Showing entry for Gastric inhibitory polypeptide receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010642
Protein NameGastric inhibitory polypeptide receptor
Uniport IdP48546
GeneGIPR
Gene Id2696
Domain7tm_2; HRM
Pfam PF00002   PF02793  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04024 cAMP signaling pathway
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007190 activation of adenylate cyclase activity
Biological Process GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Biological Process GO:0007166 cell surface receptor signaling pathway
Biological Process GO:0002029 desensitization of G protein-coupled receptor signaling pathway
Biological Process GO:0031018 endocrine pancreas development
Biological Process GO:0006091 generation of precursor metabolites and energy
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0043950 positive regulation of cAMP-mediated signaling
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0032024 positive regulation of insulin secretion
Biological Process GO:0050796 regulation of insulin secretion
Biological Process GO:0048678 response to axon injury
Biological Process GO:0051592 response to calcium ion
Biological Process GO:0070542 response to fatty acid
Biological Process GO:0009749 response to glucose
Biological Process GO:0007584 response to nutrient
molecular function GO:0016519 gastric inhibitory peptide receptor activity
molecular function GO:0008528 G protein-coupled peptide receptor activity
molecular function GO:0017046 peptide hormone binding
molecular function GO:0004888 transmembrane signaling receptor activity
cellular component GO:0016021 integral component of membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-372790 Signaling by GPCR
R-HSA-373080 Class B/2 (Secretin family receptors)
R-HSA-388396 GPCR downstream signalling
R-HSA-418555 G alpha (s) signalling events
R-HSA-420092 Glucagon-type ligand receptors
R-HSA-500792 GPCR ligand binding
R-HSA-5663205 Infectious disease
R-HSA-9658195 Leishmania infection
R-HSA-9660821 ADORA2B mediated anti-inflammatory cytokines production
R-HSA-9662851 Anti-inflammatory response favouring Leishmania parasite infection
R-HSA-9664433 Leishmania parasite growth and survival
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001206 BXGD000033 Acromegaly Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases
C0001430 BXGD000054 Adenoma Neoplasms
C0001622 BXGD000065 Adrenal Gland Hyperfunction Endocrine System Diseases
C0005845 BXGD000341 Blood urea nitrogen measurement
C0005893 BXGD000346 Body mass index procedure
C0005910 BXGD000349 Body Weight Pathological Conditions, Signs and Symptoms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0010481 BXGD000673 Cushing Syndrome Endocrine System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0017741 BXGD001149 Glucose tolerance test
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0202098 BXGD004070 Insulin measurement
C0205682 BXGD004105 Waist-Hip Ratio
C0206663 BXGD004225 Neuroectodermal Tumor, Primitive Neoplasms
C0206667 BXGD004228 Adrenal Cortical Adenoma Neoplasms; Endocrine System Diseases
C0206686 BXGD004241 Adrenocortical carcinoma Neoplasms; Endocrine System Diseases
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0337443 BXGD007161 Sodium measurement
C0342443 BXGD007481 Adrenal Cushing's syndrome Endocrine System Diseases
C0342495 BXGD007490 Macronodular adrenal hyperplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0346402 BXGD007823 Malignant neoplasm of adrenal cortex Neoplasms; Endocrine System Diseases
C0428568 BXGD008633 Fasting blood glucose measurement
C0455829 BXGD008859 Waist Circumference
C0518026 BXGD009069 body fat percentage (physical finding)
C0524587 BXGD009232 Mean Corpuscular Volume (result)
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0562350 BXGD009476 Hip circumference
C0578022 BXGD009541 Finding of body mass index
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684337 BXGD009796 Ewings sarcoma-primitive neuroectodermal tumor (PNET) Neoplasms
C0871470 BXGD011316 Systolic Pressure
C1257763 BXGD011803 Overnutrition Nutritional and Metabolic Diseases
C1261430 BXGD011853 Fasting blood sugar result
C1305855 BXGD012348 Body mass index
C1608408 BXGD013434 Malignant transformation
C1857451 BXGD015702 Acth-Independent Macronodular Adrenal Hyperplasia Endocrine System Diseases
C2362324 BXGD017091 Pediatric Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C4049938 BXGD021956 Physical Activity Measurement
C4728082 BXGD023886 Severe hypoglycaemia
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000076 p-Coumaroyl tartaric acid glucosidic ester 150.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein