adisease

Showing entry for Optic Neuropathy

General Disease Information
BXGD Id	BXGD019918
Disease Name	Optic Neuropathy
Disease CUI Id	C3887709
MeSH Codes	C11 C10
Disease Class Name	Eye Diseases; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000478
Human Phenotype Ontology Term	Abnormality of the eye
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O15239	BXGT004139	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	4694	reviewed
O60313	BXGT004871	Dynamin-like 120 kDa protein, mitochondrial	4976	reviewed	Enzyme modulator
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P03905	BXGT006113	NADH-ubiquinone oxidoreductase chain 4	4538	reviewed	Enzyme
P03923	BXGT006115	NADH-ubiquinone oxidoreductase chain 6	4541	reviewed
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P06401	BXGT006436	Progesterone receptor	5241	reviewed	Nuclear receptor
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P15121	BXGT008083	Aldo-keto reductase family 1 member B1	231	reviewed	Enzyme
P16473	BXGT008234	Thyrotropin receptor	7253	reviewed	G-protein coupled receptor
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60891	BXGT011337	Ribose-phosphate pyrophosphokinase 1	5631	reviewed	Kinase
Q00535	BXGT012534	Cyclin-dependent-like kinase 5	1020	reviewed	Kinase
Q01453	BXGT012588	Peripheral myelin protein 22	5376	reviewed	Cellular structure
Q12756	BXGT013261	Kinesin-like protein KIF1A	547	reviewed	Cellular structure
Q15046	BXGT013527	Lysine--tRNA ligase	3735	reviewed	Enzyme
Q15077	BXGT013533	P2Y purinoceptor 6	5031	reviewed	G-protein coupled receptor
Q16555	BXGT013638	Dihydropyrimidinase-related protein 2	1808	reviewed	Enzyme
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q8WWV3	BXGT019005	Reticulon-4-interacting protein 1, mitochondrial	84816	reviewed
Q93009	BXGT019455	Ubiquitin carboxyl-terminal hydrolase 7	7874	reviewed	Enzyme
Q99798	BXGT019962	Aconitate hydratase, mitochondrial	50	reviewed	Enzyme
Q99972	BXGT019979	Myocilin	4653	reviewed	Cellular structure
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9P0J0	BXGT021287	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	51079	reviewed	Enzyme
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme
Q04837	BXGT025484	Single-stranded DNA-binding protein, mitochondrial	6742	reviewed	Nucleic acid binding

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}