Showing entry for Tyrosine-protein phosphatase non-receptor type 5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011085
Protein NameTyrosine-protein phosphatase non-receptor type 5
Uniport IdP54829
GenePTPN5
Gene Id84867
DomainY_phosphatase
Pfam PF00102  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071345 cellular response to cytokine stimulus
Biological Process GO:0006470 protein dephosphorylation
molecular function GO:0001784 phosphotyrosine residue binding
molecular function GO:0004725 protein tyrosine phosphatase activity
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-168256 Immune System
R-HSA-446652 Interleukin-1 family signaling
R-HSA-449147 Signaling by Interleukins
R-HSA-9008059 Interleukin-37 signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002622 BXGD000119 Amnesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007787 BXGD000487 Transient Ischemic Attack Nervous System Diseases; Cardiovascular Diseases
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0016667 BXGD001072 Fragile X Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0026650 BXGD001913 Movement Disorders Nervous System Diseases
C0027092 BXGD001971 Myopia Eye Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027746 BXGD002032 Nerve Degeneration Pathological Conditions, Signs and Symptoms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036992 BXGD002654 Short Bowel Syndrome Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0162810 BXGD003982 Cicatrix, Hypertrophic Pathological Conditions, Signs and Symptoms
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0234251 BXGD004645 Inflammatory pain Pathological Conditions, Signs and Symptoms
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0338908 BXGD007218 Mixed anxiety and depressive disorder Mental Disorders
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0393642 BXGD008111 Sepsis-Associated Encephalopathy Nervous System Diseases
C0409959 BXGD008400 Osteoarthritis, Knee Musculoskeletal Diseases
C0423673 BXGD008495 Pain in spine Pathological Conditions, Signs and Symptoms
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0598935 BXGD009674 Tumor Initiation Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0678356 BXGD009755 alcohol effect
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0751295 BXGD010383 Memory Loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0752308 BXGD010715 Hypoxia-Ischemia, Brain Nervous System Diseases; Cardiovascular Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1854310 BXGD015392 Hypotrichosis simplex Skin and Connective Tissue Diseases
C2363741 BXGD017100 HIV-1 infection
C2936719 BXGD018130 Mechanical Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0042336 7-Amino-4-Hydroxynaphthalene-2-Sulfonic Acid 239.03
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein