Showing entry for Fructose-bisphosphate aldolase A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006145
Protein NameFructose-bisphosphate aldolase A
Uniport IdP04075
GeneALDOA
Gene Id226
DomainGlycolytic
Pfam PF00274  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00010 Glycolysis / Gluconeogenesis
1. Metabolism 1.1 Carbohydrate metabolism hsa00030 Pentose phosphate pathway
1. Metabolism 1.1 Carbohydrate metabolism hsa00051 Fructose and mannose metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
1. Metabolism 1.0 Global and overview maps hsa01200 Carbon metabolism
1. Metabolism 1.0 Global and overview maps hsa01230 Biosynthesis of amino acids
3. Environmental Information Processing 3.2 Signal transduction hsa04066 HIF-1 signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007015 actin filament organization
Biological Process GO:0006754 ATP biosynthetic process
Biological Process GO:0007339 binding of sperm to zona pellucida
Biological Process GO:0061621 canonical glycolysis
Biological Process GO:0030388 fructose 1,6-bisphosphate metabolic process
Biological Process GO:0006000 fructose metabolic process
Biological Process GO:0006094 gluconeogenesis
Biological Process GO:0006096 glycolytic process
Biological Process GO:0046716 muscle cell cellular homeostasis
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0002576 platelet degranulation
Biological Process GO:0051289 protein homotetramerization
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0006941 striated muscle contraction
molecular function GO:0003779 actin binding
molecular function GO:0045296 cadherin binding
molecular function GO:0008092 cytoskeletal protein binding
molecular function GO:0070061 fructose binding
molecular function GO:0004332 fructose-bisphosphate aldolase activity
molecular function GO:0042802 identical protein binding
molecular function GO:0003723 RNA binding
molecular function GO:0015631 tubulin binding
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:1904813 ficolin-1-rich granule lumen
cellular component GO:0031674 I band
cellular component GO:0031430 M band
cellular component GO:0016020 membrane
cellular component GO:0005634 nucleus
cellular component GO:0031093 platelet alpha granule lumen
cellular component GO:0034774 secretory granule lumen
cellular component GO:0061827 sperm head
cellular component GO:1904724 tertiary granule lumen
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-114608 Platelet degranulation
R-HSA-1430728 Metabolism
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-6798695 Neutrophil degranulation
R-HSA-70171 Glycolysis
R-HSA-70263 Gluconeogenesis
R-HSA-70326 Glucose metabolism
R-HSA-71387 Metabolism of carbohydrates
R-HSA-76002 Platelet activation, signaling and aggregation
R-HSA-76005 Response to elevated platelet cytosolic Ca2+
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002878 BXGD000137 Anemia, Hemolytic Hemic and Lymphatic Diseases
C0002881 BXGD000140 Anemia, Hemolytic, Congenital Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0005745 BXGD000331 Blepharoptosis Eye Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0008325 BXGD000529 Cholecystitis Digestive System Diseases
C0008350 BXGD000531 Cholelithiasis Digestive System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0017919 BXGD001150 Glycogen Storage Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0022346 BXGD001537 Icterus Pathological Conditions, Signs and Symptoms
C0023885 BXGD001711 Liver Abscess Digestive System Diseases; Infections
C0027626 BXGD002005 Neoplasm Invasiveness Pathological Conditions, Signs and Symptoms; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0033377 BXGD002406 Ptosis Pathological Conditions, Signs and Symptoms
C0034012 BXGD002449 Delayed Puberty Endocrine System Diseases
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0085577 BXGD003189 Normocytic anemia Hemic and Lymphatic Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0235983 BXGD004798 Normochromic anemia Hemic and Lymphatic Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0271055 BXGD006154 Rhegmatogenous retinal detachment Eye Diseases
C0272066 BXGD006299 Glycogen Storage Disease XII Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349588 BXGD007933 Short stature
C0376618 BXGD008003 Endotoxemia Pathological Conditions, Signs and Symptoms; Infections
C0520572 BXGD009093 Enzymopathy Nutritional and Metabolic Diseases
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0521525 BXGD009139 Short neck
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0678230 BXGD009750 Congenital Epicanthus
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0740277 BXGD009972 Bile duct carcinoma Digestive System Diseases; Neoplasms
C0949690 BXGD011584 Spondylarthritis Musculoskeletal Diseases
C0949691 BXGD011585 Spondylarthropathies Musculoskeletal Diseases
C1176475 BXGD011798 Ductal Carcinoma Neoplasms
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1527349 BXGD013277 Ductal Breast Carcinoma Neoplasms
C1855728 BXGD015536 Low posterior hairline
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2919142 BXGD017867 Short Stature, CTCAE
C2931852 BXGD018079 Clear-cell metastatic renal cell carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4025735 BXGD021767 Nonspherocytic hemolytic anemia Hemic and Lymphatic Diseases
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001096 Dihydroxyacetone phosphate 170.06
BXGC0002682 Zinc 65.41
BXGC0051100 dihydroartemisinin 284.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein