Showing entry for Gag-Pol polyprotein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006234
Protein NameGag-Pol polyprotein
Uniport IdP04585
Genegag-pol
Gene Id155348
DomainGag_p17; Gag_p24; Integrase_Zn; IN_DBD_C; RNase_H; rve; RVP; RVT_1; RVT_connect; RVT_thumb; zf-CCHC
Pfam PF00540   PF00607   PF00552   PF02022   PF00075   PF00665   PF00077   PF00078   PF06815   PF06817   PF00098  
OrganismHuman immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006310 DNA recombination
Biological Process GO:0075713 establishment of integrated proviral latency
Biological Process GO:0019064 fusion of virus membrane with host plasma membrane
Biological Process GO:0039651 induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0051169 nuclear transport
Biological Process GO:0006278 RNA-dependent DNA biosynthetic process
Biological Process GO:0039657 suppression by virus of host gene expression
Biological Process GO:0019061 uncoating of virus
Biological Process GO:0044826 viral genome integration into host DNA
Biological Process GO:0019072 viral genome packaging
Biological Process GO:0019058 viral life cycle
Biological Process GO:0075732 viral penetration into host nucleus
Biological Process GO:0019068 virion assembly
molecular function GO:0004190 aspartic-type endopeptidase activity
molecular function GO:0003677 DNA binding
molecular function GO:0003887 DNA-directed DNA polymerase activity
molecular function GO:0004533 exoribonuclease H activity
molecular function GO:0042802 identical protein binding
molecular function GO:0008907 integrase activity
molecular function GO:0008289 lipid binding
molecular function GO:0008233 peptidase activity
molecular function GO:0003723 RNA binding
molecular function GO:0003964 RNA-directed DNA polymerase activity
molecular function GO:0004523 RNA-DNA hybrid ribonuclease activity
molecular function GO:0005198 structural molecule activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0042025 host cell nucleus
cellular component GO:0020002 host cell plasma membrane
cellular component GO:0072494 host multivesicular body
cellular component GO:0019013 viral nucleocapsid
cellular component GO:0055036 virion membrane
Reactome
Pathway Id Pathway Name
R-HSA-162585 Uncoating of the HIV Virion
R-HSA-162587 HIV Life Cycle
R-HSA-162588 Budding and maturation of HIV virion
R-HSA-162589 Reverse Transcription of HIV RNA
R-HSA-162592 Integration of provirus
R-HSA-162594 Early Phase of HIV Life Cycle
R-HSA-162599 Late Phase of HIV Life Cycle
R-HSA-162906 HIV Infection
R-HSA-162909 Host Interactions of HIV factors
R-HSA-1643685 Disease
R-HSA-164516 Minus-strand DNA synthesis
R-HSA-164525 Plus-strand DNA synthesis
R-HSA-164843 2-LTR circle formation
R-HSA-173107 Binding and entry of HIV virion
R-HSA-175474 Assembly Of The HIV Virion
R-HSA-175567 Integration of viral DNA into host genomic DNA
R-HSA-176033 Interactions of Vpr with host cellular proteins
R-HSA-177539 Autointegration results in viral DNA circles
R-HSA-180689 APOBEC3G mediated resistance to HIV-1 infection
R-HSA-180910 Vpr-mediated nuclear import of PICs
R-HSA-5663205 Infectious disease
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000076 p-Coumaroyl tartaric acid glucosidic ester 150.09
BXGC0000436 Glycerol 92.09
BXGC0001857 Caffeic acid 180.16
BXGC0002018 Morin 302.24
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0002591 Potassium 39.1
BXGC0002675 Sugars 342.3
BXGC0002791 Methylamine 31.06
BXGC0003705 Chloride 35.45
BXGC0004188 Propanedioic acid 104.06
BXGC0005682 3,3',4,4'-Tetrahydroxylignan 302.36
BXGC0006162 L-Glutamic acid 147.13
BXGC0006368 Formic acid 46.03
BXGC0013084 Kuwanon L 626.18
BXGC0015288 mesotartaric acid 150.02
BXGC0020344 Icosa-5,8,11,14-Tetraynoic Acid 296.18
BXGC0024810 curcumin 368.13
BXGC0039397 Athraquinones A 240.04
BXGC0045255 R 82913 321.11
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein