Showing entry for Intestinal-type alkaline phosphatase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006942
Protein NameIntestinal-type alkaline phosphatase
Uniport IdP09923
GeneALPI
Gene Id248
DomainAlk_phosphatase
Pfam PF00245  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00730 Thiamine metabolism
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00790 Folate biosynthesis
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0016311 dephosphorylation
Biological Process GO:0007586 digestion
Biological Process GO:0006654 phosphatidic acid biosynthetic process
molecular function GO:0004035 alkaline phosphatase activity
molecular function GO:0000287 magnesium ion binding
molecular function GO:0002020 protease binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0031225 anchored component of membrane
cellular component GO:0005576 extracellular region
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1483166 Synthesis of PA
R-HSA-1483206 Glycerophospholipid biosynthesis
R-HSA-1483257 Phospholipid metabolism
R-HSA-163125 Post-translational modification: synthesis of GPI-anchored proteins
R-HSA-392499 Metabolism of proteins
R-HSA-556833 Metabolism of lipids
R-HSA-597592 Post-translational protein modification
R-HSA-8935690 Digestion
R-HSA-8963743 Digestion and absorption
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001815 BXGD000078 Primary Myelofibrosis Hemic and Lymphatic Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0004509 BXGD000275 Azoospermia Male Urogenital Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008497 BXGD000549 Choriocarcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014553 BXGD000931 Absence Epilepsy Nervous System Diseases
C0016667 BXGD001072 Fragile X Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0017601 BXGD001125 Glaucoma Eye Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022336 BXGD001535 Creutzfeldt-Jakob disease Infections; Nervous System Diseases; Mental Disorders
C0023418 BXGD001642 leukemia Neoplasms
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026847 BXGD001940 Spinal Muscular Atrophy Nervous System Diseases
C0026987 BXGD001957 Myelofibrosis Pathological Conditions, Signs and Symptoms; Neoplasms; Hemic and Lymphatic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0032320 BXGD002350 Pneumoperitoneum Digestive System Diseases
C0035412 BXGD002548 Rhabdomyosarcoma Neoplasms
C0035585 BXGD002561 Rickettsia Infections Infections
C0040128 BXGD002844 Thyroid Diseases Endocrine System Diseases
C0040137 BXGD002846 Thyroid Nodule Neoplasms; Endocrine System Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0220611 BXGD004295 Childhood Rhabdomyosarcoma Neoplasms
C0220633 BXGD004303 Uveal melanoma Neoplasms; Eye Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0278519 BXGD006531 Recurrent Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0279550 BXGD006635 Adult Rhabdomyosarcoma Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0281361 BXGD006774 Adenocarcinoma of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0282577 BXGD006816 Congenital Disorders of Glycosylation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0600260 BXGD009701 Lung Diseases, Obstructive Respiratory Tract Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1561826 BXGD013364 Overweight and obesity
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1845076 BXGD014708 Lymphoproliferative Syndrome, X-Linked, 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C1862939 BXGD016144 AMYOTROPHIC LATERAL SCLEROSIS 1 Nutritional and Metabolic Diseases; Nervous System Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2242710 BXGD016997 Intra-Abdominal Hypertension Musculoskeletal Diseases; Cardiovascular Diseases
C2609129 BXGD017167 Autoimmune pancreatitis Digestive System Diseases; Immune System Diseases
C2931038 BXGD017944 Pancreatic carcinoma, familial Digestive System Diseases; Neoplasms; Endocrine System Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2987145 BXGD018247 Pancreatic Intraepithelial Neoplasia-3
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3658208 BXGD019252 Dysbiosis Pathological Conditions, Signs and Symptoms
C3714948 BXGD019440 PACHYONYCHIA CONGENITA 3
C3805278 BXGD019474 Extrahepatic Cholangiocarcinoma Neoplasms
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000099 3,4-Dihydroxyphenylacetic acid 168.15
BXGC0000204 Theophylline 180.16
BXGC0000392 Eriodictyol 288.26
BXGC0001623 L-Tryptophan 204.23
BXGC0001691 Questiomycin A 212.2
BXGC0001868 Catechin 290.27
BXGC0002061 Aloeemodin 270.24
BXGC0002690 alpha-Catechin 290.27
BXGC0003214 L-(-)-Phenylalanine 165.19
BXGC0003534 Mangiferol 422.34
BXGC0004322 xi-3-Hydroxy-5-phenylpentanoic acid O-beta-D-Glucopyranoside 356.37
BXGC0005982 Curcumin 368.38
BXGC0006306 Myricetin 318.24
BXGC0006367 Mangiferin 422.34
BXGC0008753 Isoquercitrin 464.38
BXGC0008962 Gancaonin U 380.48
BXGC0009194 Quercetin 3-glucuronide 478.36
BXGC0011390 Dihydroroseoside 388.45
BXGC0011421 3-Hydroxy-1-(4-hydroxyphenyl)-1-propanone 166.17
BXGC0013582 Curcumin 368.13
BXGC0017933 Sulfuretin 270.05
BXGC0024810 curcumin 368.13
BXGC0024813 Demethoxycurcumin 338.12
BXGC0028589 5,6,7,8-Tetrahydroxy-2-(4-Hydroxyphenyl)Chromen-4-One 302.04
BXGC0032575 Leucine 131.09
BXGC0037242 Homoarginine 188.13
BXGC0044285 Hematoxylin 302.08
BXGC0050877 (2R,3S)-2-(3,4-Dihydroxyphenyl)-3,4-Dihydro-2H-Chromene-3,5,7-Triol;Hydrate 290.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein