Showing entry for Ras-related protein Rab-11A



                       
General Target Information
BXGT IdBXGT011430
Protein NameRas-related protein Rab-11A
Uniport IdP62491
GeneRAB11A
Gene Id8766
DomainRas
Pfam PF00071  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
5. Organismal Systems 5.5 Excretory system hsa04961 Endocrine and other factor-regulated calcium reabsorption
5. Organismal Systems 5.5 Excretory system hsa04962 Vasopressin-regulated water reabsorption
5. Organismal Systems 5.4 Digestive system hsa04972 Pancreatic secretion
6. Human Diseases 6.9 Infectious diseases: Viral hsa05164 Influenza A
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0150093 amyloid-beta clearance by transcytosis
Biological Process GO:0030953 astral microtubule organization
Biological Process GO:0097711 ciliary basal body-plasma membrane docking
Biological Process GO:0090150 establishment of protein localization to membrane
Biological Process GO:0072594 establishment of protein localization to organelle
Biological Process GO:0051650 establishment of vesicle localization
Biological Process GO:0006887 exocytosis
Biological Process GO:1990182 exosomal secretion
Biological Process GO:0032402 melanosome transport
Biological Process GO:0007080 mitotic metaphase plate congression
Biological Process GO:0090307 mitotic spindle assembly
Biological Process GO:0036258 multivesicular body assembly
Biological Process GO:0031175 neuron projection development
Biological Process GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane
Biological Process GO:0048227 plasma membrane to endosome transport
Biological Process GO:0045773 positive regulation of axon extension
Biological Process GO:0010634 positive regulation of epithelial cell migration
Biological Process GO:0010971 positive regulation of G2/M transition of mitotic cell cycle
Biological Process GO:1903078 positive regulation of protein localization to plasma membrane
Biological Process GO:0043687 post-translational protein modification
Biological Process GO:0072659 protein localization to plasma membrane
Biological Process GO:0032465 regulation of cytokinesis
Biological Process GO:0048169 regulation of long-term neuronal synaptic plasticity
Biological Process GO:0010796 regulation of multivesicular body size
Biological Process GO:0051223 regulation of protein transport
Biological Process GO:0060627 regulation of vesicle-mediated transport
Biological Process GO:0003091 renal water homeostasis
Biological Process GO:0016192 vesicle-mediated transport
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0008017 microtubule binding
molecular function GO:0031489 myosin V binding
molecular function GO:0019905 syntaxin binding
cellular component GO:0030424 axon
cellular component GO:0034451 centriolar satellite
cellular component GO:0032154 cleavage furrow
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:0005829 cytosol
cellular component GO:0005768 endosome
cellular component GO:0070062 extracellular exosome
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005794 Golgi apparatus
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005771 multivesicular body
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0045335 phagocytic vesicle
cellular component GO:0098837 postsynaptic recycling endosome
cellular component GO:0032991 protein-containing complex
cellular component GO:0055037 recycling endosome
cellular component GO:0055038 recycling endosome membrane
cellular component GO:0000922 spindle pole
cellular component GO:0005802 trans-Golgi network
cellular component GO:0030133 transport vesicle
cellular component GO:0031982 vesicle
Reactome
Pathway Id Pathway Name
R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane
R-HSA-1852241 Organelle biogenesis and maintenance
R-HSA-199991 Membrane Trafficking
R-HSA-199991 Membrane Trafficking
R-HSA-382551 Transport of small molecules
R-HSA-392499 Metabolism of proteins
R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins
R-HSA-445717 Aquaporin-mediated transport
R-HSA-5617833 Cilium Assembly
R-HSA-5620912 Anchoring of the basal body to the plasma membrane
R-HSA-5620916 VxPx cargo-targeting to cilium
R-HSA-5620920 Cargo trafficking to the periciliary membrane
R-HSA-5653656 Vesicle-mediated transport
R-HSA-5653656 Vesicle-mediated transport
R-HSA-597592 Post-translational protein modification
R-HSA-8854214 TBC/RABGAPs
R-HSA-8873719 RAB geranylgeranylation
R-HSA-9007101 Rab regulation of trafficking
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006413 BXGD000397 Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008149 BXGD000520 Chlamydia Infections Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014057 BXGD000880 Japanese Encephalitis Infections; Nervous System Diseases
C0014378 BXGD000912 Enterovirus Infections Infections
C0014772 BXGD000948 Red Blood Cell Count measurement
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0021831 BXGD001516 Intestinal Diseases Digestive System Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023794 BXGD001700 Lipoidosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0024523 BXGD001781 Malabsorption Syndrome Digestive System Diseases; Nutritional and Metabolic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027726 BXGD002030 Nephrotic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0028756 BXGD002083 Obesity, Morbid Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030389 BXGD002216 Parainfluenza Infections
C0035436 BXGD002550 Rheumatic Fever Infections; Musculoskeletal Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0263454 BXGD005309 Chloracne Skin and Connective Tissue Diseases
C0264490 BXGD005394 Acute respiratory failure Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Respiratory Tract Diseases
C0278764 BXGD006581 Adult Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0278879 BXGD006610 Childhood Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0282687 BXGD006826 Hemorrhagic Fever, Ebola Infections
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0341306 BXGD007401 Microvillus inclusion disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0375023 BXGD007970 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
C0392514 BXGD008051 Hereditary hemochromatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0403397 BXGD008277 Steroid-resistant nephrotic syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0518015 BXGD009068 Hemoglobin measurement
C0524587 BXGD009232 Mean Corpuscular Volume (result)
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0557874 BXGD009444 Global developmental delay
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1269955 BXGD012005 Tumor Cell Invasion
C1285654 BXGD012172 Memory performance
C1290884 BXGD012198 Inflammatory disorder Pathological Conditions, Signs and Symptoms
C1305855 BXGD012348 Body mass index
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1519346 BXGD013235 Skin Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1866636 BXGD016411 CHARCOT-MARIE-TOOTH DISEASE, TYPE 4C Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C2062441 BXGD016897 Influenza A
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363741 BXGD017100 HIV-1 infection
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3266102 BXGD018597 Steroid resistant nephrotic syndrome of childhood Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4290046 BXGD022507 trachomatis
C4316899 BXGD022710 Cystinosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C4528257 BXGD023159 Corpuscular Hemoglobin Concentration Mean
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0030612 tetraethylene glycol 194.12
BXGC0048845 Guanosine Triphosphate 522.99
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein