Showing entry for Testicular Germ Cell Tumor


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD012852
Disease NameTesticular Germ Cell Tumor
Disease CUI IdC1336708
MeSH Codes C04   C12   C19  
Disease Class NameNeoplasms; Male Urogenital Diseases; Endocrine System Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00522 BXGT003935 Krev interaction trapped protein 1 889 reviewed
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O60658 BXGT004890 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A 5151 reviewed
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O94804 BXGT005334 Serine/threonine-protein kinase 10 6793 reviewed Kinase
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01215 BXGT005743 Glycoprotein hormones alpha chain 1081 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P08100 BXGT006725 Rhodopsin 6010 reviewed G-protein coupled receptor
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P0DP23 BXGT007520 Calmodulin-1 808 reviewed
P0DP24 BXGT007521 Calmodulin-2 808 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10398 BXGT007564 Serine/threonine-protein kinase A-Raf 369 reviewed Kinase
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P12830 BXGT007852 Cadherin-1 999 reviewed
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14923 BXGT008069 Junction plakoglobin 3728 reviewed
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P21583 BXGT008667 Kit ligand 4254 reviewed
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P23945 BXGT008931 Follicle-stimulating hormone receptor 2492 reviewed G-protein coupled receptor
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28908 BXGT009302 Tumor necrosis factor receptor superfamily member 8 943 reviewed
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P32320 BXGT009622 Cytidine deaminase 978 reviewed Enzyme
P35613 BXGT009856 Basigin 682 reviewed
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P43026 BXGT010351 Growth/differentiation factor 5 8200 reviewed Signaling
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P47895 BXGT010593 Aldehyde dehydrogenase family 1 member A3 220 reviewed Enzyme
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49419 BXGT010705 Alpha-aminoadipic semialdehyde dehydrogenase 501 reviewed Enzyme
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P61224 BXGT011370 Ras-related protein Rap-1b 5908 reviewed Enzyme modulator
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q02224 BXGT012643 Centromere-associated protein E 1062 reviewed Cellular structure
Q14451 BXGT013471 Growth factor receptor-bound protein 7 2886 reviewed Receptor
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q16611 BXGT013644 Bcl-2 homologous antagonist/killer 578 reviewed Signaling
Q6PCD5 BXGT016464 E3 ubiquitin-protein ligase RFWD3 55159 reviewed Enzyme
Q8IWB6 BXGT018354 Inactive serine/threonine-protein kinase TEX14 56155 reviewed Kinase
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92772 BXGT019371 Cyclin-dependent kinase-like 2 8999 reviewed Kinase
Q96NN9 BXGT019700 Apoptosis-inducing factor 3 150209 reviewed Enzyme
Q96Q89 BXGT019716 Kinesin-like protein KIF20B 9585 reviewed Cellular structure
Q9BXT4 BXGT020175 Tudor domain-containing protein 1 56165 reviewed Enzyme
Q9BZX2 BXGT020204 Uridine-cytidine kinase 2 7371 reviewed Kinase
Q9H008 BXGT020431 Phospholysine phosphohistidine inorganic pyrophosphate phosphatase 64077 reviewed Enzyme
Q9H0U4 BXGT020443 Ras-related protein Rab-1B 81876 reviewed
Q9HCR9 BXGT020537 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 50940 reviewed
Q9NRW1 BXGT021194 Ras-related protein Rab-6B 51560 reviewed
Q9UH17 BXGT021691 DNA dC->dU-editing enzyme APOBEC-3B 9582 reviewed Enzyme
Q9UJW3 BXGT021732 DNA (cytosine-5)-methyltransferase 3-like 29947 reviewed
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9UKV8 BXGT021752 Protein argonaute-2 27161 reviewed
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
Q7Z624 BXGT022792 Calmodulin-lysine N-methyltransferase 79823 reviewed
P61204 BXGT024318 ADP-ribosylation factor 3 377 reviewed
P0DP25 BXGT024595 Calmodulin-3 808 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease