Showing entry for Kallistatin


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009370
Protein NameKallistatin
Uniport IdP29622
GeneSERPINA4
Gene Id5267
DomainSerpin
Pfam PF00079  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0010951 negative regulation of endopeptidase activity
Biological Process GO:0002576 platelet degranulation
molecular function GO:0004867 serine-type endopeptidase inhibitor activity
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0031089 platelet dense granule lumen
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-114608 Platelet degranulation
R-HSA-76002 Platelet activation, signaling and aggregation
R-HSA-76005 Response to elevated platelet cytosolic Ca2+
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0004936 BXGD000295 Mental disorders Mental Disorders
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0014356 BXGD000910 Enterocolitis Digestive System Diseases
C0019243 BXGD001308 Angioedemas, Hereditary Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases; Cardiovascular Diseases
C0020619 BXGD001447 Hypogonadism Endocrine System Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022735 BXGD001581 Klinefelter Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0025362 BXGD001866 Mental Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0042580 BXGD002992 Vesico-Ureteral Reflux Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0162809 BXGD003981 Kallmann Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0220766 BXGD004341 Congenital hypoplasia of adrenal gland Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases
C0238210 BXGD004895 Malrotation of kidney
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0266294 BXGD005644 Unilateral agenesis of kidney Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0271623 BXGD006222 Hypogonadotropic hypogonadism Endocrine System Diseases
C0342384 BXGD007470 Idiopathic hypogonadotropic hypogonadism Endocrine System Diseases
C0342482 BXGD007486 X-linked Adrenal Hypoplasia Endocrine System Diseases
C0345967 BXGD007756 Malignant mesothelioma Neoplasms; Respiratory Tract Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0542519 BXGD009279 Congenital absence of kidney Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0549463 BXGD009382 X-Linked Lymphoproliferative Disorder Immune System Diseases; Hemic and Lymphatic Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510460 BXGD013168 Orofaciodigital Syndrome I Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1619700 BXGD013459 RENAL ADYSPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1720275 BXGD013670 Gonadotropin releasing factor deficiency Nervous System Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2931498 BXGD018030 Mental Retardation, X-Linked 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C2945695 BXGD018187 Limb ischemia
C2985280 BXGD018223 Blood Protein Measurement
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002616 Copper 63.55
BXGC0002682 Zinc 65.41
BXGC0003705 Chloride 35.45
BXGC0018397 beta-1,4-mannan 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein