 BXGD002916 Tuberculosis, Pulmonary Infections; Respiratory Tract Diseases
C0041912 BXGD002937 Upper Respiratory Infections Infections; Respiratory Tract Diseases
C0041956 BXGD002942 Ureteral obstruction Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042842 BXGD003005 Vitamin A Deficiency Nutritional and Metabolic Diseases
C0085166 BXGD003136 Bacterial Vaginosis Female Urogenital Diseases and Pregnancy Complications; Infections
C0085859 BXGD003254 Polyglandular Type I Autoimmune Syndrome Immune System Diseases; Endocrine System Diseases
C0086981 BXGD003317 Sicca Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C0149516 BXGD003324 Chronic sinusitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0149725 BXGD003351 Lower respiratory tract infection Infections; Respiratory Tract Diseases
C0149745 BXGD003356 Oral Ulcer Stomatognathic Diseases
C0156147 BXGD003838 Crohn's disease of large bowel Digestive System Diseases
C0178238 BXGD004020 Intestinal infectious disease (disorder) Digestive System Diseases; Infections
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0200637 BXGD004042 Monocyte count procedure
C0206062 BXGD004148 Lung Diseases, Interstitial Respiratory Tract Diseases
C0206685 BXGD004240 Acinar Cell Carcinoma Neoplasms
C0221106 BXGD004390 Alkalemia
C0221271 BXGD004431 Elastosis perforans serpiginosa Skin and Connective Tissue Diseases
C0232197 BXGD004536 Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0232487 BXGD004546 Abdominal discomfort Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0232491 BXGD004548 Chronic abdominal pain Pathological Conditions, Signs and Symptoms
C0236734 BXGD004823 Caffeine related disorders
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0238621 BXGD004947 Aminoaciduria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0241144 BXGD005080 Petechiae of skin Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0267380 BXGD005743 Crohn's disease of the ileum Digestive System Diseases
C0267537 BXGD005756 Typhlitis Digestive System Diseases; Infections
C0267941 BXGD005793 Pancreatitis, Acute Necrotizing Digestive System Diseases
C0268380 BXGD005921 Systemic amyloidosis Nutritional and Metabolic Diseases
C0268382 BXGD005923 Amyloid nephropathy Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0268384 BXGD005925 Familial Amyloid Neuropathy, Portuguese Type Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0268389 BXGD005928 Amyloidosis, familial visceral Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0268731 BXGD006029 Renal glomerular disease Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0272170 BXGD006312 Shwachman syndrome
C0275524 BXGD006376 Coinfection Infections
C0281479 BXGD006776 Primary Systemic Amyloidosis Neoplasms; Nutritional and Metabolic Diseases; Immune System Diseases
C0334347 BXGD007039 Eccrine spiradenoma Neoplasms
C0334463 BXGD007076 Malignant Fibrous Histiocytoma Neoplasms
C0334663 BXGD007149 Histiocytic sarcoma Neoplasms; Hemic and Lymphatic Diseases
C0339143 BXGD007226 Thyroid associated opthalmopathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0343401 BXGD007623 MRSA - Methicillin resistant Staphylococcus aureus infection Infections
C0376618 BXGD008003 Endotoxemia Pathological Conditions, Signs and Symptoms; Infections
C0399452 BXGD008247 Supragingival dental plaque Stomatognathic Diseases
C0426576 BXGD008571 Gastrointestinal symptom Pathological Conditions, Signs and Symptoms
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0519002 BXGD009076 Gastrointestinal amyloidosis Nutritional and Metabolic Diseases
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0559469 BXGD009470 Allergy to eggs Immune System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0702166 BXGD009912 Acne Skin and Connective Tissue Diseases
C0740340 BXGD009978 Amyloidosis, Familial Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0743746 BXGD010084 eyes dry chronic
C0750880 BXGD010239 Monocyte count result
C0854135 BXGD011002 Pseudomonas aeruginosa infection Infections
C0860659 BXGD011240 Aloof
C0876973 BXGD011322 Infectious Lung Disorder Infections; Respiratory Tract Diseases
C0947751 BXGD011494 Vascular inflammations Cardiovascular Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1334655 BXGD012723 Mediastinal Germ Cell Tumor Neoplasms; Respiratory Tract Diseases
C1411966 BXGD013047 Clostridium; difficile (disorder)
C1510420 BXGD013158 Cavitation
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1535510 BXGD013319 ADENOMAS AND ADENOCARCINOMAS Neoplasms
C1608408 BXGD013434 Malignant transformation
C1611743 BXGD013456 Familial (FPAH)
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1862968 BXGD016146 Generalized amyloid deposition Nutritional and Metabolic Diseases
C1868684 BXGD016527 EAR, PATELLA, SHORT STATURE SYNDROME Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2936349 BXGD018109 Plaque, Amyloid Pathological Conditions, Signs and Symptoms
C2985280 BXGD018223 Blood Protein Measurement
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3495559 BXGD018994 Juvenile arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3539920 BXGD019089 ECTODERMAL DYSPLASIA 11B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL RECESSIVE
C3541517 BXGD019097 ECTODERMAL DYSPLASIA 11A, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL DOMINANT
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3887494 BXGD019881 ECTODERMAL DYSPLASIA 10B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL RECESSIVE Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C3888065 BXGD019946 ECTODERMAL DYSPLASIA 10A, HYPOHIDROTIC/HAIR/NAIL TYPE, AUTOSOMAL DOMINANT
C4048329 BXGD021904 Immunosuppression
C4081731 BXGD022080 Hereditary systemic amyloidosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C4529962 BXGD023178 Fatty Liver Disease
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
C4721505 BXGD023746 Sarcoma, Myeloid Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000989 Glutathione 307.32
BXGC0002586 Calcium 40.08
BXGC0002675 Sugars 342.3
BXGC0002722 Nitrate 62
BXGC0003705 Chloride 35.45
BXGC0004264 1-Propanol 60.1
BXGC0006186 L-Aspartic acid 133.1
BXGC0006271 L-Cysteine 121.16
BXGC0018397 beta-1,4-mannan 180.06
BXGC0033112 Acetylcysteine 163.03
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein