Showing entry for Myosin-10


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009853
Protein NameMyosin-10
Uniport IdP35580
GeneMYH10
Gene Id4628
DomainIQ; Myosin_head; Myosin_N; Myosin_tail_1
Pfam PF00612   PF00063   PF02736   PF01576  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04530 Tight junction
4. Cellular Processes 4.5 Cell motility hsa04810 Regulation of actin cytoskeleton
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05132 Salmonella infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030048 actin filament-based movement
Biological Process GO:0031032 actomyosin structure organization
Biological Process GO:0007512 adult heart development
Biological Process GO:0035904 aorta development
Biological Process GO:0007411 axon guidance
Biological Process GO:0055003 cardiac myofibril assembly
Biological Process GO:0003279 cardiac septum development
Biological Process GO:0007155 cell adhesion
Biological Process GO:0008283 cell population proliferation
Biological Process GO:0021680 cerebellar Purkinje cell layer development
Biological Process GO:0060976 coronary vasculature development
Biological Process GO:0006887 exocytosis
Biological Process GO:0021592 fourth ventricle development
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0021670 lateral ventricle development
Biological Process GO:0000281 mitotic cytokinesis
Biological Process GO:0098885 modification of postsynaptic actin cytoskeleton
Biological Process GO:0050885 neuromuscular process controlling balance
Biological Process GO:0001764 neuron migration
Biological Process GO:0007097 nuclear migration
Biological Process GO:0001778 plasma membrane repair
Biological Process GO:0050714 positive regulation of protein secretion
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0060041 retina development in camera-type eye
Biological Process GO:0006930 substrate-dependent cell migration, cell extension
Biological Process GO:0021678 third ventricle development
Biological Process GO:0055015 ventricular cardiac muscle cell development
molecular function GO:0003779 actin binding
molecular function GO:0030898 actin-dependent ATPase activity
molecular function GO:0051015 actin filament binding
molecular function GO:0043531 ADP binding
molecular function GO:0016887 ATPase activity
molecular function GO:0005524 ATP binding
molecular function GO:0005516 calmodulin binding
molecular function GO:0000146 microfilament motor activity
molecular function GO:0048027 mRNA 5'-UTR binding
molecular function GO:0035613 RNA stem-loop binding
cellular component GO:0042641 actomyosin
cellular component GO:0005903 brush border
cellular component GO:0005938 cell cortex
cellular component GO:0032154 cleavage furrow
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0043197 dendritic spine
cellular component GO:0070062 extracellular exosome
cellular component GO:0030426 growth cone
cellular component GO:0030027 lamellipodium
cellular component GO:0030496 midbody
cellular component GO:0016459 myosin complex
cellular component GO:0016460 myosin II complex
cellular component GO:0097513 myosin II filament
cellular component GO:0031594 neuromuscular junction
cellular component GO:0043025 neuronal cell body
cellular component GO:0005634 nucleus
cellular component GO:0005844 polysome
cellular component GO:0005819 spindle
cellular component GO:0001725 stress fiber
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-194315 Signaling by Rho GTPases
R-HSA-194315 Signaling by Rho GTPases
R-HSA-195258 RHO GTPase Effectors
R-HSA-195258 RHO GTPase Effectors
R-HSA-2682334 EPH-Ephrin signaling
R-HSA-373755 Semaphorin interactions
R-HSA-3928663 EPHA-mediated growth cone collapse
R-HSA-400685 Sema4D in semaphorin signaling
R-HSA-416572 Sema4D induced cell migration and growth-cone collapse
R-HSA-422475 Axon guidance
R-HSA-5625740 RHO GTPases activate PKNs
R-HSA-5625900 RHO GTPases activate CIT
R-HSA-5627117 RHO GTPases Activate ROCKs
R-HSA-5627123 RHO GTPases activate PAKs
R-HSA-5627123 RHO GTPases activate PAKs
R-HSA-9675108 Nervous system development
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003486 BXGD000197 Aortic Aneurysm Cardiovascular Diseases
C0005818 BXGD000338 Blood Platelet Disorders Hemic and Lymphatic Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0010520 BXGD000675 Cyanosis Pathological Conditions, Signs and Symptoms
C0017638 BXGD001132 Glioma Neoplasms
C0017668 BXGD001143 Focal glomerulosclerosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0020295 BXGD001372 Hydronephrosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0021053 BXGD001476 Immune System Diseases Immune System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023480 BXGD001664 Leukemia, Myelomonocytic, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0034067 BXGD002456 Pulmonary Emphysema Respiratory Tract Diseases
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0086432 BXGD003281 Hyalinosis, Segmental Glomerular Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0349639 BXGD007943 Juvenile Myelomonocytic Leukemia Neoplasms; Hemic and Lymphatic Diseases
C0476273 BXGD008986 Respiratory distress Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0521620 BXGD009150 Dilatation of ureter Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0595921 BXGD009626 Intraocular pressure disorder Eye Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0741916 BXGD010044 Cardiac defects
C0795841 BXGD010746 Jacobsen Distal 11q Deletion Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1956093 BXGD016616 Paris-Trousseau Thrombocytopenia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C2936786 BXGD018137 Aqueductal Stenosis Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0042376 Picropodophyllotoxin 414.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein