Showing entry for Forkhead box protein P2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004166
Protein NameForkhead box protein P2
Uniport IdO15409
GeneFOXP2
Gene Id93986
DomainForkhead; FOXP-CC
Pfam PF00250   PF16159  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0043010 camera-type eye development
Biological Process GO:0021757 caudate nucleus development
Biological Process GO:0021549 cerebellum development
Biological Process GO:0021987 cerebral cortex development
Biological Process GO:0098582 innate vocalization behavior
Biological Process GO:0048286 lung alveolus development
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis
Biological Process GO:0002053 positive regulation of mesenchymal cell proliferation
Biological Process GO:0009791 post-embryonic development
Biological Process GO:0021758 putamen development
Biological Process GO:0033574 response to testosterone
Biological Process GO:0060013 righting reflex
Biological Process GO:0007519 skeletal muscle tissue development
Biological Process GO:0048745 smooth muscle tissue development
Biological Process GO:0042297 vocal learning
molecular function GO:0050681 androgen receptor binding
molecular function GO:0003677 DNA binding
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
molecular function GO:0042802 identical protein binding
molecular function GO:0046872 metal ion binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0043565 sequence-specific DNA binding
cellular component GO:0000790 nuclear chromatin
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0003635 BXGD000214 Apraxias Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005890 BXGD000345 Body Height
C0006111 BXGD000369 Brain Diseases Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008060 BXGD000516 child abuse behavior
C0008073 BXGD000518 Developmental Disabilities Mental Disorders
C0008354 BXGD000533 Cholera Infections
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009460 BXGD000615 Communication impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010606 BXGD000677 Adenoid Cystic Carcinoma Neoplasms
C0011269 BXGD000710 Dementia, Vascular Nervous System Diseases; Mental Disorders; Cardiovascular Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013132 BXGD000799 Drooling Stomatognathic Diseases
C0013362 BXGD000817 Dysarthria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0017168 BXGD001101 Gastroesophageal reflux disease Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017658 BXGD001138 Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0018524 BXGD001200 Hallucinations Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020625 BXGD001451 Hyponatremia Nutritional and Metabolic Diseases
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0021831 BXGD001516 Intestinal Diseases Digestive System Diseases
C0023009 BXGD001598 Speech and language disorder Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0023012 BXGD001599 Language Delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0023014 BXGD001600 Language Development Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0023015 BXGD001601 Language Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0025362 BXGD001866 Mental Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026470 BXGD001903 Monoclonal Gammopathy of Undetermined Significance Immune System Diseases; Hemic and Lymphatic Diseases
C0026650 BXGD001913 Movement Disorders Nervous System Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027404 BXGD001984 Narcolepsy Nervous System Diseases; Mental Disorders
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0036337 BXGD002598 Schizoaffective Disorder Mental Disorders
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036363 BXGD002607 Schizotypal Personality Disorder Mental Disorders
C0037822 BXGD002706 Speech Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038506 BXGD002766 Stuttering Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038868 BXGD002781 Progressive supranuclear palsy Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0153452 BXGD003647 Malignant neoplasm of gallbladder Digestive System Diseases; Neoplasms
C0175693 BXGD004001 Russell-Silver syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0221765 BXGD004477 Chronic schizophrenia Mental Disorders
C0232466 BXGD004543 Feeding difficulties
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233762 BXGD004610 Hallucinations, Auditory Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0234526 BXGD004684 Ideational Apraxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0234527 BXGD004685 Apraxia, Motor Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0234529 BXGD004686 Dressing Apraxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0236642 BXGD004815 Pick Disease of the Brain Nervous System Diseases; Mental Disorders
C0236818 BXGD004839 Selective Mutism Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0241210 BXGD005086 Speech Delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0264611 BXGD005403 Apraxia of Phonation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0282513 BXGD006808 Primary Progressive Aphasia (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0349231 BXGD007896 Phobic anxiety disorder Mental Disorders
C0349391 BXGD007900 Apraxia, Verbal Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376634 BXGD008006 Craniofacial Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0422892 BXGD008463 Apraxia, Gestural Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0424574 BXGD008534 Duration of sleep
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0432103 BXGD008722 Submucous cleft of hard palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0454595 BXGD008841 Motor speech disorder
C0454608 BXGD008847 Apraxia, Oral Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0454641 BXGD008848 Expressive language delay
C0454642 BXGD008849 Receptive language delay
C0454644 BXGD008850 Delayed speech and language development Behavior and Behavior Mechanisms
C0454651 BXGD008851 Specific language impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0454655 BXGD008852 Semantic-Pragmatic Disorder Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0476254 BXGD008984 Dyslexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0494423 BXGD009028 Specific developmental disorders of speech and language
C0524528 BXGD009229 Pervasive Development Disorder Mental Disorders
C0556280 BXGD009440 Gross motor impairment
C0557874 BXGD009444 Global developmental delay
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0596887 BXGD009648 mathematical ability
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0730557 BXGD009965 Emotional abuse
C0750927 BXGD010254 Apraxia, Developmental Verbal Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0750928 BXGD010255 Apraxia, Facial-Oral Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0751050 BXGD010305 Communication Disorders, Developmental Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0751072 BXGD010312 Frontotemporal Lobar Degeneration Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0751257 BXGD010367 Auditory Processing Disorder, Central Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751265 BXGD010370 Learning Disabilities Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0751633 BXGD010529 Carotid Artery Plaque Nervous System Diseases; Cardiovascular Diseases
C0852418 BXGD010944 Speech and language abnormalities
C0856975 BXGD011127 Autistic behavior Behavior and Behavior Mechanisms
C0871215 BXGD011313 Reading Disabilities
C0871470 BXGD011316 Systolic Pressure
C0920296 BXGD011464 Developmental reading disorder Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0949664 BXGD011583 Tauopathies Nervous System Diseases
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306620 BXGD012371 Systolic blood pressure measurement
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1456326 BXGD013114 Selective mutism specific to childhood and adolescence
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1611743 BXGD013456 Familial (FPAH)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1737329 BXGD013728 Dysmorphism Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1837404 BXGD014229 High, narrow palate
C1837731 BXGD014260 Overfolded helix
C1838027 BXGD014290 Incomprehensible speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1845668 BXGD014757 Perisylvian syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C1848207 BXGD014916 Poor speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1858116 BXGD015773 Caudate atrophy
C1867864 BXGD016472 Poor fine motor coordination
C2004345 BXGD016870 phonological developmental disorder Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2721589 BXGD017539 Verbal hallucinations
C3160814 BXGD018477 Cannabis use
C3277019 BXGD018698 Horizontal eyebrow
C3495144 BXGD018979 Apraxia, Articulatory Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3811918 BXGD019664 GRN-related frontotemporal dementia Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C4019167 BXGD020466 Speech Sound Disorders Mental Disorders
C4021845 BXGD020816 Oromotor apraxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C4022906 BXGD021033 Delayed social development
C4024956 BXGD021499 Grammar-specific speech disorder Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4025790 BXGD021791 Specific learning disability
C4025871 BXGD021839 Abnormality of the face
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4520981 BXGD023051 Abnormality of the basal ganglia
C4531122 BXGD023190 Abnormal speech prosody
C4750783 BXGD024072 7q31 microdeletion syndrome
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein