Showing entry for DCC-interacting protein 13-beta


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022976
Protein NameDCC-interacting protein 13-beta
Uniport IdQ8NEU8
GeneAPPL2
Gene Id55198
DomainBAR_3; PH; PID
Pfam PF00169   PF00640  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0033211 adiponectin-activated signaling pathway
Biological Process GO:0007049 cell cycle
Biological Process GO:0035729 cellular response to hepatocyte growth factor stimulus
Biological Process GO:0009631 cold acclimation
Biological Process GO:0002024 diet induced thermogenesis
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:1900077 negative regulation of cellular response to insulin stimulus
Biological Process GO:1900016 negative regulation of cytokine production involved in inflammatory response
Biological Process GO:0046322 negative regulation of fatty acid oxidation
Biological Process GO:0046325 negative regulation of glucose import
Biological Process GO:2000178 negative regulation of neural precursor cell proliferation
Biological Process GO:0050768 negative regulation of neurogenesis
Biological Process GO:0120162 positive regulation of cold-induced thermogenesis
Biological Process GO:1905451 positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
Biological Process GO:1905303 positive regulation of macropinocytosis
Biological Process GO:0060100 positive regulation of phagocytosis, engulfment
Biological Process GO:0051289 protein homotetramerization
Biological Process GO:0006606 protein import into nucleus
Biological Process GO:0010762 regulation of fibroblast migration
Biological Process GO:2000045 regulation of G1/S transition of mitotic cell cycle
Biological Process GO:0045088 regulation of innate immune response
Biological Process GO:0034143 regulation of toll-like receptor 4 signaling pathway
Biological Process GO:0023052 signaling
Biological Process GO:0007165 signal transduction
Biological Process GO:0007179 transforming growth factor beta receptor signaling pathway
molecular function GO:0042802 identical protein binding
molecular function GO:0035091 phosphatidylinositol binding
molecular function GO:0001786 phosphatidylserine binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0031901 early endosome membrane
cellular component GO:0032009 early phagosome
cellular component GO:0036186 early phagosome membrane
cellular component GO:0005768 endosome
cellular component GO:0010008 endosome membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0044354 macropinosome
cellular component GO:0016020 membrane
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0001726 ruffle
cellular component GO:0032587 ruffle membrane
cellular component GO:0031982 vesicle
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004936 BXGD000295 Mental disorders Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013146 BXGD000801 Drug abuse Chemically-Induced Disorders; Mental Disorders
C0013170 BXGD000802 Drug habituation Chemically-Induced Disorders; Mental Disorders
C0013222 BXGD000805 Drug Use Disorders Chemically-Induced Disorders; Mental Disorders
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029231 BXGD002125 Organic Mental Disorders, Substance-Induced Chemically-Induced Disorders; Mental Disorders
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0038580 BXGD002771 Substance Dependence Chemically-Induced Disorders; Mental Disorders
C0038586 BXGD002772 Substance Use Disorders Chemically-Induced Disorders; Mental Disorders
C0236969 BXGD004842 Substance-Related Disorders Chemically-Induced Disorders; Mental Disorders
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0740858 BXGD010012 Substance abuse problem Chemically-Induced Disorders; Mental Disorders
C0860603 BXGD011236 Anxiety symptoms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1510472 BXGD013170 Drug Dependence Chemically-Induced Disorders; Mental Disorders
C1561826 BXGD013364 Overweight and obesity
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2945759 BXGD018189 aggressive cancer
C4316881 BXGD022709 Prescription Drug Abuse Chemically-Induced Disorders; Mental Disorders
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein