Showing entry for Ductal Breast Carcinoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD013277
Disease NameDuctal Breast Carcinoma
Disease CUI IdC1527349
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O43255 BXGT004579 E3 ubiquitin-protein ligase SIAH2 6478 reviewed
O60566 BXGT004884 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta 701 reviewed Kinase
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01574 BXGT005768 Interferon beta 3456 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02795 BXGT005968 Metallothionein-2 4502 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04075 BXGT006145 Fructose-bisphosphate aldolase A 226 reviewed
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07355 BXGT006609 Annexin A2 302 reviewed
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08151 BXGT006731 Zinc finger protein GLI1 2735 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08670 BXGT006810 Vimentin 7431 reviewed
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10619 BXGT007589 Lysosomal protective protein 5476 reviewed Enzyme
P11308 BXGT007684 Transcriptional regulator ERG 2078 reviewed Transcription factor
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12830 BXGT007852 Cadherin-1 999 reviewed
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src 6714 reviewed Kinase
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P15498 BXGT008133 Proto-oncogene vav 7409 reviewed
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15927 BXGT008174 Replication protein A 32 kDa subunit 6118 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16220 BXGT008206 Cyclic AMP-responsive element-binding protein 1 1385 reviewed
P16581 BXGT008245 E-selectin 6401 reviewed
P17735 BXGT008335 Tyrosine aminotransferase 6898 reviewed
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P20936 BXGT008619 Ras GTPase-activating protein 1 5921 reviewed Enzyme modulator
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25311 BXGT009036 Zinc-alpha-2-glycoprotein 563 reviewed
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30101 BXGT009402 Protein disulfide-isomerase A3 2923 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35442 BXGT009832 Thrombospondin-2 7058 reviewed
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 6197 reviewed Kinase
P52701 BXGT010943 DNA mismatch repair protein Msh6 2956 reviewed Nucleic acid binding
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 5563 reviewed Kinase
P55212 BXGT011112 Caspase-6 839 reviewed Enzyme
P56937 BXGT011205 3-keto-steroid reductase 51478 reviewed
P56945 BXGT011206 Breast cancer anti-estrogen resistance protein 1 9564 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
P63279 BXGT011514 SUMO-conjugating enzyme UBC9 7329 reviewed
P68104 BXGT011575 Elongation factor 1-alpha 1 1915 reviewed Enzyme
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q04724 BXGT012778 Transducin-like enhancer protein 1 7088 reviewed Transcription factor
Q05397 BXGT012815 Focal adhesion kinase 1 5747 reviewed Kinase
Q05513 BXGT012820 Protein kinase C zeta type 5590 reviewed Kinase
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform 5530 reviewed
Q09328 BXGT013034 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A 4249 reviewed Enzyme
Q12797 BXGT013266 Aspartyl/asparaginyl beta-hydroxylase 444 reviewed
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 5562 reviewed Kinase
Q13257 BXGT013333 Mitotic spindle assembly checkpoint protein MAD2A 4085 reviewed
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q15084 BXGT013536 Protein disulfide-isomerase A6 10130 reviewed
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16637 BXGT013646 Survival motor neuron protein 6607 reviewed Epigenetic regulator
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16853 BXGT013683 Membrane primary amine oxidase 8639 reviewed
Q53EL6 BXGT015008 Programmed cell death protein 4 27250 reviewed Nucleic acid binding
Q8WXF7 BXGT019011 Atlastin-1 51062 reviewed Enzyme modulator
Q92547 BXGT019355 DNA topoisomerase 2-binding protein 1 11073 reviewed
Q92698 BXGT019362 DNA repair and recombination protein RAD54-like 8438 reviewed
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q969G3 BXGT019607 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 6605 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q99519 BXGT019928 Sialidase-1 4758 reviewed Enzyme
Q99685 BXGT019948 Monoglyceride lipase 11343 reviewed Enzyme
Q9BUB5 BXGT020133 MAP kinase-interacting serine/threonine-protein kinase 1 8569 reviewed Kinase
Q9H0P0 BXGT020439 Cytosolic 5'-nucleotidase 3A 51251 reviewed Enzyme
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9UGL1 BXGT021685 Lysine-specific demethylase 5B 10765 reviewed Epigenetic regulator
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9Y2J8 BXGT022237 Protein-arginine deiminase type-2 11240 reviewed
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 5564 reviewed Kinase
P35240 BXGT022927 Merlin 4771 reviewed
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease