adisease

Showing entry for Multiple tumors

General Disease Information
BXGD Id	BXGD005227
Disease Name	Multiple tumors
Disease CUI Id	C0260037
MeSH Codes	C04
Disease Class Name	Neoplasms
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O15151	BXGT004132	Protein Mdm4	4194	reviewed	Nucleic acid binding
O95255	BXGT005363	Multidrug resistance-associated protein 6	368	reviewed	Transporter
O95257	BXGT005365	Growth arrest and DNA damage-inducible protein GADD45 gamma	10912	reviewed
P00505	BXGT005560	Aspartate aminotransferase, mitochondrial	2806	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00740	BXGT005634	Coagulation factor IX	2158	reviewed	Enzyme
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P07203	BXGT006566	Glutathione peroxidase 1	2876	reviewed	Enzyme
P07355	BXGT006609	Annexin A2	302	reviewed
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P11308	BXGT007684	Transcriptional regulator ERG	2078	reviewed	Transcription factor
P11309	BXGT007685	Serine/threonine-protein kinase pim-1	5292	reviewed	Kinase
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P11802	BXGT007750	Cyclin-dependent kinase 4	1019	reviewed	Kinase
P12830	BXGT007852	Cadherin-1	999	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14207	BXGT007993	Folate receptor beta	2350	reviewed
P14625	BXGT008029	Endoplasmin	7184	reviewed	Chaperone
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15328	BXGT008108	Folate receptor alpha	2348	reviewed
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P19544	BXGT008494	Wilms tumor protein	7490	reviewed	Nucleic acid binding
P20340	BXGT008566	Ras-related protein Rab-6A	5870	reviewed
P21359	BXGT008640	Neurofibromin	4763	reviewed	Enzyme modulator
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P27635	BXGT009194	60S ribosomal protein L10	6134	reviewed	Nucleic acid binding
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P33176	BXGT009699	Kinesin-1 heavy chain	3799	reviewed	Cellular structure
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35414	BXGT009829	Apelin receptor	187	reviewed	G-protein coupled receptor
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P46527	BXGT010525	Cyclin-dependent kinase inhibitor 1B	1027	reviewed
P46937	BXGT010554	Transcriptional coactivator YAP1	10413	reviewed	Enzyme modulator
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P49789	BXGT010742	Bis(5'-adenosyl)-triphosphatase	2272	reviewed
P50281	BXGT010788	Matrix metalloproteinase-14	4323	reviewed	Enzyme
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
Q13309	BXGT013338	S-phase kinase-associated protein 2	6502	reviewed
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q14790	BXGT013505	Caspase-8	841	reviewed	Enzyme
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q53EZ4	BXGT015010	Centrosomal protein of 55 kDa	55165	reviewed
Q86Z14	BXGT017639	Beta-klotho	152831	reviewed	Enzyme
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UBB5	BXGT021649	Methyl-CpG-binding domain protein 2	8932	reviewed	Epigenetic regulator
Q9UNL4	BXGT021790	Inhibitor of growth protein 4	51147	reviewed	Nucleic acid binding
Q9UPY3	BXGT021802	Endoribonuclease Dicer	23405	reviewed	Enzyme
P35240	BXGT022927	Merlin	4771	reviewed
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
P19875	BXGT023294	C-X-C motif chemokine 2	2920	reviewed	Signaling
Q16254	BXGT023368	Transcription factor E2F4	1874	reviewed	Nucleic acid binding
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}