adisease

Showing entry for High grade glioma

General Disease Information
BXGD Id	BXGD023789
Disease Name	High grade glioma
Disease CUI Id	C4722099
MeSH Codes	C04
Disease Class Name	Neoplasms
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00194	BXGT003892	Ras-related protein Rab-27B	5874	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O14980	BXGT004119	Exportin-1	7514	reviewed	Receptor
O15054	BXGT004121	Lysine-specific demethylase 6B	23135	reviewed	Epigenetic regulator
O43521	BXGT004598	Bcl-2-like protein 11	10018	reviewed
O43809	BXGT004627	Cleavage and polyadenylation specificity factor subunit 5	11051	reviewed	Nucleic acid binding
O75475	BXGT005130	PC4 and SFRS1-interacting protein	11168	reviewed	Signaling
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	3417	reviewed
O95931	BXGT005407	Chromobox protein homolog 7	23492	reviewed	Epigenetic regulator
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01574	BXGT005768	Interferon beta	3456	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04629	BXGT006239	High affinity nerve growth factor receptor	4914	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06753	BXGT006498	Tropomyosin alpha-3 chain	7170	reviewed	Cellular structure
P07355	BXGT006609	Annexin A2	302	reviewed
P08138	BXGT006729	Tumor necrosis factor receptor superfamily member 16	4804	reviewed	Receptor
P08581	BXGT006794	Hepatocyte growth factor receptor	4233	reviewed	Kinase
P08922	BXGT006843	Proto-oncogene tyrosine-protein kinase ROS	6098	reviewed	Kinase
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09936	BXGT006943	Ubiquitin carboxyl-terminal hydrolase isozyme L1	7345	reviewed	Enzyme
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P14784	BXGT008054	Interleukin-2 receptor subunit beta	3560	reviewed	Receptor
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P16234	BXGT008209	Platelet-derived growth factor receptor alpha	5156	reviewed	Kinase
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P18146	BXGT008384	Early growth response protein 1	1958	reviewed	Nucleic acid binding
P22083	BXGT008727	Alpha-(1,3)-fucosyltransferase 4	2526	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P25963	BXGT009080	NF-kappa-B inhibitor alpha	4792	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P30086	BXGT009400	Phosphatidylethanolamine-binding protein 1	5037	reviewed	Enzyme modulator
P30291	BXGT009417	Wee1-like protein kinase	7465	reviewed	Kinase
P30536	BXGT009435	Translocator protein	706	reviewed
P30988	BXGT009491	Calcitonin receptor	799	reviewed	G-protein coupled receptor
P31260	BXGT009519	Homeobox protein Hox-A10	3206	reviewed
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P31751	BXGT009576	RAC-beta serine/threonine-protein kinase	208	reviewed	Kinase
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P36955	BXGT009946	Pigment epithelium-derived factor	5176	reviewed	Enzyme modulator
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41182	BXGT010231	B-cell lymphoma 6 protein	604	reviewed
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P47895	BXGT010593	Aldehyde dehydrogenase family 1 member A3	220	reviewed	Enzyme
P48735	BXGT010657	Isocitrate dehydrogenase [NADP], mitochondrial	3418	reviewed
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49023	BXGT010672	Paxillin	5829	reviewed	Cellular structure
P50613	BXGT010815	Cyclin-dependent kinase 7	1022	reviewed	Kinase
P55085	BXGT011104	Proteinase-activated receptor 2	2150	reviewed	G-protein coupled receptor
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P61088	BXGT011358	Ubiquitin-conjugating enzyme E2 N	7334	reviewed
P61587	BXGT011376	Rho-related GTP-binding protein RhoE	390	reviewed	Enzyme modulator
P62834	BXGT011464	Ras-related protein Rap-1A	5906	reviewed	Enzyme modulator
P84243	BXGT012052	Histone H3.3	3021	reviewed
Q01094	BXGT012568	Transcription factor E2F1	1869	reviewed	Nucleic acid binding
Q02241	BXGT012644	Kinesin-like protein KIF23	9493	reviewed	Cellular structure
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q04771	BXGT012783	Activin receptor type-1	90	reviewed	Kinase
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q08050	BXGT012958	Forkhead box protein M1	2305	reviewed
Q08493	BXGT012987	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	5143	reviewed
Q14680	BXGT013499	Maternal embryonic leucine zipper kinase	9833	reviewed	Kinase
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q15582	BXGT013581	Transforming growth factor-beta-induced protein ig-h3	7045	reviewed	Signaling
Q15831	BXGT013604	Serine/threonine-protein kinase STK11	6794	reviewed	Kinase
Q16288	BXGT013625	NT-3 growth factor receptor	4916	reviewed	Kinase
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q6ZQY3	BXGT016636	Acidic amino acid decarboxylase GADL1	339896	reviewed
Q92945	BXGT019397	Far upstream element-binding protein 2	8570	reviewed	Enzyme
Q96A70	BXGT019615	Antizyme inhibitor 2	113451	reviewed	Enzyme
Q99814	BXGT019965	Endothelial PAS domain-containing protein 1	2034	reviewed	Transcription factor
Q9HD26	BXGT020540	Golgi-associated PDZ and coiled-coil motif-containing protein	57120	reviewed
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UJ41	BXGT021723	Rab5 GDP/GTP exchange factor	27342	reviewed	Enzyme modulator
Q9UM47	BXGT021772	Neurogenic locus notch homolog protein 3	4854	reviewed
Q9Y243	BXGT022214	RAC-gamma serine/threonine-protein kinase	10000	reviewed	Kinase
Q9Y286	BXGT022225	Sialic acid-binding Ig-like lectin 7	27036	reviewed	Receptor
P16284	BXGT022972	Platelet endothelial cell adhesion molecule	5175	reviewed	Cell adhesion
Q16763	BXGT025332	Ubiquitin-conjugating enzyme E2 S	27338	reviewed
Q9GZV5	BXGT025439	WW domain-containing transcription regulator protein 1	25937	reviewed	Enzyme modulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}