adisease

Showing entry for Thyroid Nodule

General Disease Information
BXGD Id	BXGD002846
Disease Name	Thyroid Nodule
Disease CUI Id	C0040137
MeSH Codes	C04 C19
Disease Class Name	Neoplasms; Endocrine System Diseases
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id	HP:0000818
Human Phenotype Ontology Term	Abnormality of the endocrine system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15392	BXGT004162	Baculoviral IAP repeat-containing protein 5	332	reviewed	Enzyme modulator
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00740	BXGT005634	Coagulation factor IX	2158	reviewed	Enzyme
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P04278	BXGT006182	Sex hormone-binding globulin	6462	reviewed
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04629	BXGT006239	High affinity nerve growth factor receptor	4914	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04731	BXGT006251	Metallothionein-1A	4489	reviewed
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05187	BXGT006339	Alkaline phosphatase, placental type	250	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06731	BXGT006488	Carcinoembryonic antigen-related cell adhesion molecule 5	1048	reviewed
P06753	BXGT006498	Tropomyosin alpha-3 chain	7170	reviewed	Cellular structure
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08887	BXGT006835	Interleukin-6 receptor subunit alpha	3570	reviewed	Signaling
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09923	BXGT006942	Intestinal-type alkaline phosphatase	248	reviewed	Enzyme
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10323	BXGT007557	Acrosin	49	reviewed	Enzyme
P10646	BXGT007598	Tissue factor pathway inhibitor	7035	reviewed	Enzyme modulator
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P10909	BXGT007630	Clusterin	1191	reviewed
P10997	BXGT007643	Islet amyloid polypeptide	3375	reviewed	Signaling
P13489	BXGT007913	Ribonuclease inhibitor	6050	reviewed	Transcription factor
P13497	BXGT007915	Bone morphogenetic protein 1	649	reviewed
P14921	BXGT008068	Protein C-ets-1	2113	reviewed	Transcription factor
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16473	BXGT008234	Thyrotropin receptor	7253	reviewed	G-protein coupled receptor
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P17936	BXGT008357	Insulin-like growth factor-binding protein 3	3486	reviewed	Enzyme modulator
P18089	BXGT008379	Alpha-2B adrenergic receptor	151	reviewed	G-protein coupled receptor
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P25098	BXGT009015	Beta-adrenergic receptor kinase 1	156	reviewed	Kinase
P25101	BXGT009018	Endothelin-1 receptor	1909	reviewed	G-protein coupled receptor
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P28908	BXGT009302	Tumor necrosis factor receptor superfamily member 8	943	reviewed
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P30874	BXGT009475	Somatostatin receptor type 2	6752	reviewed	G-protein coupled receptor
P31391	BXGT009535	Somatostatin receptor type 4	6754	reviewed	G-protein coupled receptor
P31947	BXGT009589	14-3-3 protein sigma	2810	reviewed	Chaperone
P35348	BXGT009814	Alpha-1A adrenergic receptor	148	reviewed	G-protein coupled receptor
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P41212	BXGT010235	Transcription factor ETV6	2120	reviewed	Transcription factor
P48051	BXGT010611	G protein-activated inward rectifier potassium channel 2	3763	reviewed	Ion channel
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P63098	BXGT011497	Calcineurin subunit B type 1	5534	reviewed
P78417	BXGT011843	Glutathione S-transferase omega-1	9446	reviewed
P80365	BXGT011895	Corticosteroid 11-beta-dehydrogenase isozyme 2	3291	reviewed	Enzyme
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q06710	BXGT012887	Paired box protein Pax-8	7849	reviewed
Q08722	BXGT013002	Leukocyte surface antigen CD47	961	reviewed
Q14527	BXGT013479	Helicase-like transcription factor	6596	reviewed
Q15274	BXGT013556	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	23475	reviewed
Q6ZQY3	BXGT016636	Acidic amino acid decarboxylase GADL1	339896	reviewed
Q96A70	BXGT019615	Antizyme inhibitor 2	113451	reviewed	Enzyme
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UM73	BXGT021773	ALK tyrosine kinase receptor	238	reviewed	Kinase
Q9UPY3	BXGT021802	Endoribonuclease Dicer	23405	reviewed	Enzyme
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q92911	BXGT022650	Sodium/iodide cotransporter	6528	reviewed	Transporter
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}