Showing entry for Hepatitis B, Chronic


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD009247
Disease NameHepatitis B, Chronic
Disease CUI IdC0524909
MeSH Codes C06   C01  
Disease Class NameDigestive System Diseases; Infections
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00182 BXGT003889 Galectin-9 3965 reviewed Signaling
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00337 BXGT003911 Sodium/nucleoside cotransporter 1 9154 reviewed Transporter
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O75015 BXGT005095 Low affinity immunoglobulin gamma Fc region receptor III-B 2215 reviewed Cell adhesion
O75084 BXGT005098 Frizzled-7 8324 reviewed G-protein coupled receptor
O75914 BXGT005165 Serine/threonine-protein kinase PAK 3 5063 reviewed Kinase
O95255 BXGT005363 Multidrug resistance-associated protein 6 368 reviewed Transporter
O95407 BXGT005380 Tumor necrosis factor receptor superfamily member 6B 8771 reviewed
O95786 BXGT005396 Probable ATP-dependent RNA helicase DDX58 23586 reviewed
P00325 BXGT005498 Alcohol dehydrogenase 1B 125 reviewed Enzyme
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00751 BXGT005643 Complement factor B 629 reviewed
P01008 BXGT005713 Antithrombin-III 462 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01574 BXGT005768 Interferon beta 3456 reviewed
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P01920 BXGT005817 HLA class II histocompatibility antigen, DQ beta 1 chain 3119 reviewed Immune response
P02461 BXGT005880 Collagen alpha-1(III) chain 1281 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02656 BXGT005913 Apolipoprotein C-III 345 reviewed
P02730 BXGT005935 Band 3 anion transport protein 6521 reviewed Transporter
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02748 BXGT005940 Complement component C9 735 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05161 BXGT006331 Ubiquitin-like protein ISG15 9636 reviewed Nucleic acid binding
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05787 BXGT006385 Keratin, type II cytoskeletal 8 3856 reviewed
P06396 BXGT006435 Gelsolin 2934 reviewed Cellular structure
P06681 BXGT006468 Complement C2 717 reviewed
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P08686 BXGT006813 Steroid 21-hydroxylase 1589 reviewed
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P10144 BXGT007541 Granzyme B 3002 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P12319 BXGT007800 High affinity immunoglobulin epsilon receptor subunit alpha 2205 reviewed Cell adhesion
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P12830 BXGT007852 Cadherin-1 999 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14555 BXGT008020 Phospholipase A2, membrane associated 5320 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15813 BXGT008158 Antigen-presenting glycoprotein CD1d 912 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16581 BXGT008245 E-selectin 6401 reviewed
P16871 BXGT008269 Interleukin-7 receptor subunit alpha 3575 reviewed Receptor
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19440 BXGT008481 Glutathione hydrolase 1 proenzyme 2678 reviewed Enzyme
P21266 BXGT008632 Glutathione S-transferase Mu 3 2947 reviewed
P21439 BXGT008649 Phosphatidylcholine translocator ABCB4 5244 reviewed Transporter
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21817 BXGT008693 Ryanodine receptor 1 6261 reviewed Ion channel
P22087 BXGT008729 rRNA 2'-O-methyltransferase fibrillarin 2091 reviewed Enzyme
P23588 BXGT008887 Eukaryotic translation initiation factor 4B 1975 reviewed Nucleic acid binding
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P25963 BXGT009080 NF-kappa-B inhibitor alpha 4792 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27352 BXGT009174 Cobalamin binding intrinsic factor 2694 reviewed
P27707 BXGT009201 Deoxycytidine kinase 1633 reviewed Kinase
P28161 BXGT009234 Glutathione S-transferase Mu 2 2946 reviewed
P30085 BXGT009399 UMP-CMP kinase 51727 reviewed Kinase
P31260 BXGT009519 Homeobox protein Hox-A10 3206 reviewed
P32302 BXGT009619 C-X-C chemokine receptor type 5 643 reviewed G-protein coupled receptor
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P33681 BXGT009739 T-lymphocyte activation antigen CD80 941 reviewed
P34931 BXGT009771 Heat shock 70 kDa protein 1-like 3305 reviewed
P34972 BXGT009779 Cannabinoid receptor 2 1269 reviewed G-protein coupled receptor
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38571 BXGT010054 Lysosomal acid lipase/cholesteryl ester hydrolase 3988 reviewed Enzyme
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P40933 BXGT010209 Interleukin-15 3600 reviewed
P41273 BXGT010251 Tumor necrosis factor ligand superfamily member 9 8744 reviewed
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P43403 BXGT010385 Tyrosine-protein kinase ZAP-70 7535 reviewed Kinase
P43490 BXGT010395 Nicotinamide phosphoribosyltransferase 10135 reviewed Signaling
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P48551 BXGT010645 Interferon alpha/beta receptor 2 3455 reviewed Receptor
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P55087 BXGT011105 Aquaporin-4 361 reviewed Ion channel
P55157 BXGT011108 Microsomal triglyceride transfer protein large subunit 4547 reviewed Transporter
P55265 BXGT011117 Double-stranded RNA-specific adenosine deaminase 103 reviewed Enzyme
P56537 BXGT011177 Eukaryotic translation initiation factor 6 3692 reviewed Nucleic acid binding
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60981 BXGT011344 Destrin 11034 reviewed
P62993 BXGT011480 Growth factor receptor-bound protein 2 2885 reviewed
P68036 BXGT011572 Ubiquitin-conjugating enzyme E2 L3 7332 reviewed Enzyme
P78358 BXGT011838 Cancer/testis antigen 1 246100 reviewed
P78536 BXGT011847 Disintegrin and metalloproteinase domain-containing protein 17 6868 reviewed
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P80511 BXGT011914 Protein S100-A12 6283 reviewed Calcium-binding protein
P81172 BXGT011935 Hepcidin 57817 reviewed
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00610 BXGT012539 Clathrin heavy chain 1 1213 reviewed Transporter
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q03518 BXGT012723 Antigen peptide transporter 1 6890 reviewed Transporter
Q04637 BXGT012771 Eukaryotic translation initiation factor 4 gamma 1 1981 reviewed Nucleic acid binding
Q07011 BXGT012912 Tumor necrosis factor receptor superfamily member 9 3604 reviewed
Q07108 BXGT012919 Early activation antigen CD69 969 reviewed
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q08334 BXGT012981 Interleukin-10 receptor subunit beta 3588 reviewed Receptor
Q12918 BXGT013280 Killer cell lectin-like receptor subfamily B member 1 3820 reviewed
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 5562 reviewed Kinase
Q13423 BXGT013352 NAD(P) transhydrogenase, mitochondrial 23530 reviewed Enzyme
Q13478 BXGT013362 Interleukin-18 receptor 1 8809 reviewed Receptor
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 5300 reviewed
Q13546 BXGT013372 Receptor-interacting serine/threonine-protein kinase 1 8737 reviewed Kinase
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14973 BXGT013515 Sodium/bile acid cotransporter 6554 reviewed Transporter
Q15113 BXGT013538 Procollagen C-endopeptidase enhancer 1 5118 reviewed
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q15493 BXGT013575 Regucalcin 9104 reviewed Enzyme
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16666 BXGT013654 Gamma-interferon-inducible protein 16 3428 reviewed Transcription factor
Q16874 BXGT013685 Cytochrome P450 21-hydroxylase 1589 unreviewed
Q16878 BXGT013687 Cysteine dioxygenase type 1 1036 reviewed
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q5VWK5 BXGT015891 Interleukin-23 receptor 149233 reviewed Signaling
Q5Y7D3 BXGT015912 HLA class II histocompatibility antigen DQ beta chain 3119 unreviewed
Q6NYC1 BXGT016436 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 23210 reviewed Receptor
Q6P589 BXGT016452 Tumor necrosis factor alpha-induced protein 8-like protein 2 79626 reviewed
Q6ZMJ4 BXGT016628 Interleukin-34 146433 reviewed
Q7Z434 BXGT017252 Mitochondrial antiviral-signaling protein 57506 reviewed
Q86WV6 BXGT017626 Stimulator of interferon genes protein 340061 reviewed
Q8TD30 BXGT018805 Alanine aminotransferase 2 84706 reviewed Enzyme
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q8TDU6 BXGT018814 G-protein coupled bile acid receptor 1 151306 reviewed G-protein coupled receptor
Q8WY64 BXGT019017 E3 ubiquitin-protein ligase MYLIP 29116 reviewed
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96E93 BXGT019645 Killer cell lectin-like receptor subfamily G member 1 10219 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 10919 reviewed Epigenetic regulator
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96PD4 BXGT019705 Interleukin-17F 112744 reviewed
Q99814 BXGT019965 Endothelial PAS domain-containing protein 1 2034 reviewed Transcription factor
Q9BY64 BXGT020182 UDP-glucuronosyltransferase 2B28 54490 reviewed
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9HAW7 BXGT020508 UDP-glucuronosyltransferase 1-7 54577 reviewed
Q9HBE5 BXGT020518 Interleukin-21 receptor 50615 reviewed Receptor
Q9HC16 BXGT020525 DNA dC->dU-editing enzyme APOBEC-3G 60489 reviewed Enzyme
Q9NNX6 BXGT021140 CD209 antigen 30835 reviewed Receptor
Q9NPH2 BXGT021158 Inositol-3-phosphate synthase 1 51477 reviewed
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NYK1 BXGT021258 Toll-like receptor 7 51284 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UH17 BXGT021691 DNA dC->dU-editing enzyme APOBEC-3B 9582 reviewed Enzyme
Q9UN36 BXGT021780 Protein NDRG2 57447 reviewed Enzyme
Q9Y275 BXGT022223 Tumor necrosis factor ligand superfamily member 13B 10673 reviewed
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y2R2 BXGT022243 Tyrosine-protein phosphatase non-receptor type 22 26191 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q5JP69 BXGT022691 C3/C5 convertase 717 unreviewed
P20036 BXGT022764 HLA class II histocompatibility antigen, DP alpha 1 chain 3113 reviewed Immune response
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q96QC4 BXGT023878 MHC class I polypeptide-related sequence A 100507436 unreviewed
P15260 BXGT023924 Interferon gamma receptor 1 3459 reviewed Receptor
P07954 BXGT023939 Fumarate hydratase, mitochondrial 2271 reviewed Enzyme
P29590 BXGT024350 Protein PML 5371 reviewed
Q7Z6A9 BXGT025024 B- and T-lymphocyte attenuator 151888 reviewed
Q96MS0 BXGT025241 Roundabout homolog 3 64221 reviewed Receptor
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
Q9UKU9 BXGT025985 Angiopoietin-related protein 2 23452 reviewed Signaling
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease