Showing entry for Vesico-Ureteral Reflux


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002992
Disease NameVesico-Ureteral Reflux
Disease CUI IdC0042580
MeSH Codes C13   C12  
Disease Class NameFemale Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000119  
Human Phenotype Ontology TermAbnormality of the genitourinary system
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00571 BXGT003938 ATP-dependent RNA helicase DDX3X 1654 reviewed
O14578 BXGT004072 Citron Rho-interacting kinase 11113 reviewed Kinase
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15553 BXGT004181 Pyrin 4210 reviewed
O43318 BXGT004586 Mitogen-activated protein kinase kinase kinase 7 6885 reviewed Kinase
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O76039 BXGT005171 Cyclin-dependent kinase-like 5 6792 reviewed Kinase
O94813 BXGT005337 Slit homolog 2 protein 9353 reviewed
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P02462 BXGT005881 Collagen alpha-1(IV) chain 1282 reviewed
P02760 BXGT005948 Protein AMBP 259 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P06870 BXGT006518 Kallikrein-1 3816 reviewed Enzyme
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10826 BXGT007622 Retinoic acid receptor beta 5915 reviewed Nuclear receptor
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13224 BXGT007890 Platelet glycoprotein Ib beta chain 2812 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 1131 reviewed G-protein coupled receptor
P21333 BXGT008638 Filamin-A 2316 reviewed
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P25024 BXGT009005 C-X-C chemokine receptor type 1 3577 reviewed G-protein coupled receptor
P29622 BXGT009370 Kallistatin 5267 reviewed Enzyme modulator
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P31040 BXGT009503 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 6389 reviewed Enzyme
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P46100 BXGT010508 Transcriptional regulator ATRX 546 reviewed
P50052 BXGT010768 Type-2 angiotensin II receptor 186 reviewed G-protein coupled receptor
P51787 BXGT010889 Potassium voltage-gated channel subfamily KQT member 1 3784 reviewed Ion channel
P53667 BXGT011008 LIM domain kinase 1 3984 reviewed Kinase
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform 5530 reviewed
Q12830 BXGT013268 Nucleosome-remodeling factor subunit BPTF 2186 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14683 BXGT013500 Structural maintenance of chromosomes protein 1A 8243 reviewed
Q14839 BXGT013509 Chromodomain-helicase-DNA-binding protein 4 1108 reviewed
Q15652 BXGT013587 Probable JmjC domain-containing histone demethylation protein 2C 221037 reviewed
Q17RS7 BXGT013697 Flap endonuclease GEN homolog 1 348654 reviewed
Q6XUX3 BXGT016612 Dual serine/threonine and tyrosine protein kinase 25778 reviewed Kinase
Q7Z3B3 BXGT017249 KAT8 regulatory NSL complex subunit 1 284058 reviewed
Q86WV6 BXGT017626 Stimulator of interferon genes protein 340061 reviewed
Q8NEM0 BXGT018555 Microcephalin 79648 reviewed Nucleic acid binding
Q8NFD5 BXGT018560 AT-rich interactive domain-containing protein 1B 57492 reviewed
Q8NG31 BXGT018565 Kinetochore scaffold 1 57082 reviewed
Q93009 BXGT019455 Ubiquitin carboxyl-terminal hydrolase 7 7874 reviewed Enzyme
Q96C36 BXGT019631 Pyrroline-5-carboxylate reductase 2 29920 reviewed
Q9BY41 BXGT020180 Histone deacetylase 8 55869 reviewed Epigenetic regulator
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9H4W6 BXGT020478 Transcription factor COE3 253738 reviewed
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9NRF2 BXGT021185 SH2B adapter protein 1 25970 reviewed
Q9NSD9 BXGT021206 Phenylalanine--tRNA ligase beta subunit 10056 reviewed Enzyme
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9UHX1 BXGT021707 Poly(U)-binding-splicing factor PUF60 22827 reviewed
Q9HCK4 BXGT024280 Roundabout homolog 2 6092 reviewed
Q96L73 BXGT024676 Histone-lysine N-methyltransferase, H3 lysine-36 specific 64324 reviewed Epigenetic regulator
P35250 BXGT025854 Replication factor C subunit 2 5982 reviewed Enzyme
Q9UQE7 BXGT025899 Structural maintenance of chromosomes protein 3 9126 reviewed
Q6UVJ0 BXGT026024 Spindle assembly abnormal protein 6 homolog 163786 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease