Showing entry for Angiogenin


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006116
Protein NameAngiogenin
Uniport IdP03950
GeneANG
Gene Id283
DomainRnaseA
Pfam PF00074  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030041 actin filament polymerization
Biological Process GO:0032431 activation of phospholipase A2 activity
Biological Process GO:0007202 activation of phospholipase C activity
Biological Process GO:0032148 activation of protein kinase B activity
Biological Process GO:0034332 adherens junction organization
Biological Process GO:0001525 angiogenesis
Biological Process GO:0019731 antibacterial humoral response
Biological Process GO:0019732 antifungal humoral response
Biological Process GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
Biological Process GO:0007154 cell communication
Biological Process GO:0016477 cell migration
Biological Process GO:0050830 defense response to Gram-positive bacterium
Biological Process GO:0006651 diacylglycerol biosynthetic process
Biological Process GO:0042592 homeostatic process
Biological Process GO:0045087 innate immune response
Biological Process GO:0048662 negative regulation of smooth muscle cell proliferation
Biological Process GO:0017148 negative regulation of translation
Biological Process GO:0001556 oocyte maturation
Biological Process GO:0001541 ovarian follicle development
Biological Process GO:0001890 placenta development
Biological Process GO:0001938 positive regulation of endothelial cell proliferation
Biological Process GO:0042327 positive regulation of phosphorylation
Biological Process GO:0050714 positive regulation of protein secretion
Biological Process GO:0009725 response to hormone
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0001878 response to yeast
Biological Process GO:0009303 rRNA transcription
molecular function GO:0003779 actin binding
molecular function GO:0005507 copper ion binding
molecular function GO:0003677 DNA binding
molecular function GO:0004519 endonuclease activity
molecular function GO:0008201 heparin binding
molecular function GO:0042277 peptide binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0004540 ribonuclease activity
molecular function GO:0019843 rRNA binding
molecular function GO:0005102 signaling receptor binding
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0032311 angiogenin-PRI complex
cellular component GO:0005604 basement membrane
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0030426 growth cone
cellular component GO:0043025 neuronal cell body
cellular component GO:0005730 nucleolus
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1500931 Cell-Cell communication
R-HSA-418990 Adherens junctions interactions
R-HSA-421270 Cell-cell junction organization
R-HSA-446728 Cell junction organization
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001349 BXGD000044 Acute-Phase Reaction Pathological Conditions, Signs and Symptoms
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007140 BXGD000447 Carcinosarcoma Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0008497 BXGD000549 Choriocarcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0010093 BXGD000652 Corpus Luteum Cyst Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011633 BXGD000742 Dermatomyositis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0013404 BXGD000833 Dyspnea Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0016057 BXGD001042 Fibrosarcoma Neoplasms
C0016667 BXGD001072 Fragile X Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0017921 BXGD001152 Glycogen storage disease type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018915 BXGD001244 Hemangioendothelioma Neoplasms
C0018916 BXGD001245 Hemangioma Neoplasms
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0023066 BXGD001605 Laryngospasm Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024282 BXGD001755 Lymphocytosis Hemic and Lymphatic Diseases
C0024305 BXGD001763 Lymphoma, Non-Hodgkin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0026847 BXGD001940 Spinal Muscular Atrophy Nervous System Diseases
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027430 BXGD001988 Nasal Polyps Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0027498 BXGD001994 Nausea and vomiting Pathological Conditions, Signs and Symptoms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027746 BXGD002032 Nerve Degeneration Pathological Conditions, Signs and Symptoms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029927 BXGD002182 Ovarian Cysts Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0033246 BXGD002401 Proctitis Digestive System Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0033999 BXGD002448 Pterygium Eye Diseases
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0035344 BXGD002541 Retinopathy of Prematurity Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0035585 BXGD002561 Rickettsia Infections Infections
C0037763 BXGD002699 Spasm Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0043352 BXGD003045 Xerostomia Stomatognathic Diseases
C0079773 BXGD003100 Lymphoma, T-Cell, Cutaneous Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085084 BXGD003121 Motor Neuron Disease Nervous System Diseases
C0085215 BXGD003141 Ovarian Failure, Premature Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085631 BXGD003214 Agitation Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0085633 BXGD003216 Mood swings Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0149521 BXGD003328 Pancreatitis, Chronic Digestive System Diseases
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0149896 BXGD003382 Primary gout Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0153633 BXGD003674 Malignant neoplasm of brain Neoplasms; Nervous System Diseases
C0154682 BXGD003731 Lateral Sclerosis Nervous System Diseases
C0154830 BXGD003746 Proliferative diabetic retinopathy Pathological Conditions, Signs and Symptoms; Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206657 BXGD004220 Alveolar Soft Part Sarcoma Neoplasms
C0206733 BXGD004278 Strawberry nevus of skin Neoplasms
C0220605 BXGD004294 Adult Non-Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220612 BXGD004296 Childhood Non-Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221056 BXGD004383 Adult type dermatomyositis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238461 BXGD004936 Anaplastic thyroid carcinoma Neoplasms
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0242422 BXGD005163 Parkinsonian Disorders Nervous System Diseases
C0263630 BXGD005335 Hypertrophic disorder of skin, unspecified Skin and Connective Tissue Diseases
C0265950 BXGD005588 Venous malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0271066 BXGD006156 Choroidal retinal neovascularization Pathological Conditions, Signs and Symptoms; Eye Diseases
C0278595 BXGD006545 Adult Fibrosarcoma Neoplasms
C0278701 BXGD006566 Gastric Adenocarcinoma Digestive System Diseases; Neoplasms
C0278877 BXGD006608 Adult Meningioma Neoplasms; Nervous System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0282612 BXGD006820 Prostatic Intraepithelial Neoplasias Neoplasms
C0338106 BXGD007167 Adenocarcinoma of colon Digestive System Diseases; Neoplasms
C0341472 BXGD007411 Obstructive chronic pancreatitis Digestive System Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0427065 BXGD008604 Distal muscle weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0522224 BXGD009198 Paralysed Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0541794 BXGD009262 Skeletal muscle atrophy
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0683381 BXGD009787 inflammatory joint disease
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0740391 BXGD009987 Middle Cerebral Artery Occlusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0746674 BXGD010147 Generalized muscle weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0795842 BXGD010747 chromosome 11q duplication syndrome Pathological Conditions, Signs and Symptoms
C0856169 BXGD011096 Endothelial dysfunction
C1145670 BXGD011764 Respiratory Failure Respiratory Tract Diseases
C1260959 BXGD011846 Drusen
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1275303 BXGD012079 Erythrodermic mycosis fungoides Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1282209 BXGD012138 Choroidal neovascular membrane (disorder)
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1456868 BXGD013128 Diabetic foot ulcer Skin and Connective Tissue Diseases; Endocrine System Diseases; Cardiovascular Diseases
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1611743 BXGD013456 Familial (FPAH)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1762616 BXGD013753 Meningioma, benign, no ICD-O subtype Neoplasms; Nervous System Diseases
C1848736 BXGD014970 Distal amyotrophy
C1862939 BXGD016144 AMYOTROPHIC LATERAL SCLEROSIS 1 Nutritional and Metabolic Diseases; Nervous System Diseases
C1862941 BXGD016145 Amyotrophic Lateral Sclerosis, Sporadic Nutritional and Metabolic Diseases; Nervous System Diseases
C1867441 BXGD016455 Pterygium Of Conjunctiva And Cornea Eye Diseases
C1868683 BXGD016526 B-CELL MALIGNANCY, LOW-GRADE
C1963060 BXGD016679 Agitation, CTCAE 3.0
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2316786 BXGD017028 Chronic kidney disease stage 2 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2678468 BXGD017411 Amyotrophic Lateral Sclerosis 9 Nutritional and Metabolic Diseases; Nervous System Diseases
C2937220 BXGD018154 Congenital abnormality of vein Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2960127 BXGD018197 Heart failure with normal ejection fraction Cardiovascular Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3275069 BXGD018658 Chronic Total Occlusion Vessel
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3695127 BXGD019344 Astrocytoma of brain Neoplasms; Nervous System Diseases
C3714534 BXGD019411 dowling-degos disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C3714948 BXGD019440 PACHYONYCHIA CONGENITA 3
C3828464 BXGD019741 Proneural Glioblastoma
C4022587 BXGD020928 Fatigable weakness of respiratory muscles
C4022588 BXGD020929 Fatigable weakness of swallowing muscles
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4317089 BXGD022721 Infantile hemangioma Neoplasms; Cardiovascular Diseases
C4509226 BXGD022972 Heart failure with preserved ejection fraction [HFpEF]
C4520843 BXGD023043 Pterygium of eye Eye Diseases
C4552811 BXGD023526 Generalized Muscle Weakness, CTCAE
C4552855 BXGD023528 Agitation, CTCAE 5.0
C4553743 BXGD023548 Spasticity, CTCAE
C4721532 BXGD023752 Lymphoma, Non-Hodgkin, Familial Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000076 p-Coumaroyl tartaric acid glucosidic ester 150.09
BXGC0000436 Glycerol 92.09
BXGC0000696 Tartaric acid 150.09
BXGC0000989 Glutathione 307.32
BXGC0003705 Chloride 35.45
BXGC0006198 Citric acid 192.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein