Showing entry for Undylic acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0003418
Compound NameUndylic acid
Structure
FormulaC9H13N2O9P
InchiKeyDJJCXFVJDGTHFX-XVFCMESISA-N
SMILESO[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)N1C=CC(=O)NC1=O
InchiInChI=1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
IUPAC{[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
Molecular Weight324.18
Pubchem Id6030
Chembl IdCHEMBL214393
Targets of Information Source
DrugBank DB03685
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P0AA43 BXGT007206 Ribosomal small subunit pseudouridine synthase A reviewed - rsuA experimental -
Q9NWZ5 BXGT021240 Uridine-cytidine kinase-like 1 reviewed Kinase UCKL1 experimental -
P09148 BXGT006861 Galactose-1-phosphate uridylyltransferase reviewed - galT experimental -
P00469 BXGT005550 Thymidylate synthase reviewed - thyA experimental -
Q7Z4J2 BXGT017256 Putative glycosyltransferase 6 domain-containing protein 1 reviewed - GLT6D1 experimental -
P62312 BXGT011419 U6 snRNA-associated Sm-like protein LSm6 reviewed - LSM6 experimental -
Q9WZI0 BXGT022027 Uracil phosphoribosyltransferase reviewed - upp experimental -
P15291 BXGT008103 Beta-1,4-galactosyltransferase 1 reviewed Enzyme B4GALT1 experimental -
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein reviewed - ISG20 experimental -
P25971 BXGT009081 Orotidine 5'-phosphate decarboxylase reviewed - pyrF experimental -
P41007 BXGT010216 Bifunctional protein PyrR reviewed - pyrR experimental -
Q5KUI3 BXGT015465 Uracil phosphoribosyltransferase reviewed - upp experimental -
P77398 BXGT011806 Bifunctional polymyxin resistance protein ArnA reviewed - arnA experimental -
PDB U
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P0ABF6 BXGT007230 Cytidine deaminase reviewed cdd - - - - -
P00469 BXGT005550 Thymidylate synthase reviewed thyA - - - - -
P25971 BXGT009081 Orotidine 5'-phosphate decarboxylase reviewed pyrF - 460000 - - -
P08037 BXGT006717 Beta-1,4-galactosyltransferase 1 reviewed B4GALT1 - - - - -
P14769 BXGT008050 N-acetyllactosaminide alpha-1,3-galactosyltransferase reviewed GGTA1 - - - - -
P09148 BXGT006861 Galactose-1-phosphate uridylyltransferase reviewed galT - - - - -
P70881 BXGT022682 Uracil phosphoribosyltransferase reviewed upp - - - - -
O26232 BXGT004271 Orotidine 5'-phosphate decarboxylase reviewed pyrF - - - - -
P0AA43 BXGT007206 Ribosomal small subunit pseudouridine synthase A reviewed rsuA - - - - -
O26745 BXGT004277 Putative snRNP Sm-like protein reviewed MTH_649 - - - - -
O26232 BXGT004271 Orotidine 5'-phosphate decarboxylase reviewed pyrF - 200000 - - -
Q9V0Y8 BXGT021852 Putative snRNP Sm-like protein reviewed PYRAB06500 - - - - -
Q9WZI0 BXGT022027 Uracil phosphoribosyltransferase reviewed upp - - - - -
P00968 BXGT005708 Carbamoyl-phosphate synthase large chain reviewed carB - - - 9000 -
P23540 BXGT008881 Ribonuclease MC reviewed - - - - -
Q26998 BXGT013924 Uracil phosphoribosyltransferase reviewed uprt - - - - -
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein reviewed ISG20 - - - - -
Q980Q4 BXGT019874 Uracil phosphoribosyltransferase reviewed upp - - - - -
P41007 BXGT010216 Bifunctional protein PyrR reviewed pyrR - - - - -
P0A1F6 BXGT006985 Uridine phosphorylase reviewed udp - - - - -
Q9NPB1 BXGT021149 5'(3')-deoxyribonucleotidase, mitochondrial reviewed NT5M - - - - -
Q86MV5 BXGT017591 RNA editing complex protein MP57 reviewed KRET2 - - - - -
P77398 BXGT011806 Bifunctional polymyxin resistance protein ArnA reviewed arnA - - - - -
Q8U122 BXGT018867 Uridylate kinase reviewed pyrH - - - - -
P0A7E9 BXGT007113 Uridylate kinase reviewed pyrH - - - - -
Q9UXC0 BXGT021837 Exosome complex component Rrp42 reviewed rrp42 - - - - -
Q9UXC2 BXGT021838 Exosome complex component Rrp41 reviewed rrp41 - - - - -
O58462 BXGT004802 Orotidine 5'-phosphate decarboxylase reviewed pyrF - - - - -
O26232 BXGT004271 Orotidine 5'-phosphate decarboxylase reviewed pyrF - - - - -
Q9DS05 BXGT022686 Polyprotein unreviewed - - - - -
P03007 BXGT006005 DNA polymerase III subunit epsilon reviewed dnaQ - - - - -
Q12149 BXGT013230 Exosome complex exonuclease RRP6 reviewed RRP6 - - - - -
Q9M9P3 BXGT021107 UTP--glucose-1-phosphate uridylyltransferase 2 reviewed UGP2 - - - - -
Q97ZE2 BXGT019864 Uridylate kinase reviewed pyrH - - - - -
Q97ZE2 BXGT019864 Uridylate kinase reviewed pyrH - - - 14000 -
Q381M1 BXGT014337 Poly(A) polymerase, putative reviewed TUT4 - - - - -
Q8IJH3 BXGT018287 Orotidine 5'-phosphate decarboxylase unreviewed PF3D7_1023200 - - - - -
P11172 BXGT007665 Uridine 5'-monophosphate synthase reviewed UMPS - - - - -
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] reviewed SOD1 Enzyme - - - -
P49902 BXGT010758 Cytosolic purine 5'-nucleotidase reviewed NT5C2 Enzyme - - - -
P0A1R0 BXGT006988 RNA-binding protein Hfq reviewed hfq - - - - -
Q8T6J6 BXGT018775 Orotidine 5'-monophosphate decarboxylase unreviewed ompdc - - - - -
Q72JJ7 BXGT016746 Ribonuclease J reviewed rnj - - - - -
P61823 BXGT011385 Ribonuclease pancreatic reviewed RNASE1 - - - - -
P23371 BXGT008858 Poly(A) polymerase catalytic subunit reviewed PAPL - - - - -
Q48485 BXGT014748 UDP-galactopyranose mutase reviewed rfbD - - - - -
Q9Q0U9 BXGT021358 Polymerase acidic protein reviewed PA - - - - -
P16442 BXGT008227 Histo-blood group ABO system transferase reviewed ABO Enzyme - - - -
Q5SLP1 BXGT022702 Ribonuclease TTHA0252 reviewed TTHA0252 - - - - -
Q9UKV8 BXGT021752 Protein argonaute-2 reviewed AGO2 - - - 120000 -
A9IH93 BXGT001790 Lipopolysaccharides biosynthesis acetyltransferase unreviewed wlbB - - - - -
P53078 BXGT010972 Suppressor of disruption of TFIIS reviewed SDT1 - - - - -
A0A0J9WZA6 BXGT022706 UDP-glucose 6-dehydrogenase unreviewed ugd - - - - -
E9BCQ9 BXGT003168 Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative unreviewed LDBPK_160560 - - - - -
Q9KQT7 BXGT020985 Orotidine 5'-phosphate decarboxylase reviewed pyrF - - - - -
O26232 BXGT004271 Orotidine 5'-phosphate decarboxylase reviewed pyrF - - - 420000 -
C3W5S0 BXGT002458 Polymerase acidic protein unreviewed PA - - - - -
Q96662 BXGT019603 Genome polyprotein reviewed - - - - -
Q96662 BXGT019603 Genome polyprotein reviewed - - - - -
Q9D020 BXGT020254 Cytosolic 5'-nucleotidase 3A reviewed Nt5c3a - - - - -
O04379 BXGT003964 Protein argonaute 1 reviewed AGO1 - - - 980000 -
P27472 BXGT009184 Glycogen [starch] synthase isoform 2 reviewed GSY2 - - - - -
P33469 BXGT009726 Nucleoprotein reviewed N - - - - -
Q9HUM0 BXGT020606 RNA-binding protein Hfq reviewed hfq - - - - -
O57978 BXGT004774 Phosphoribosylaminoimidazole-succinocarboxamide synthase reviewed purC - - - - -
P9WJ73 BXGT012336 3'-5' exoribonuclease Rv2179c reviewed Rv2179c - - - - -
C1IFD2 BXGT022781 RNA-binding protein Hfq unreviewed hfq - - - - -
Q58830 BXGT015211 Uncharacterized protein MJ1435 reviewed MJ1435 - - - - -
H9CZL7 BXGT022891 Ribonuclease J (RNase J) unreviewed rnj - - - - -
P42982 BXGT022999 N-acetyl-alpha-D-glucosaminyl L-malate synthase reviewed bshA - - - - -
Q8B3M2 BXGT017905 Genome polyprotein unreviewed - - - - -
P49773 BXGT010741 Histidine triad nucleotide-binding protein 1 reviewed HINT1 Enzyme - - - -
Q8B3M2 BXGT017905 Genome polyprotein unreviewed - - - - -
Q5SHR1 BXGT015690 Translation initiation factor IF-1 reviewed infA - - - - -
Q5SKU2 BXGT015778 Translation initiation factor IF-3 reviewed infC - - - - -
P16442 BXGT008227 Histo-blood group ABO system transferase reviewed ABO Enzyme - - - -
A6UPF5 BXGT001508 Like-Sm ribonucleoprotein core unreviewed Mevan_0470 - - - - -
Q7TG18 BXGT017143 Genome polyprotein unreviewed - - - - -
Q7TG18 BXGT017143 Genome polyprotein unreviewed - - - - -
Q9BQ65 BXGT020107 U6 snRNA phosphodiesterase reviewed USB1 - - - - -
Q47VZ4 BXGT023686 Oligoribonuclease reviewed orn - - - - -
P21513 BXGT008657 Ribonuclease E reviewed rne - - - - -
W0TCJ5 BXGT025213 Uncharacterized protein YLR132C unreviewed KLMA_50491 - - - - -
Q06151 BXGT012858 m7GpppX diphosphatase reviewed DCS1 - - - - -
P0DTD1 BXGT023328 Replicase polyprotein 1ab reviewed rep - - - - -
Binding DB 50398699
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT004271 Orotidine 5'-phosphate decarboxylase reviewed pyrF 330000 - - -
reviewed BXGT007665 Uridine 5'-monophosphate synthase reviewed UMPS 220000 - - -
CHEMBL CHEMBL214393
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P30085 BXGT009399 UMP-CMP kinase reviewed Kinase CMPK1 Kcat '=' 81 /s
P30085 BXGT009399 UMP-CMP kinase reviewed Kinase CMPK1 Km '=' 151000 nM
P30085 BXGT009399 UMP-CMP kinase reviewed Kinase CMPK1 Kcat/Km '=' 0 /uM/s
Q15077 BXGT013533 P2Y purinoceptor 6 reviewed G-protein coupled receptor P2RY6 Activity - - -
P11172 BXGT007665 Uridine 5'-monophosphate synthase reviewed - UMPS Ki '=' 220000 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 29092 nM
P49798 BXGT010745 Regulator of G-protein signaling 4 reviewed Enzyme modulator RGS4 Potency - 37685 nM
Q8T6J6 BXGT018775 Orotidine 5'-monophosphate decarboxylase unreviewed - ompdc Ki '=' 210000 nM
O26232 BXGT004271 Orotidine 5'-phosphate decarboxylase reviewed - pyrF Ki '=' 330000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00085 Soy bean Glycine max Soy
BXGF02567 Lycium chinense Lycium chinense Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease