adisease

Showing entry for Wheezing

General Disease Information
BXGD Id	BXGD003032
Disease Name	Wheezing
Disease CUI Id	C0043144
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Sign or Symptom
Human Phenotype Ontology Id	HP:0002086
Human Phenotype Ontology Term	Abnormality of the respiratory system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O14920	BXGT004110	Inhibitor of nuclear factor kappa-B kinase subunit beta	3551	reviewed	Kinase
O15111	BXGT004126	Inhibitor of nuclear factor kappa-B kinase subunit alpha	1147	reviewed	Kinase
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02763	BXGT005951	Alpha-1-acid glycoprotein 1	5004	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P07099	BXGT006546	Epoxide hydrolase 1	2052	reviewed
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P08700	BXGT006816	Interleukin-3	3562	reviewed
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10153	BXGT007544	Non-secretory ribonuclease	6036	reviewed
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P12724	BXGT007837	Eosinophil cationic protein	6037	reviewed
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P14616	BXGT008026	Insulin receptor-related protein	3645	reviewed	Kinase
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P17252	BXGT008294	Protein kinase C alpha type	5578	reviewed	Kinase
P18054	BXGT008370	Arachidonate 12-lipoxygenase, 12S-type	239	reviewed	Enzyme
P19525	BXGT008492	Interferon-induced, double-stranded RNA-activated protein kinase	5610	reviewed	Kinase
P20930	BXGT008616	Filaggrin	2312	reviewed	Cellular structure
P21549	BXGT008661	Serine--pyruvate aminotransferase	189	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P25963	BXGT009080	NF-kappa-B inhibitor alpha	4792	reviewed
P28161	BXGT009234	Glutathione S-transferase Mu 2	2946	reviewed
P29400	BXGT009343	Collagen alpha-5(IV) chain	1287	reviewed
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P32245	BXGT009614	Melanocortin receptor 4	4160	reviewed	G-protein coupled receptor
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P37088	BXGT009961	Amiloride-sensitive sodium channel subunit alpha	6337	reviewed	Ion channel
P42226	BXGT010288	Signal transducer and activator of transcription 6	6778	reviewed	Nucleic acid binding
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P51168	BXGT010842	Amiloride-sensitive sodium channel subunit beta	6338	reviewed	Ion channel
P51170	BXGT010843	Amiloride-sensitive sodium channel subunit gamma	6340	reviewed	Ion channel
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	4088	reviewed	Transcription factor
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q8N608	BXGT018522	Inactive dipeptidyl peptidase 10	57628	reviewed	Enzyme
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q8TAX9	BXGT018788	Gasdermin-B	55876	reviewed
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q99581	BXGT019937	Protein FEV	54738	reviewed	Transcription factor
Q9BZ11	BXGT020193	Disintegrin and metalloproteinase domain-containing protein 33	80332	reviewed	Enzyme
Q9C0B1	BXGT020209	Alpha-ketoglutarate-dependent dioxygenase FTO	79068	reviewed
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
P20809	BXGT025043	Interleukin-11	3589	reviewed
Q6ZTQ4	BXGT025244	Cadherin-related family member 3	222256	reviewed
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor
P21731	BXGT026174	Thromboxane A2 receptor	6915	reviewed	G-protein coupled receptor

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}