Showing entry for Respiratory Tract Infections


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002522
Disease NameRespiratory Tract Infections
Disease CUI IdC0035243
MeSH Codes C01   C08  
Disease Class NameInfections; Respiratory Tract Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0002086  
Human Phenotype Ontology TermAbnormality of the respiratory system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14920 BXGT004110 Inhibitor of nuclear factor kappa-B kinase subunit beta 3551 reviewed Kinase
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O75636 BXGT005141 Ficolin-3 8547 reviewed Signaling
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O95786 BXGT005396 Probable ATP-dependent RNA helicase DDX58 23586 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00505 BXGT005560 Aspartate aminotransferase, mitochondrial 2806 reviewed
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01574 BXGT005768 Interferon beta 3456 reviewed
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01732 BXGT005782 T-cell surface glycoprotein CD8 alpha chain 925 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02760 BXGT005948 Protein AMBP 259 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06396 BXGT006435 Gelsolin 2934 reviewed Cellular structure
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P0C0L4 BXGT007387 Complement C4-A 721 reviewed
P0C0L5 BXGT007388 Complement C4-B 721 reviewed
P0DMV8 BXGT007509 Heat shock 70 kDa protein 1A 3304 reviewed
P0DMV9 BXGT007510 Heat shock 70 kDa protein 1B 3304 reviewed
P10153 BXGT007544 Non-secretory ribonuclease 6036 reviewed
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P12318 BXGT007799 Low affinity immunoglobulin gamma Fc region receptor II-a 2212 reviewed Cell adhesion
P13236 BXGT007891 C-C motif chemokine 4 6351 reviewed
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P14151 BXGT007990 L-selectin 6402 reviewed
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14616 BXGT008026 Insulin receptor-related protein 3645 reviewed Kinase
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16871 BXGT008269 Interleukin-7 receptor subunit alpha 3575 reviewed Receptor
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P22304 BXGT008752 Iduronate 2-sulfatase 3423 reviewed
P22894 BXGT008815 Neutrophil collagenase 4317 reviewed Enzyme
P25105 BXGT009021 Platelet-activating factor receptor 5724 reviewed G-protein coupled receptor
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P27986 BXGT009216 Phosphatidylinositol 3-kinase regulatory subunit alpha 5295 reviewed Kinase
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P30085 BXGT009399 UMP-CMP kinase 51727 reviewed Kinase
P30874 BXGT009475 Somatostatin receptor type 2 6752 reviewed G-protein coupled receptor
P31639 BXGT009556 Sodium/glucose cotransporter 2 6524 reviewed Transporter
P31785 BXGT009577 Cytokine receptor common subunit gamma 3561 reviewed Signaling
P35247 BXGT009804 Pulmonary surfactant-associated protein D 6441 reviewed Surfactant
P35754 BXGT009863 Glutaredoxin-1 2745 reviewed
P35858 BXGT009876 Insulin-like growth factor-binding protein complex acid labile subunit 3483 reviewed Receptor
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P43403 BXGT010385 Tyrosine-protein kinase ZAP-70 7535 reviewed Kinase
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49591 BXGT010715 Serine--tRNA ligase, cytoplasmic 6301 reviewed Enzyme
P59666 BXGT011273 Neutrophil defensin 3 1668 reviewed
P60022 BXGT011285 Beta-defensin 1 1672 reviewed
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60891 BXGT011337 Ribose-phosphate pyrophosphokinase 1 5631 reviewed Kinase
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P81172 BXGT011935 Hepcidin 57817 reviewed
P98066 BXGT012225 Tumor necrosis factor-inducible gene 6 protein 7130 reviewed
Q01469 BXGT012590 Fatty acid-binding protein 5 2171 reviewed
Q06520 BXGT012880 Bile salt sulfotransferase 6822 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q15485 BXGT013574 Ficolin-2 2220 reviewed Signaling
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16637 BXGT013646 Survival motor neuron protein 6607 reviewed Epigenetic regulator
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q29980 BXGT013981 MHC class I polypeptide-related sequence B 4277 reviewed
Q6PI48 BXGT016471 Aspartate--tRNA ligase, mitochondrial 55157 reviewed Enzyme
Q6QHF9 BXGT016497 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase 196743 reviewed
Q92834 BXGT019381 X-linked retinitis pigmentosa GTPase regulator 6103 reviewed
Q96E93 BXGT019645 Killer cell lectin-like receptor subfamily G member 1 10219 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9H6P5 BXGT020483 Threonine aspartase 1 55617 reviewed Enzyme
Q9NP55 BXGT021141 BPI fold-containing family A member 1 51297 reviewed
Q9NWM0 BXGT021232 Spermine oxidase 54498 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
P31994 BXGT023298 Low affinity immunoglobulin gamma Fc region receptor II-b 2213 reviewed Cell adhesion
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q96QC4 BXGT023878 MHC class I polypeptide-related sequence A 100507436 unreviewed
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
P20809 BXGT025043 Interleukin-11 3589 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
P25090 BXGT025102 N-formyl peptide receptor 2 2358 reviewed G-protein coupled receptor
Q96MS0 BXGT025241 Roundabout homolog 3 64221 reviewed Receptor
Q92888 BXGT026130 Rho guanine nucleotide exchange factor 1 9138 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease