Showing entry for Paraparesis, Spastic


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002702
Disease NameParaparesis, Spastic
Disease CUI IdC0037771
MeSH Codes C23   C10  
Disease Class NamePathological Conditions, Signs and Symptoms; Nervous System Diseases
Semantic TypeSign or Symptom
Human Phenotype Ontology Id HP:0000707   HP:0003011  
Human Phenotype Ontology TermAbnormality of the nervous system; Abnormality of the musculature
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O43896 BXGT004632 Kinesin-like protein KIF1C 10749 reviewed Cellular structure
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04156 BXGT006156 Major prion protein 5621 reviewed
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P07384 BXGT006619 Calpain-1 catalytic subunit 823 reviewed Enzyme
P10809 BXGT007617 60 kDa heat shock protein, mitochondrial 3329 reviewed
P23415 BXGT008864 Glycine receptor subunit alpha-1 2741 reviewed Ion channel
P24530 BXGT008975 Endothelin receptor type B 1910 reviewed G-protein coupled receptor
P31040 BXGT009503 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 6389 reviewed Enzyme
P35475 BXGT009837 Alpha-L-iduronidase 3425 reviewed Enzyme
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
P54762 BXGT011076 Ephrin type-B receptor 1 2047 reviewed Kinase
P54886 BXGT011092 Delta-1-pyrroline-5-carboxylate synthase 5832 reviewed Enzyme
P55265 BXGT011117 Double-stranded RNA-specific adenosine deaminase 103 reviewed Enzyme
Q12756 BXGT013261 Kinesin-like protein KIF1A 547 reviewed Cellular structure
Q12840 BXGT013269 Kinesin heavy chain isoform 5A 3798 reviewed Cellular structure
Q6XUX3 BXGT016612 Dual serine/threonine and tyrosine protein kinase 25778 reviewed Kinase
Q99447 BXGT019922 Ethanolamine-phosphate cytidylyltransferase 5833 reviewed Enzyme
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9HCG7 BXGT020533 Non-lysosomal glucosylceramidase 57704 reviewed
Q9Y3Z3 BXGT022268 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 25939 reviewed
Q9Y619 BXGT022316 Mitochondrial ornithine transporter 1 10166 reviewed Transporter
Q9UBP0 BXGT023601 Spastin 6683 reviewed Cellular structure
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
Q9Y4W6 BXGT025025 AFG3-like protein 2 10939 reviewed Enzyme
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
P09471 BXGT026153 Guanine nucleotide-binding protein G(o) subunit alpha 2775 reviewed Enzyme modulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease