adisease

Showing entry for Cardiac defects

General Disease Information
BXGD Id	BXGD010044
Disease Name	Cardiac defects
Disease CUI Id	C0741916
MeSH Codes
Disease Class Name
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14770	BXGT004095	Homeobox protein Meis2	4212	reviewed	Enzyme
O15119	BXGT004128	T-box transcription factor TBX3	6926	reviewed	Transcription factor
O95644	BXGT005389	Nuclear factor of activated T-cells, cytoplasmic 1	4772	reviewed	Transcription factor
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P21333	BXGT008638	Filamin-A	2316	reviewed
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P22681	BXGT008795	E3 ubiquitin-protein ligase CBL	867	reviewed	Enzyme
P24468	BXGT008969	COUP transcription factor 2	7026	reviewed	Nuclear receptor
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P35580	BXGT009853	Myosin-10	4628	reviewed
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P52952	BXGT010966	Homeobox protein Nkx-2.5	1482	reviewed	Transcription factor
P78504	BXGT011844	Protein jagged-1	182	reviewed
Q02763	BXGT012667	Angiopoietin-1 receptor	7010	reviewed	Kinase
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q07889	BXGT012946	Son of sevenless homolog 1	6654	reviewed	Enzyme modulator
Q09013	BXGT013023	Myotonin-protein kinase	1760	reviewed	Kinase
Q14004	BXGT013435	Cyclin-dependent kinase 13	8621	reviewed	Kinase
Q14524	BXGT013478	Sodium channel protein type 5 subunit alpha	6331	reviewed	Ion channel
Q15303	BXGT013557	Receptor tyrosine-protein kinase erbB-4	2066	reviewed	Kinase
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q969S2	BXGT019612	Endonuclease 8-like 2	252969	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q99593	BXGT019939	T-box transcription factor TBX5	6910	reviewed	Transcription factor
Q9H4A3	BXGT020473	Serine/threonine-protein kinase WNK1	65125	reviewed	Kinase
Q9H7B4	BXGT020490	Histone-lysine N-methyltransferase SMYD3	64754	reviewed	Epigenetic regulator
Q9NNW7	BXGT021139	Thioredoxin reductase 2, mitochondrial	10587	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}