Showing entry for UMP-CMP kinase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009399
Protein NameUMP-CMP kinase
Uniport IdP30085
GeneCMPK1
Gene Id51727
DomainADK
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00240 Pyrimidine metabolism
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
Biological Process GO:0046705 CDP biosynthetic process
Biological Process GO:0015949 nucleobase-containing small molecule interconversion
Biological Process GO:0006165 nucleoside diphosphate phosphorylation
Biological Process GO:0009142 nucleoside triphosphate biosynthetic process
Biological Process GO:0006163 purine nucleotide metabolic process
Biological Process GO:0009220 pyrimidine ribonucleotide biosynthetic process
Biological Process GO:0006225 UDP biosynthetic process
molecular function GO:0005524 ATP binding
molecular function GO:0004127 cytidylate kinase activity
molecular function GO:0004550 nucleoside diphosphate kinase activity
molecular function GO:0033862 UMP kinase activity
molecular function GO:0004849 uridine kinase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-15869 Metabolism of nucleotides
R-HSA-499943 Interconversion of nucleotide di- and triphosphates
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009946 BXGD000638 Conversion disorder Mental Disorders
C0017638 BXGD001132 Glioma Neoplasms
C0018482 BXGD001194 Haemophilus Infections Infections
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0021364 BXGD001500 Male infertility Male Urogenital Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023440 BXGD001646 Acute Erythroblastic Leukemia Neoplasms; Hemic and Lymphatic Diseases
C0023462 BXGD001654 Acute Megakaryocytic Leukemias Neoplasms
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0035243 BXGD002522 Respiratory Tract Infections Infections; Respiratory Tract Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0042769 BXGD002999 Virus Diseases Infections
C0043154 BXGD003033 Dental White Spot Stomatognathic Diseases
C0206368 BXGD004176 Exfoliation Syndrome Eye Diseases
C0206708 BXGD004256 Cervical Intraepithelial Neoplasia Neoplasms
C0220620 BXGD004299 Gastrointestinal Carcinoid Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0524909 BXGD009247 Hepatitis B, Chronic Digestive System Diseases; Infections
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1318881 BXGD012406 Vancomycin intermediate staphylococcus aureus infection
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C2028293 BXGD016885 Haemophilus influenzae Type b Infection Infections
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4528668 BXGD023176 Acute myeloid leukaemia refractory Neoplasms
C4551720 BXGD023400 Primary Ciliary Dyskinesia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003418 Undylic acid 324.18
BXGC0003993 Uridine diphosphate 404.16
BXGC0025560 Deoxycytidine Monophosphate 307.06
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein