Showing entry for Membrane primary amine oxidase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013683
Protein NameMembrane primary amine oxidase
Uniport IdQ16853
GeneAOC3
Gene Id8639
DomainCu_amine_oxid; Cu_amine_oxidN2; Cu_amine_oxidN3
Pfam PF01179   PF02727   PF02728  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.5 Amino acid metabolism hsa00260 Glycine, serine and threonine metabolism
1. Metabolism 1.5 Amino acid metabolism hsa00350 Tyrosine metabolism
1. Metabolism 1.5 Amino acid metabolism hsa00360 Phenylalanine metabolism
1. Metabolism 1.6 Metabolism of other amino acids hsa00410 beta-Alanine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009308 amine metabolic process
Biological Process GO:0007155 cell adhesion
Biological Process GO:0006954 inflammatory response
Biological Process GO:1902283 negative regulation of primary amine oxidase activity
Biological Process GO:0046677 response to antibiotic
Biological Process GO:0006805 xenobiotic metabolic process
molecular function GO:0052595 aliphatic-amine oxidase activity
molecular function GO:0052594 aminoacetone:oxygen oxidoreductase(deaminating) activity
molecular function GO:0005509 calcium ion binding
molecular function GO:0005507 copper ion binding
molecular function GO:0042802 identical protein binding
molecular function GO:0052596 phenethylamine:oxygen oxidoreductase (deaminating) activity
molecular function GO:0008131 primary amine oxidase activity
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0048038 quinone binding
molecular function GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity
cellular component GO:0009986 cell surface
cellular component GO:0005737 cytoplasm
cellular component GO:0005769 early endosome
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005794 Golgi apparatus
cellular component GO:0016021 integral component of membrane
cellular component GO:0005902 microvillus
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-211859 Biological oxidations
R-HSA-211945 Phase I - Functionalization of compounds
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001363 BXGD000046 Acute vascular insufficiency of intestine (disorder) Digestive System Diseases
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002152 BXGD000104 Alloxan Diabetes Nutritional and Metabolic Diseases; Endocrine System Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003486 BXGD000197 Aortic Aneurysm Cardiovascular Diseases
C0003493 BXGD000199 Aortic Diseases Cardiovascular Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007766 BXGD000478 Intracranial Aneurysm Nervous System Diseases; Cardiovascular Diseases
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009763 BXGD000628 Conjunctivitis Eye Diseases
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011633 BXGD000742 Dermatomyositis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011875 BXGD000757 Diabetic Angiopathies Endocrine System Diseases; Cardiovascular Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0014038 BXGD000878 Encephalitis Nervous System Diseases
C0014060 BXGD000882 Encephalitis, St. Louis Infections; Nervous System Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0017667 BXGD001142 Nodular glomerulosclerosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024198 BXGD001743 Lyme Disease Infections
C0025202 BXGD001832 melanoma Neoplasms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030524 BXGD002236 Paratuberculosis Infections; Animal Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0036429 BXGD002614 Sclerosis Pathological Conditions, Signs and Symptoms
C0038433 BXGD002754 Streptozotocin Diabetes Nutritional and Metabolic Diseases; Endocrine System Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0041948 BXGD002939 Uremia Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042164 BXGD002965 Uveitis Eye Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085220 BXGD003142 Cerebral Amyloid Angiopathy Nutritional and Metabolic Diseases; Nervous System Diseases; Cardiovascular Diseases
C0154830 BXGD003746 Proliferative diabetic retinopathy Pathological Conditions, Signs and Symptoms; Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0221056 BXGD004383 Adult type dermatomyositis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0238190 BXGD004890 Inclusion Body Myositis (disorder) Musculoskeletal Diseases; Nervous System Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0265004 BXGD005446 Dilatation of aorta Cardiovascular Diseases
C0265010 BXGD005448 Ruptured thoracic aortic aneurysm Respiratory Tract Diseases; Cardiovascular Diseases; Wounds and Injuries
C0265012 BXGD005449 Ruptured abdominal aortic aneurysm Cardiovascular Diseases; Wounds and Injuries
C0342257 BXGD007447 Complications of Diabetes Mellitus Endocrine System Diseases
C0398680 BXGD008214 Sarcoid myopathy Musculoskeletal Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0403447 BXGD008285 Chronic Kidney Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0409959 BXGD008400 Osteoarthritis, Knee Musculoskeletal Diseases
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0524910 BXGD009248 Hepatitis C, Chronic Digestive System Diseases; Infections
C0566602 BXGD009489 Primary sclerosing cholangitis Digestive System Diseases
C0600518 BXGD009711 Choroidal Neovascularization Pathological Conditions, Signs and Symptoms; Eye Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0741160 BXGD010025 Aortic Aneurysm, Ruptured Cardiovascular Diseases; Wounds and Injuries
C0742468 BXGD010063 Central nervous system lesion
C0746102 BXGD010136 Chronic lung disease Respiratory Tract Diseases
C0856169 BXGD011096 Endothelial dysfunction
C1176475 BXGD011798 Ductal Carcinoma Neoplasms
C1262091 BXGD011867 Lymphocytic infiltration
C1269955 BXGD012005 Tumor Cell Invasion
C1305122 BXGD012344 Thoracoabdominal aortic aneurysm, ruptured Cardiovascular Diseases; Wounds and Injuries
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1333177 BXGD012605 Lymphoproliferative Disorder of the Skin Skin and Connective Tissue Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C1527349 BXGD013277 Ductal Breast Carcinoma Neoplasms
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1832370 BXGD013832 MYOPATHY, MYOFIBRILLAR, DESMIN-RELATED Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Cardiovascular Diseases
C1842937 BXGD014546 AURAL ATRESIA, CONGENITAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1845050 BXGD014703 PIGMENTARY DISORDER, RETICULATE, WITH SYSTEMIC MANIFESTATIONS Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C3642346 BXGD019245 Luminal B Breast Carcinoma
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C4020969 BXGD020517 Inflammatory abnormality of the eye
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002390 Spermine 202.34
BXGC0002586 Calcium 40.08
BXGC0003705 Chloride 35.45
BXGC0004760 2-Phenylethylamine 121.18
BXGC0005794 Benzylamine 107.15
BXGC0005871 Dopamine 153.18
BXGC0006368 Formic acid 46.03
BXGC0018397 beta-1,4-mannan 180.06
BXGC0042188 1H-Benzimidazol-2-Amine 133.06
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein