Showing entry for DNA (cytosine-5)-methyltransferase 3-like


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021732
Protein NameDNA (cytosine-5)-methyltransferase 3-like
Uniport IdQ9UJW3
GeneDNMT3L
Gene Id29947
DomainADD_DNMT3
Pfam PF17980  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006306 DNA methylation
Biological Process GO:0043046 DNA methylation involved in gamete generation
Biological Process GO:0032776 DNA methylation on cytosine
Biological Process GO:0007141 male meiosis I
Biological Process GO:1905642 negative regulation of DNA methylation
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:1905643 positive regulation of DNA methylation
Biological Process GO:0006349 regulation of gene expression by genetic imprinting
Biological Process GO:0007283 spermatogenesis
Biological Process GO:0048863 stem cell differentiation
molecular function GO:0008047 enzyme activator activity
molecular function GO:0019899 enzyme binding
molecular function GO:0046872 metal ion binding
cellular component GO:0005829 cytosol
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-212165 Epigenetic regulation of gene expression
R-HSA-5334118 DNA methylation
R-HSA-74160 Gene expression (Transcription)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004509 BXGD000275 Azoospermia Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008412 BXGD000538 Choline Deficiency Nutritional and Metabolic Diseases
C0008497 BXGD000549 Choriocarcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0014145 BXGD000901 Yolk Sac Tumor Neoplasms
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0021364 BXGD001500 Male infertility Male Urogenital Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0024408 BXGD001768 Machado-Joseph Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036631 BXGD002626 Seminoma Neoplasms
C0039538 BXGD002819 Teratoma Neoplasms
C0156344 BXGD003851 Endometriosis of ovary Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0205851 BXGD004132 Germ cell tumor Neoplasms
C0206659 BXGD004222 Embryonal Carcinoma Neoplasms
C0234985 BXGD004708 Mental deterioration Mental Disorders
C0235946 BXGD004789 Cerebral atrophy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0269102 BXGD006053 Endometrioma Female Urogenital Diseases and Pregnancy Complications
C0279671 BXGD006677 Cervical Squamous Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0796663 BXGD010837 Childhood Testicular Germ Cell Tumor Neoplasms; Male Urogenital Diseases; Endocrine System Diseases
C1270972 BXGD012006 Mild cognitive disorder Mental Disorders
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332221 BXGD012514 Adult Yolk Sac Tumor Neoplasms
C1335059 BXGD012755 testicular nonseminoma
C1336708 BXGD012852 Testicular Germ Cell Tumor Neoplasms; Male Urogenital Diseases; Endocrine System Diseases
C1368898 BXGD012904 Adult Teratoma Neoplasms
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1536148 BXGD013338 Chocolate cyst of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1827434 BXGD013772 Seminoma of testis, stage 1 Neoplasms
C2347762 BXGD017050 Childhood Teratoma Neoplasms
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4551584 BXGD023362 Brain atrophy Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005624 Genistein 270.24
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein