Showing entry for Ezrin


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008106
Protein NameEzrin
Uniport IdP15311
GeneEZR
Gene Id7430
DomainERM; FERM_C; FERM_M; FERM_N
Pfam PF00769   PF09380   PF00373   PF09379  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04530 Tight junction
5. Organismal Systems 5.1 Immune system hsa04670 Leukocyte transendothelial migration
4. Cellular Processes 4.5 Cell motility hsa04810 Regulation of actin cytoskeleton
5. Organismal Systems 5.4 Digestive system hsa04971 Gastric acid secretion
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05130 Pathogenic Escherichia coli infection
6. Human Diseases 6.1 Cancers: Overview hsa05205 Proteoglycans in cancer
6. Human Diseases 6.1 Cancers: Overview hsa05206 MicroRNAs in cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031532 actin cytoskeleton reorganization
Biological Process GO:0051017 actin filament bundle assembly
Biological Process GO:0030953 astral microtubule organization
Biological Process GO:0007411 axon guidance
Biological Process GO:0034629 cellular protein-containing complex localization
Biological Process GO:0071320 cellular response to cAMP
Biological Process GO:0043622 cortical microtubule organization
Biological Process GO:0051660 establishment of centrosome localization
Biological Process GO:0061028 establishment of endothelial barrier
Biological Process GO:0035088 establishment or maintenance of apical/basal cell polarity
Biological Process GO:0046847 filopodium assembly
Biological Process GO:0001951 intestinal D-glucose absorption
Biological Process GO:0007159 leukocyte cell-cell adhesion
Biological Process GO:0022614 membrane to membrane docking
Biological Process GO:0030033 microvillus assembly
Biological Process GO:0070373 negative regulation of ERK1 and ERK2 cascade
Biological Process GO:0032703 negative regulation of interleukin-2 production
Biological Process GO:1903753 negative regulation of p38MAPK cascade
Biological Process GO:0050860 negative regulation of T cell receptor signaling pathway
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0048015 phosphatidylinositol-mediated signaling
Biological Process GO:1903364 positive regulation of cellular protein catabolic process
Biological Process GO:2000643 positive regulation of early endosome to late endosome transport
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0040018 positive regulation of multicellular organism growth
Biological Process GO:1902966 positive regulation of protein localization to early endosome
Biological Process GO:1903078 positive regulation of protein localization to plasma membrane
Biological Process GO:0050714 positive regulation of protein secretion
Biological Process GO:0010737 protein kinase A signaling
Biological Process GO:0072697 protein localization to cell cortex
Biological Process GO:0072659 protein localization to plasma membrane
Biological Process GO:0031623 receptor internalization
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0032532 regulation of microvillus length
Biological Process GO:1902115 regulation of organelle assembly
Biological Process GO:0003376 sphingosine-1-phosphate receptor signaling pathway
Biological Process GO:1902896 terminal web assembly
molecular function GO:0003779 actin binding
molecular function GO:0051015 actin filament binding
molecular function GO:0051117 ATPase binding
molecular function GO:0045296 cadherin binding
molecular function GO:0050839 cell adhesion molecule binding
molecular function GO:0097718 disordered domain specific binding
molecular function GO:0042802 identical protein binding
molecular function GO:0008017 microtubule binding
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0051018 protein kinase A binding
molecular function GO:0034236 protein kinase A catalytic subunit binding
molecular function GO:0034237 protein kinase A regulatory subunit binding
molecular function GO:0003723 RNA binding
molecular function GO:0044548 S100 protein binding
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0005884 actin filament
cellular component GO:0045177 apical part of cell
cellular component GO:0016324 apical plasma membrane
cellular component GO:0097449 astrocyte projection
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0005903 brush border
cellular component GO:0044297 cell body
cellular component GO:0071944 cell periphery
cellular component GO:0042995 cell projection
cellular component GO:0051286 cell tip
cellular component GO:0036064 ciliary basal body
cellular component GO:0030863 cortical cytoskeleton
cellular component GO:0005737 cytoplasm
cellular component GO:0098592 cytoplasmic side of apical plasma membrane
cellular component GO:0005829 cytosol
cellular component GO:0005768 endosome
cellular component GO:0070062 extracellular exosome
cellular component GO:0005615 extracellular space
cellular component GO:0019898 extrinsic component of membrane
cellular component GO:0001650 fibrillar center
cellular component GO:0030175 filopodium
cellular component GO:0005925 focal adhesion
cellular component GO:0001772 immunological synapse
cellular component GO:0071437 invadopodium
cellular component GO:0016020 membrane
cellular component GO:0044393 microspike
cellular component GO:0005902 microvillus
cellular component GO:0031528 microvillus membrane
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0044853 plasma membrane raft
cellular component GO:0032991 protein-containing complex
cellular component GO:0001726 ruffle
cellular component GO:0032587 ruffle membrane
cellular component GO:0097454 Schwann cell microvillus
cellular component GO:0030315 T-tubule
cellular component GO:0001931 uropod
cellular component GO:0031982 vesicle
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-1266738 Developmental Biology
R-HSA-373752 Netrin-1 signaling
R-HSA-373760 L1CAM interactions
R-HSA-373760 L1CAM interactions
R-HSA-422475 Axon guidance
R-HSA-422475 Axon guidance
R-HSA-437239 Recycling pathway of L1
R-HSA-437239 Recycling pathway of L1
R-HSA-9675108 Nervous system development
R-HSA-9675108 Nervous system development
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001857 BXGD000085 AIDS related complex Infections; Immune System Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002448 BXGD000115 Ameloblastoma Neoplasms
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007113 BXGD000430 Rectal Carcinoma Digestive System Diseases; Neoplasms
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007860 BXGD000495 Uterine Cervicitis Female Urogenital Diseases and Pregnancy Complications
C0008354 BXGD000533 Cholera Infections
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0008489 BXGD000546 Chorea Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0008497 BXGD000549 Choriocarcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0013371 BXGD000823 Shigella Infections Digestive System Diseases; Infections
C0013384 BXGD000826 Dyskinetic syndrome Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013421 BXGD000837 Dystonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015625 BXGD001006 Fanconi Anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0016034 BXGD001034 Breast Fibrocystic Disease Skin and Connective Tissue Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0017661 BXGD001139 IGA Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0018498 BXGD001195 Hair Color
C0020796 BXGD001468 Profound Mental Retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0021125 BXGD001483 Impulsive Behavior Behavior and Behavior Mechanisms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023281 BXGD001628 Leishmaniasis Infections; Skin and Connective Tissue Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024131 BXGD001736 Lupus Vulgaris Infections; Skin and Connective Tissue Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024232 BXGD001751 Lymphatic Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0024523 BXGD001781 Malabsorption Syndrome Digestive System Diseases; Nutritional and Metabolic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024667 BXGD001794 Animal Mammary Neoplasms Neoplasms; Animal Diseases
C0024668 BXGD001795 Mammary Neoplasms, Experimental Neoplasms
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026106 BXGD001889 Mild Mental Retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026351 BXGD001900 Moderate intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027809 BXGD002040 Neurilemmoma Neoplasms
C0027832 BXGD002048 Neurofibromatosis 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0028880 BXGD002097 Odontogenic Tumors Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0035204 BXGD002511 Respiration Disorders Respiratory Tract Diseases
C0035369 BXGD002543 Retroviridae Infections Infections
C0035412 BXGD002548 Rhabdomyosarcoma Neoplasms
C0036117 BXGD002577 Salmonella infections Infections
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0036646 BXGD002627 Age-related cataract Eye Diseases
C0036857 BXGD002638 Severe intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0037317 BXGD002689 Sleep disturbances Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0038271 BXGD002742 Stereotyped Behavior Behavior and Behavior Mechanisms
C0038273 BXGD002743 Stereotypic Movement Disorder Mental Disorders
C0039101 BXGD002790 synovial sarcoma Neoplasms
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0079588 BXGD003084 Ichthyosis, X-Linked Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0086743 BXGD003308 Osteoarthrosis Deformans Musculoskeletal Diseases
C0151468 BXGD003424 Thyroid Gland Follicular Adenoma Neoplasms; Endocrine System Diseases
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151785 BXGD003474 Disease of mucous membrane Pathological Conditions, Signs and Symptoms
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0153349 BXGD003621 Malignant neoplasm of tongue Neoplasms; Stomatognathic Diseases
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205647 BXGD004099 Follicular adenoma Neoplasms
C0205696 BXGD004107 Anaplastic carcinoma Neoplasms
C0205697 BXGD004108 Carcinoma, Spindle-Cell Neoplasms
C0205698 BXGD004109 Undifferentiated carcinoma Neoplasms
C0205699 BXGD004110 Carcinomatosis Neoplasms
C0206062 BXGD004148 Lung Diseases, Interstitial Respiratory Tract Diseases
C0206682 BXGD004237 Follicular thyroid carcinoma Neoplasms
C0206687 BXGD004242 Carcinoma, Endometrioid Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0206708 BXGD004256 Cervical Intraepithelial Neoplasia Neoplasms
C0220611 BXGD004295 Childhood Rhabdomyosarcoma Neoplasms
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0234533 BXGD004687 Generalized seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0235946 BXGD004789 Cerebral atrophy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0238232 BXGD004896 Polyp of larynx Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0262630 BXGD005262 Reduced concentration span Behavior and Behavior Mechanisms
C0266464 BXGD005676 Polymicrogyria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0270922 BXGD006134 Peripheral demyelinating neuropathy Immune System Diseases; Nervous System Diseases
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278512 BXGD006528 Metastatic osteosarcoma Neoplasms
C0278660 BXGD006555 Adult Synovial Sarcoma Neoplasms
C0278704 BXGD006567 Malignant Childhood Neoplasm Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279546 BXGD006633 Adult Undifferentiated Pleomorphic Sarcoma Neoplasms
C0279550 BXGD006635 Adult Rhabdomyosarcoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0279982 BXGD006702 Childhood Synovial Sarcoma Neoplasms
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280232 BXGD006724 stage, cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0280324 BXGD006740 Laryngeal Squamous Cell Carcinoma Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0281361 BXGD006774 Adenocarcinoma of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0282612 BXGD006820 Prostatic Intraepithelial Neoplasias Neoplasms
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333293 BXGD006942 Healing ulcer Pathological Conditions, Signs and Symptoms
C0333516 BXGD006957 Tumor necrosis Pathological Conditions, Signs and Symptoms
C0334463 BXGD007076 Malignant Fibrous Histiocytoma Neoplasms
C0338106 BXGD007167 Adenocarcinoma of colon Digestive System Diseases; Neoplasms
C0341306 BXGD007401 Microvillus inclusion disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0342257 BXGD007447 Complications of Diabetes Mellitus Endocrine System Diseases
C0344482 BXGD007678 Hypoplasia of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0346053 BXGD007770 Atypical fibroxanthoma of skin Neoplasms
C0346398 BXGD007822 Mixed follicular and papillary thyroid carcinoma
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349566 BXGD007928 Squamous cell carcinoma of tongue Neoplasms; Stomatognathic Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0393819 BXGD008151 Polyradiculoneuropathy, Chronic Inflammatory Demyelinating Immune System Diseases; Nervous System Diseases
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0424503 BXGD008532 Dysmorphic facies
C0431371 BXGD008676 Absence of septum pellucidum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0431380 BXGD008680 Cortical Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0454644 BXGD008850 Delayed speech and language development Behavior and Behavior Mechanisms
C0474808 BXGD008959 Follicular neoplasm Neoplasms
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0520947 BXGD009126 Clumsiness - motor delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0521158 BXGD009130 Recurrent tumor
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0553580 BXGD009399 Ewings sarcoma Neoplasms
C0553723 BXGD009416 Squamous cell carcinoma of skin Neoplasms; Skin and Connective Tissue Diseases
C0557874 BXGD009444 Global developmental delay
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598935 BXGD009674 Tumor Initiation Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0677944 BXGD009738 Sentinel node (disorder)
C0677948 BXGD009739 Stage II Colorectal Cancer Digestive System Diseases; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0684276 BXGD009793 Hypsarrhythmia Nervous System Diseases
C0685938 BXGD009829 Malignant neoplasm of gastrointestinal tract Digestive System Diseases; Neoplasms
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699949 BXGD009872 airway disease Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0700201 BXGD009880 Dyssomnias Nervous System Diseases; Mental Disorders
C0730328 BXGD009959 Central Serous Chorioretinopathy Eye Diseases
C0744869 BXGD010109 Metastatic hepatocellular carcinoma Digestive System Diseases; Neoplasms
C0751495 BXGD010473 Seizures, Focal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0856975 BXGD011127 Autistic behavior Behavior and Behavior Mechanisms
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0949664 BXGD011583 Tauopathies Nervous System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168327 BXGD011787 High-Grade Prostatic Intraepithelial Neoplasia Neoplasms; Male Urogenital Diseases
C1257925 BXGD011814 Mammary Carcinoma, Animal Neoplasms; Animal Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1270972 BXGD012006 Mild cognitive disorder Mental Disorders
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1319315 BXGD012415 Adenocarcinoma of large intestine Digestive System Diseases; Neoplasms
C1332201 BXGD012502 Adult Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1334274 BXGD012695 Invasive Carcinoma Neoplasms
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1512127 BXGD013185 HER2 gene amplification
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1527349 BXGD013277 Ductal Breast Carcinoma Neoplasms
C1527366 BXGD013280 Salaam Seizures Nervous System Diseases
C1563719 BXGD013392 Kallmann Syndrome 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1704321 BXGD013544 Nephrotic Syndrome, Minimal Change Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1848207 BXGD014916 Poor speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1849157 BXGD015018 Resistance to Insulin-Like Growth Factor I Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1849718 BXGD015080 POPLITEAL PTERYGIUM SYNDROME, LETHAL TYPE Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases; Stomatognathic Diseases
C1854301 BXGD015391 Motor delay Mental Disorders
C1856689 BXGD015630 FRIEDREICH ATAXIA 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1859470 BXGD015896 Large basal ganglia
C1960398 BXGD016658 HER2-positive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C2044987 BXGD016890 Cervical Glandular Intraepithelial Neoplasia Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363741 BXGD017100 HIV-1 infection
C2717836 BXGD017510 Steroid Sulfatase Deficiency Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2945695 BXGD018187 Limb ischemia
C2945759 BXGD018189 aggressive cancer
C3146252 BXGD018261 Stage II Colorectal Cancer AJCC v7
C3469521 BXGD018910 FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3642345 BXGD019244 Luminal A Breast Carcinoma
C3695127 BXGD019344 Astrocytoma of brain Neoplasms; Nervous System Diseases
C3714514 BXGD019409 Infection Infections
C3714524 BXGD019410 Fibromyxosarcoma Neoplasms
C3714651 BXGD019423 Follicular Variant Thyroid Gland Papillary Carcinoma Neoplasms; Endocrine System Diseases
C3810365 BXGD019652 Central visual impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3899638 BXGD020085 Childhood Undifferentiated Pleomorphic Sarcoma Neoplasms
C4021219 BXGD020582 Multifocal epileptiform discharges
C4048268 BXGD021896 Cortical visual impairment Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4049711 BXGD021949 Lepidic Predominant Adenocarcinoma Neoplasms
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4277690 BXGD022377 Ciliopathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C4329990 BXGD022796 Feline Osteosarcoma
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
C4551687 BXGD023392 Sarcoma of soft tissue Neoplasms
C4553743 BXGD023548 Spasticity, CTCAE
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0007029 Emodin 270.24
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein