Showing entry for Cutaneous Mastocytosis


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD011703
Disease NameCutaneous Mastocytosis
Disease CUI IdC1136033
MeSH Codes C04   C17  
Disease Class NameNeoplasms; Skin and Connective Tissue Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id HP:0001574   HP:0002715   HP:0002664   HP:0001871  
Human Phenotype Ontology TermAbnormality of the integument; Abnormality of the immune system; Neoplasm; Abnormality of blood and blood-forming tissues
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O14618 BXGT004076 Copper chaperone for superoxide dismutase 9973 reviewed Enzyme
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O43464 BXGT004595 Serine protease HTRA2, mitochondrial 27429 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05412 BXGT006354 Transcription factor AP-1 3725 reviewed Transcription factor
P06748 BXGT006497 Nucleophosmin 4869 reviewed Chaperone
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P08700 BXGT006816 Interleukin-3 3562 reviewed
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P13236 BXGT007891 C-C motif chemokine 4 6351 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15144 BXGT008087 Aminopeptidase N 290 reviewed Enzyme
P15336 BXGT008109 Cyclic AMP-dependent transcription factor ATF-2 1386 reviewed Transcription factor
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16070 BXGT008186 CD44 antigen 960 reviewed
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 1131 reviewed G-protein coupled receptor
P20936 BXGT008619 Ras GTPase-activating protein 1 5921 reviewed Enzyme modulator
P21583 BXGT008667 Kit ligand 4254 reviewed
P23193 BXGT008834 Transcription elongation factor A protein 1 6917 reviewed Nucleic acid binding
P25103 BXGT009020 Substance-P receptor 6869 reviewed G-protein coupled receptor
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P28908 BXGT009302 Tumor necrosis factor receptor superfamily member 8 943 reviewed
P30536 BXGT009435 Translocator protein 706 reviewed
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P60568 BXGT011315 Interleukin-2 3558 reviewed
P63208 BXGT011507 S-phase kinase-associated protein 1 6500 reviewed Enzyme
P98066 BXGT012225 Tumor necrosis factor-inducible gene 6 protein 7130 reviewed
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q04609 BXGT012768 Glutamate carboxypeptidase 2 2346 reviewed Enzyme
Q05397 BXGT012815 Focal adhesion kinase 1 5747 reviewed Kinase
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 3757 reviewed Ion channel
Q13418 BXGT013351 Integrin-linked protein kinase 3611 reviewed Kinase
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15369 BXGT013560 Elongin-C 6921 reviewed Enzyme modulator
Q15370 BXGT013561 Elongin-B 6923 reviewed Transcription factor
Q15392 BXGT013566 Delta(24)-sterol reductase 1718 reviewed Enzyme
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q7L5Y1 BXGT016996 Mitochondrial enolase superfamily member 1 55556 reviewed Enzyme
Q92743 BXGT019368 Serine protease HTRA1 5654 reviewed Enzyme
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q9HD26 BXGT020540 Golgi-associated PDZ and coiled-coil motif-containing protein 57120 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UKV8 BXGT021752 Protein argonaute-2 27161 reviewed
Q9Y6D6 BXGT022326 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 10565 reviewed
P09622 BXGT023116 Dihydrolipoyl dehydrogenase, mitochondrial 1738 reviewed Enzyme
Q9UM82 BXGT023181 Spermatogenesis-associated protein 2 9825 reviewed
P19875 BXGT023294 C-X-C motif chemokine 2 2920 reviewed Signaling
Q14186 BXGT023367 Transcription factor Dp-1 7027 reviewed Nucleic acid binding
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q12888 BXGT024878 TP53-binding protein 1 7158 reviewed Epigenetic regulator
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease