Showing entry for Adult type dermatomyositis


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD004383
Disease NameAdult type dermatomyositis
Disease CUI IdC0221056
MeSH Codes C17   C05   C10  
Disease Class NameSkin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O15164 BXGT004133 Transcription intermediary factor 1-alpha 8805 reviewed
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O15553 BXGT004181 Pyrin 4210 reviewed
O75923 BXGT005166 Dysferlin 8291 reviewed Transporter
O95786 BXGT005396 Probable ATP-dependent RNA helicase DDX58 23586 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00492 BXGT005556 Hypoxanthine-guanine phosphoribosyltransferase 3251 reviewed Enzyme
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01574 BXGT005768 Interferon beta 3456 reviewed
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02144 BXGT005853 Myoglobin 4151 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02748 BXGT005940 Complement component C9 735 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03950 BXGT006116 Angiogenin 283 reviewed
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05161 BXGT006331 Ubiquitin-like protein ISG15 9636 reviewed Nucleic acid binding
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05413 BXGT006355 Fatty acid-binding protein, heart 2170 reviewed
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P06681 BXGT006468 Complement C2 717 reviewed
P07202 BXGT006565 Thyroid peroxidase 7173 reviewed Enzyme
P07711 BXGT006661 Cathepsin L1 1514 reviewed Enzyme
P08246 BXGT006756 Neutrophil elastase 1991 reviewed Enzyme
P08311 BXGT006762 Cathepsin G 1511 reviewed Enzyme
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P10144 BXGT007541 Granzyme B 3002 reviewed Enzyme
P10323 BXGT007557 Acrosin 49 reviewed Enzyme
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P10809 BXGT007617 60 kDa heat shock protein, mitochondrial 3329 reviewed
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P12273 BXGT007787 Prolactin-inducible protein 5304 reviewed
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14618 BXGT008027 Pyruvate kinase PKM 5315 reviewed Kinase
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15169 BXGT008093 Carboxypeptidase N catalytic chain 1369 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15941 BXGT008176 Mucin-1 4582 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P20591 BXGT008586 Interferon-induced GTP-binding protein Mx1 4599 reviewed Enzyme modulator
P21860 BXGT008698 Receptor tyrosine-protein kinase erbB-3 2065 reviewed Kinase
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P22894 BXGT008815 Neutrophil collagenase 4317 reviewed Enzyme
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P23219 BXGT008837 Prostaglandin G/H synthase 1 5742 reviewed Enzyme
P23246 BXGT008840 Splicing factor, proline- and glutamine-rich 6421 reviewed Nucleic acid binding
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P29597 BXGT009367 Non-receptor tyrosine-protein kinase TYK2 7297 reviewed Kinase
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P40189 BXGT010164 Interleukin-6 receptor subunit beta 3572 reviewed Signaling
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P40933 BXGT010209 Interleukin-15 3600 reviewed
P41182 BXGT010231 B-cell lymphoma 6 protein 604 reviewed
P41250 BXGT010244 Glycine--tRNA ligase 2617 reviewed Enzyme
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P49913 BXGT010761 Cathelicidin antimicrobial peptide 820 reviewed
P51451 BXGT010848 Tyrosine-protein kinase Blk 640 reviewed Kinase
P51692 BXGT010885 Signal transducer and activator of transcription 5B 6777 reviewed Nucleic acid binding
P55212 BXGT011112 Caspase-6 839 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P78536 BXGT011847 Disintegrin and metalloproteinase domain-containing protein 17 6868 reviewed
Q13144 BXGT013317 Translation initiation factor eIF-2B subunit epsilon 8893 reviewed
Q13231 BXGT013329 Chitotriosidase-1 1118 reviewed
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14118 BXGT013444 Dystroglycan 1605 reviewed Receptor
Q14149 BXGT013449 MORC family CW-type zinc finger protein 3 23515 reviewed
Q15046 BXGT013527 Lysine--tRNA ligase 3735 reviewed Enzyme
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q16658 BXGT013651 Fascin 6624 reviewed Cellular structure
Q16853 BXGT013683 Membrane primary amine oxidase 8639 reviewed
Q86WV6 BXGT017626 Stimulator of interferon genes protein 340061 reviewed
Q8WTT0 BXGT018987 C-type lectin domain family 4 member C 170482 reviewed Receptor
Q8WZ42 BXGT019023 Titin 7273 reviewed Kinase
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9HBE5 BXGT020518 Interleukin-21 receptor 50615 reviewed Receptor
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NYK1 BXGT021258 Toll-like receptor 7 51284 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UBB5 BXGT021649 Methyl-CpG-binding domain protein 2 8932 reviewed Epigenetic regulator
Q9UHX1 BXGT021707 Poly(U)-binding-splicing factor PUF60 22827 reviewed
Q9UJ71 BXGT021725 C-type lectin domain family 4 member K 50489 reviewed Receptor
Q9UKV8 BXGT021752 Protein argonaute-2 27161 reviewed
Q9UPN9 BXGT021799 E3 ubiquitin-protein ligase TRIM33 51592 reviewed
Q9Y275 BXGT022223 Tumor necrosis factor ligand superfamily member 13B 10673 reviewed
Q9Y2R2 BXGT022243 Tyrosine-protein phosphatase non-receptor type 22 26191 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q5JP69 BXGT022691 C3/C5 convertase 717 unreviewed
Q96C86 BXGT022803 m7GpppX diphosphatase 28960 reviewed Enzyme
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q63ZY3 BXGT023544 KN motif and ankyrin repeat domain-containing protein 2 25959 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
Q96MS0 BXGT025241 Roundabout homolog 3 64221 reviewed Receptor
P19474 BXGT025520 E3 ubiquitin-protein ligase TRIM21 6737 reviewed
Q9UKU9 BXGT025985 Angiopoietin-related protein 2 23452 reviewed Signaling
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease