Showing entry for Primary Progressive Aphasia (disorder)


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD006808
Disease NamePrimary Progressive Aphasia (disorder)
Disease CUI IdC0282513
MeSH Codes C23   C10   F03  
Disease Class NamePathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
Semantic TypeMental or Behavioral Dysfunction
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630   DOID:7   DOID:150  
Disease Ontology Class Namegenetic disease; disease of anatomical entity; disease of mental health
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O14763 BXGT004093 Tumor necrosis factor receptor superfamily member 10B 8795 reviewed
O15409 BXGT004166 Forkhead box protein P2 93986 reviewed
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02654 BXGT005911 Apolipoprotein C-I 341 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04156 BXGT006156 Major prion protein 5621 reviewed
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P14784 BXGT008054 Interleukin-2 receptor subunit beta 3560 reviewed Receptor
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P29074 BXGT009313 Tyrosine-protein phosphatase non-receptor type 4 5775 reviewed
P35858 BXGT009876 Insulin-like growth factor-binding protein complex acid labile subunit 3483 reviewed Receptor
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P52758 BXGT010951 2-iminobutanoate/2-iminopropanoate deaminase 10247 reviewed
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P78330 BXGT011833 Phosphoserine phosphatase 5723 reviewed Enzyme
P80404 BXGT011907 4-aminobutyrate aminotransferase, mitochondrial 18 reviewed Enzyme
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q92945 BXGT019397 Far upstream element-binding protein 2 8570 reviewed Enzyme
Q9BXH1 BXGT020167 Bcl-2-binding component 3 27113 reviewed
Q9Y286 BXGT022225 Sialic acid-binding Ig-like lectin 7 27036 reviewed Receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease