Showing entry for Muscarinic acetylcholine receptor M2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007641
Protein NameMuscarinic acetylcholine receptor M2
Uniport IdP10980
GeneChrm2
Gene Id81645
Domain7tm_1
Pfam PF00001  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007197 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0007213 G protein-coupled acetylcholine receptor signaling pathway
Biological Process GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
Biological Process GO:0008016 regulation of heart contraction
Biological Process GO:0006940 regulation of smooth muscle contraction
Biological Process GO:2000300 regulation of synaptic vesicle exocytosis
Biological Process GO:0009615 response to virus
molecular function GO:1990763 arrestin family protein binding
molecular function GO:0016907 G protein-coupled acetylcholine receptor activity
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0004993 G protein-coupled serotonin receptor activity
molecular function GO:0030594 neurotransmitter receptor activity
cellular component GO:0032279 asymmetric synapse
cellular component GO:0043679 axon terminus
cellular component GO:0098981 cholinergic synapse
cellular component GO:0030425 dendrite
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099055 integral component of postsynaptic membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0016020 membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0005886 plasma membrane
cellular component GO:0032280 symmetric synapse
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001589 Arecoline 155.19
BXGC0002796 Nicotine 162.23
BXGC0002852 Atropine 289.37
BXGC0003102 Acetylcholine 146.21
BXGC0014455 Fanchinin 622.3
BXGC0030685 Physostigmine 275.16
BXGC0031080 Scopolamine 303.15
BXGC0035865 (+)-Pentazocine 285.21
BXGC0039319 Muscarine 174.15
BXGC0042114 Solifenacin 362.2
BXGC0042179 Atropine 289.17
BXGC0042510 Fluoxetine 309.13
BXGC0046737 Berbamine 608.29
BXGC0046755 Yohimbine 354.19
BXGC0048924 homatropine 275.15
BXGC0051660 Endo-Atropine 289.17
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein