Showing entry for P2X purinoceptor 7


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019935
Protein NameP2X purinoceptor 7
Uniport IdQ99572
GeneP2RX7
Gene Id5027
DomainP2X_receptor
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04020 Calcium signaling pathway
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
5. Organismal Systems 5.1 Immune system hsa04621 NOD-like receptor signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0097190 apoptotic signaling pathway
Biological Process GO:0032060 bleb assembly
Biological Process GO:0007596 blood coagulation
Biological Process GO:0070588 calcium ion transmembrane transport
Biological Process GO:0035585 calcium-mediated signaling using extracellular calcium source
Biological Process GO:0000902 cell morphogenesis
Biological Process GO:0007166 cell surface receptor signaling pathway
Biological Process GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling
Biological Process GO:0071318 cellular response to ATP
Biological Process GO:0071359 cellular response to dsRNA
Biological Process GO:0031668 cellular response to extracellular stimulus
Biological Process GO:0046513 ceramide biosynthetic process
Biological Process GO:0032963 collagen metabolic process
Biological Process GO:0050830 defense response to Gram-positive bacterium
Biological Process GO:0097191 extrinsic apoptotic signaling pathway
Biological Process GO:0048873 homeostasis of number of cells within a tissue
Biological Process GO:0006954 inflammatory response
Biological Process GO:0051899 membrane depolarization
Biological Process GO:0006509 membrane protein ectodomain proteolysis
Biological Process GO:0007005 mitochondrion organization
Biological Process GO:0043132 NAD transport
Biological Process GO:0045779 negative regulation of bone resorption
Biological Process GO:0045794 negative regulation of cell volume
Biological Process GO:0043409 negative regulation of MAPK cascade
Biological Process GO:0001845 phagolysosome assembly
Biological Process GO:0006649 phospholipid transfer to membrane
Biological Process GO:0017121 plasma membrane phospholipid scrambling
Biological Process GO:0046931 pore complex assembly
Biological Process GO:1904172 positive regulation of bleb assembly
Biological Process GO:0030501 positive regulation of bone mineralization
Biological Process GO:0010524 positive regulation of calcium ion transport into cytosol
Biological Process GO:0050715 positive regulation of cytokine secretion
Biological Process GO:0051495 positive regulation of cytoskeleton organization
Biological Process GO:0014054 positive regulation of gamma-aminobutyric acid secretion
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0014049 positive regulation of glutamate secretion
Biological Process GO:0045821 positive regulation of glycolytic process
Biological Process GO:0032730 positive regulation of interleukin-1 alpha production
Biological Process GO:0032731 positive regulation of interleukin-1 beta production
Biological Process GO:0032755 positive regulation of interleukin-6 production
Biological Process GO:0034767 positive regulation of ion transmembrane transport
Biological Process GO:0070230 positive regulation of lymphocyte apoptotic process
Biological Process GO:0051901 positive regulation of mitochondrial depolarization
Biological Process GO:0032308 positive regulation of prostaglandin secretion
Biological Process GO:0001916 positive regulation of T cell mediated cytotoxicity
Biological Process GO:0030163 protein catabolic process
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0016485 protein processing
Biological Process GO:0035590 purinergic nucleotide receptor signaling pathway
Biological Process GO:0072593 reactive oxygen species metabolic process
Biological Process GO:0051709 regulation of killing of cells of other organism
Biological Process GO:0002028 regulation of sodium ion transport
Biological Process GO:0051209 release of sequestered calcium ion into cytosol
Biological Process GO:0033198 response to ATP
Biological Process GO:0051592 response to calcium ion
Biological Process GO:0042493 response to drug
Biological Process GO:0051602 response to electrical stimulus
Biological Process GO:0034405 response to fluid shear stress
Biological Process GO:0002931 response to ischemia
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0009612 response to mechanical stimulus
Biological Process GO:0010043 response to zinc ion
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0048705 skeletal system morphogenesis
Biological Process GO:0016079 synaptic vesicle exocytosis
Biological Process GO:0043029 T cell homeostasis
Biological Process GO:0042098 T cell proliferation
Biological Process GO:0006900 vesicle budding from membrane
molecular function GO:0005524 ATP binding
molecular function GO:0004931 extracellularly ATP-gated cation channel activity
molecular function GO:0042802 identical protein binding
molecular function GO:0001530 lipopolysaccharide binding
molecular function GO:0001614 purinergic nucleotide receptor activity
molecular function GO:0005102 signaling receptor binding
cellular component GO:0032059 bleb
cellular component GO:0005911 cell-cell junction
cellular component GO:0005737 cytoplasm
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0005639 integral component of nuclear inner membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0031594 neuromuscular junction
cellular component GO:0043025 neuronal cell body
cellular component GO:0005886 plasma membrane
cellular component GO:0098794 postsynapse
cellular component GO:0098793 presynapse
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-139853 Elevation of cytosolic Ca2+ levels
R-HSA-1643685 Disease
R-HSA-168249 Innate Immune System
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168256 Immune System
R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
R-HSA-418346 Platelet homeostasis
R-HSA-418360 Platelet calcium homeostasis
R-HSA-5663205 Infectious disease
R-HSA-622312 Inflammasomes
R-HSA-622312 Inflammasomes
R-HSA-844456 The NLRP3 inflammasome
R-HSA-844456 The NLRP3 inflammasome
R-HSA-9658195 Leishmania infection
R-HSA-9660826 Purinergic signaling in leishmaniasis infection
R-HSA-9664424 Cell recruitment (pro-inflammatory response)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001339 BXGD000041 Acute pancreatitis Digestive System Diseases
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001818 BXGD000080 Agoraphobia Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003862 BXGD000230 Arthralgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003868 BXGD000233 Arthritis, Gouty Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0003886 BXGD000238 Arthrogryposis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004610 BXGD000281 Bacteremia Pathological Conditions, Signs and Symptoms; Infections
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005587 BXGD000316 Depression, Bipolar Mental Disorders
C0005940 BXGD000352 Bone Diseases Musculoskeletal Diseases
C0006012 BXGD000360 Borderline Personality Disorder Mental Disorders
C0006111 BXGD000369 Brain Diseases Nervous System Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006287 BXGD000390 Bronchopulmonary Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007194 BXGD000452 Hypertrophic Cardiomyopathy Cardiovascular Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007682 BXGD000471 CNS disorder Nervous System Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008149 BXGD000520 Chlamydia Infections Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009952 BXGD000639 Febrile Convulsions Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011311 BXGD000714 Dengue Fever Infections
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011644 BXGD000744 Scleroderma Skin and Connective Tissue Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0013264 BXGD000808 Muscular Dystrophy, Duchenne Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0014038 BXGD000878 Encephalitis Nervous System Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0014558 BXGD000933 Uncinate Epilepsy Nervous System Diseases
C0014772 BXGD000948 Red Blood Cell Count measurement
C0015397 BXGD000983 Disorder of eye Eye Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0017168 BXGD001101 Gastroesophageal reflux disease Digestive System Diseases
C0017601 BXGD001125 Glaucoma Eye Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0017658 BXGD001138 Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020429 BXGD001378 Hyperalgesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020507 BXGD001413 Hyperplasia Pathological Conditions, Signs and Symptoms
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020630 BXGD001454 Hypophosphatasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0021053 BXGD001476 Immune System Diseases Immune System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0021831 BXGD001516 Intestinal Diseases Digestive System Diseases
C0022408 BXGD001544 Arthropathy Musculoskeletal Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022680 BXGD001576 Polycystic Kidney Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023283 BXGD001629 Leishmaniasis, Cutaneous Infections; Skin and Connective Tissue Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023470 BXGD001659 Myeloid Leukemia Neoplasms
C0023896 BXGD001718 Alcoholic Liver Diseases Digestive System Diseases; Chemically-Induced Disorders
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024131 BXGD001736 Lupus Vulgaris Infections; Skin and Connective Tissue Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024232 BXGD001751 Lymphatic Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024305 BXGD001763 Lymphoma, Non-Hodgkin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024530 BXGD001783 Malaria Infections
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026850 BXGD001942 Muscular Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026857 BXGD001943 Musculoskeletal Diseases Musculoskeletal Diseases
C0026896 BXGD001946 Myasthenia Gravis Neoplasms; Immune System Diseases; Nervous System Diseases
C0026918 BXGD001948 Mycobacterium Infections Infections
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027404 BXGD001984 Narcolepsy Nervous System Diseases; Mental Disorders
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028768 BXGD002084 Obsessive-Compulsive Disorder Mental Disorders
C0028790 BXGD002085 Cerebral artery occlusion Nervous System Diseases; Cardiovascular Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030201 BXGD002194 Pain, Postoperative Pathological Conditions, Signs and Symptoms
C0030286 BXGD002201 Pancreatic Diseases Digestive System Diseases
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0030499 BXGD002232 Parasitic Diseases Infections
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031046 BXGD002275 Pericarditis Cardiovascular Diseases
C0031090 BXGD002280 Periodontal Diseases Stomatognathic Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0032584 BXGD002363 polyps Pathological Conditions, Signs and Symptoms
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0035851 BXGD002567 Root Resorption Stomatognathic Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037023 BXGD002660 Sialadenitis Stomatognathic Diseases
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0037286 BXGD002681 Skin Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C0037317 BXGD002689 Sleep disturbances Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038436 BXGD002755 Post-Traumatic Stress Disorder Mental Disorders
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0040558 BXGD002873 Toxoplasmosis Infections
C0040997 BXGD002894 Trigeminal Neuralgia Nervous System Diseases; Stomatognathic Diseases
C0041234 BXGD002901 Chagas Disease Infections
C0041296 BXGD002903 Tuberculosis Infections
C0041327 BXGD002916 Tuberculosis, Pulmonary Infections; Respiratory Tract Diseases
C0041330 BXGD002917 Tuberculosis, Spinal Infections; Musculoskeletal Diseases
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0042164 BXGD002965 Uveitis Eye Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0085315 BXGD003158 Toxoplasmosis, Cerebral Infections; Nervous System Diseases
C0085413 BXGD003171 Polycystic Kidney, Autosomal Dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0085548 BXGD003183 Autosomal Recessive Polycystic Kidney Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0149896 BXGD003382 Primary gout Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0150055 BXGD003401 Chronic pain Pathological Conditions, Signs and Symptoms
C0151449 BXGD003419 Primary Sjögren's syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C0151718 BXGD003464 Hypocholesterolemia Nutritional and Metabolic Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0151825 BXGD003481 Bone pain Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0152244 BXGD003571 Bone Cysts, Aneurysmal Neoplasms; Musculoskeletal Diseases
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0154409 BXGD003717 Recurrent major depressive episodes Mental Disorders
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0158252 BXGD003877 Intervertebral disc disorder Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0158266 BXGD003878 Intervertebral Disc Degeneration Musculoskeletal Diseases
C0159020 BXGD003919 Convulsions in the newborn Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0162836 BXGD003990 Hidradenitis Suppurativa Infections; Skin and Connective Tissue Diseases
C0178417 BXGD004025 Anhedonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0220605 BXGD004294 Adult Non-Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220612 BXGD004296 Childhood Non-Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220633 BXGD004303 Uveal melanoma Neoplasms; Eye Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0234251 BXGD004645 Inflammatory pain Pathological Conditions, Signs and Symptoms
C0235272 BXGD004737 Retinal damage Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases; Wounds and Injuries
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0238790 BXGD004956 bone destruction
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0262405 BXGD005237 Cerebral dysfunction Nervous System Diseases
C0262985 BXGD005277 Psoriasiform eczema Skin and Connective Tissue Diseases
C0268800 BXGD006041 Simple renal cyst Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0275518 BXGD006375 Acute infectious disease Pathological Conditions, Signs and Symptoms; Infections
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279530 BXGD006628 Malignant Bone Neoplasm Neoplasms; Musculoskeletal Diseases
C0279671 BXGD006677 Cervical Squamous Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333463 BXGD006954 Senile Plaques Pathological Conditions, Signs and Symptoms
C0338484 BXGD007188 Familial Hemiplegic Migraine Nervous System Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0338831 BXGD007216 Manic Mental Disorders
C0338908 BXGD007218 Mixed anxiety and depressive disorder Mental Disorders
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0345905 BXGD007746 Intrahepatic Cholangiocarcinoma Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376544 BXGD008001 Hematopoietic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0391976 BXGD008022 Pain Disorder Mental Disorders
C0393642 BXGD008111 Sepsis-Associated Encephalopathy Nervous System Diseases
C0393672 BXGD008115 Epilepsy, Benign Psychomotor, Childhood Nervous System Diseases
C0393682 BXGD008117 Epilepsy, Lateral Temporal Nervous System Diseases
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0409980 BXGD008403 Primary antiphospholipid syndrome Immune System Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0432408 BXGD008785 Trisomy 12 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0524528 BXGD009229 Pervasive Development Disorder Mental Disorders
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0549297 BXGD009367 Auricular swelling Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0563625 BXGD009484 Agnosia for Pain Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0574785 BXGD009506 Lower Urinary Tract Symptoms Pathological Conditions, Signs and Symptoms
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0595921 BXGD009626 Intraocular pressure disorder Eye Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0679362 BXGD009767 Tuberculosis, extrapulmonary Infections
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0730285 BXGD009943 Diabetic macular edema Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0740394 BXGD009989 Hyperuricemia Pathological Conditions, Signs and Symptoms
C0746402 BXGD010141 manic symptom
C0748355 BXGD010195 Acute respiratory distress Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0751074 BXGD010313 Diabetic Neuralgia Nervous System Diseases; Endocrine System Diseases
C0751214 BXGD010353 Hyperalgesia, Thermal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751324 BXGD010388 Multiple Sclerosis, Acute Fulminating Immune System Diseases; Nervous System Diseases
C0751964 BXGD010655 Multiple Sclerosis, Primary Progressive Immune System Diseases; Nervous System Diseases
C0752304 BXGD010711 Hypoxic-Ischemic Encephalopathy Nervous System Diseases; Cardiovascular Diseases
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0853193 BXGD010968 Bipolar I disorder Mental Disorders
C0855095 BXGD011071 Small Lymphocytic Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0856169 BXGD011096 Endothelial dysfunction
C0856825 BXGD011118 Acute GVH disease Immune System Diseases
C0876973 BXGD011322 Infectious Lung Disorder Infections; Respiratory Tract Diseases
C0920646 BXGD011471 Ischemia of kidney Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0947785 BXGD011495 [D]Sleep disturbances (& [hypersomnia] or [insomnia])
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1096063 BXGD011600 Drug Resistant Epilepsy Nervous System Diseases
C1141926 BXGD011723 Abdominal sepsis
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1281914 BXGD012135 Corneal allograft rejection
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332225 BXGD012515 Aggressive Non-Hodgkin Lymphoma
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1443892 BXGD013073 Chronic Q Fever Infections
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1562113 BXGD013372 Fleck corneal dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1611743 BXGD013456 Familial (FPAH)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1719494 BXGD013655 PERIODONTITIS, LOCALIZED AGGRESSIVE Stomatognathic Diseases
C1719672 BXGD013659 Severe Sepsis Pathological Conditions, Signs and Symptoms; Infections
C1720983 BXGD013698 Channelopathies Pathological Conditions, Signs and Symptoms
C1839839 BXGD014416 MAJOR AFFECTIVE DISORDER 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Mental Disorders
C1842981 BXGD014547 NEUROTICISM Behavior and Behavior Mechanisms
C1852197 BXGD015264 MAJOR AFFECTIVE DISORDER 1 Mental Disorders
C1864997 BXGD016281 Majeed syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Infections; Musculoskeletal Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C1868678 BXGD016522 THANATOPHORIC DYSPLASIA, TYPE I (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1868683 BXGD016526 B-CELL MALIGNANCY, LOW-GRADE
C1970943 BXGD016852 MAJOR AFFECTIVE DISORDER 4 Mental Disorders
C1970945 BXGD016853 MAJOR AFFECTIVE DISORDER 6 Mental Disorders
C1998028 BXGD016865 Photoreceptor degeneration Eye Diseases
C2062441 BXGD016897 Influenza A
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2242589 BXGD016983 Coronaropathy
C2316810 BXGD017030 Chronic kidney disease stage 5 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2363741 BXGD017100 HIV-1 infection
C2700438 BXGD017469 MAJOR AFFECTIVE DISORDER 7 Mental Disorders
C2700439 BXGD017470 MAJOR AFFECTIVE DISORDER 8 Mental Disorders
C2700440 BXGD017471 MAJOR AFFECTIVE DISORDER 9 Mental Disorders
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2718067 BXGD017523 Alcoholic Steatohepatitis Digestive System Diseases; Chemically-Induced Disorders
C2902981 BXGD017859 Neurogenic bladder dysfunction
C2936331 BXGD018106 Sarcoglycanopathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Respiratory Tract Diseases; Nervous System Diseases; Cardiovascular Diseases
C2936719 BXGD018130 Mechanical Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2945759 BXGD018189 aggressive cancer
C2973725 BXGD018205 Pulmonary arterial hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C3160909 BXGD018497 Autoimmune arthritis
C3178766 BXGD018535 Nociceptive Pain Pathological Conditions, Signs and Symptoms
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3249881 BXGD018583 Infection - suppurative Pathological Conditions, Signs and Symptoms; Infections
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3665419 BXGD019285 intracranial glioma Neoplasms; Nervous System Diseases
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C3887499 BXGD019884 Renal cyst Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3887558 BXGD019899 Hemophagocytic Syndrome Hemic and Lymphatic Diseases
C4048158 BXGD021890 Convulsions Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4048329 BXGD021904 Immunosuppression
C4049711 BXGD021949 Lepidic Predominant Adenocarcinoma Neoplasms
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4284013 BXGD022428 Primary cholangiocarcinoma of intrahepatic biliary tract Neoplasms
C4290046 BXGD022507 trachomatis
C4511452 BXGD023002 Sporadic Parkinson disease Nervous System Diseases
C4529962 BXGD023178 Fatty Liver Disease
C4551472 BXGD023303 Hypertrophic obstructive cardiomyopathy Cardiovascular Diseases
C4721532 BXGD023752 Lymphoma, Non-Hodgkin, Familial Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0039684 Berberine Chloride 336.12
BXGC0043055 Palmatine Chloride 352.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein