Showing entry for cAMP-specific 3',5'-cyclic phosphodiesterase 4C


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012987
Protein NamecAMP-specific 3',5'-cyclic phosphodiesterase 4C
Uniport IdQ08493
GenePDE4C
Gene Id5143
DomainPDE4_UCR; PDEase_I
Pfam PF18100   PF00233  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00230 Purine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
3. Environmental Information Processing 3.2 Signal transduction hsa04024 cAMP signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action
6. Human Diseases 6.5 Substance dependence hsa05032 Morphine addiction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006198 cAMP catabolic process
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
molecular function GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
molecular function GO:0046872 metal ion binding
cellular component GO:0005929 cilium
cellular component GO:0005829 cytosol
cellular component GO:0005615 extracellular space
Reactome
Pathway Id Pathway Name
R-HSA-111885 Opioid Signalling
R-HSA-162582 Signal Transduction
R-HSA-180024 DARPP-32 events
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-418555 G alpha (s) signalling events
R-HSA-418594 G alpha (i) signalling events
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001430 BXGD000054 Adenoma Neoplasms
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0017638 BXGD001132 Glioma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0202239 BXGD004087 Uric acid measurement (procedure)
C0555198 BXGD009432 Malignant Glioma Neoplasms
C1997217 BXGD016859 Low grade glioma Neoplasms
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4722099 BXGD023789 High grade glioma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000202 Papaverine 339.39
BXGC0000204 Theophylline 180.16
BXGC0000988 3' 5'-cyclic AMP 329.21
BXGC0001502 Caffeine 194.19
BXGC0002588 Magnesium 24.31
BXGC0003776 Flavones 222.24
BXGC0006306 Myricetin 318.24
BXGC0009047 3-Methoxynobiletin 432.42
BXGC0029695 Tocladesine 363.01
BXGC0034941 Combretastatin A4 316.13
BXGC0038499 Xanthine 152.03
BXGC0043908 3-Methylxanthine 166.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein