adisease

Showing entry for Infantile Spasm

General Disease Information
BXGD Id	BXGD019926
Disease Name	Infantile Spasm
Disease CUI Id	C3887898
MeSH Codes	C23 C10
Disease Class Name	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14936	BXGT004114	Peripheral plasma membrane protein CASK	8573	reviewed	Kinase
O76039	BXGT005171	Cyclin-dependent kinase-like 5	6792	reviewed	Kinase
O95363	BXGT005375	Phenylalanine--tRNA ligase, mitochondrial	10667	reviewed	Enzyme
P01031	BXGT005720	Complement C5	727	reviewed	Enzyme modulator
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08514	BXGT006781	Integrin alpha-IIb	3674	reviewed
P14867	BXGT008061	Gamma-aminobutyric acid receptor subunit alpha-1	2554	reviewed	Ion channel
P21730	BXGT008687	C5a anaphylatoxin chemotactic receptor 1	728	reviewed	G-protein coupled receptor
P28472	BXGT009260	Gamma-aminobutyric acid receptor subunit beta-3	2562	reviewed	Ion channel
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P32245	BXGT009614	Melanocortin receptor 4	4160	reviewed	G-protein coupled receptor
P34998	BXGT009781	Corticotropin-releasing factor receptor 1	1394	reviewed
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35498	BXGT009838	Sodium channel protein type 1 subunit alpha	6323	reviewed	Ion channel
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P43007	BXGT010350	Neutral amino acid transporter A	6509	reviewed	Transporter
P47870	BXGT010591	Gamma-aminobutyric acid receptor subunit beta-2	2561	reviewed	Ion channel
P48051	BXGT010611	G protein-activated inward rectifier potassium channel 2	3763	reviewed	Ion channel
P56524	BXGT011176	Histone deacetylase 4	9759	reviewed	Epigenetic regulator
P57059	BXGT011210	Serine/threonine-protein kinase SIK1	150094	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P61981	BXGT011400	14-3-3 protein gamma	7532	reviewed	Chaperone
P80404	BXGT011907	4-aminobutyrate aminotransferase, mitochondrial	18	reviewed	Enzyme
Q00604	BXGT012538	Norrin	4693	reviewed
Q01718	BXGT012609	Adrenocorticotropic hormone receptor	4158	reviewed	G-protein coupled receptor
Q05193	BXGT012810	Dynamin-1	1759	reviewed	Enzyme modulator
Q05586	BXGT012826	Glutamate receptor ionotropic, NMDA 1	2902	reviewed	Ion channel
Q12756	BXGT013261	Kinesin-like protein KIF1A	547	reviewed	Cellular structure
Q12879	BXGT013275	Glutamate receptor ionotropic, NMDA 2A	2903	reviewed	Ion channel
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q13303	BXGT013336	Voltage-gated potassium channel subunit beta-2	8514	reviewed	Ion channel
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	775	reviewed	Ion channel
Q14117	BXGT013443	Dihydropyrimidinase	1807	reviewed	Enzyme
Q14204	BXGT013456	Cytoplasmic dynein 1 heavy chain 1	1778	reviewed	Enzyme
Q7L3T8	BXGT016994	Probable proline--tRNA ligase, mitochondrial	25973	reviewed	Enzyme
Q96RE7	BXGT019725	Nucleus accumbens-associated protein 1	112939	reviewed
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	6326	reviewed	Ion channel
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q9NVS9	BXGT021228	Pyridoxine-5'-phosphate oxidase	55163	reviewed	Enzyme
Q9Y243	BXGT022214	RAC-gamma serine/threonine-protein kinase	10000	reviewed	Kinase
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}