acompound

Showing entry for Flavones

General Compound Information
BXGC Id	BXGC0003776
Compound Name	Flavones
Structure
Formula	C15H10O2
InchiKey	VHBFFQKBGNRLFZ-UHFFFAOYSA-N
SMILES	O=C1C=C(OC2=CC=CC=C12)C1=CC=CC=C1
Inchi	InChI=1S/C15H10O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H
IUPAC	2-phenyl-4H-chromen-4-one
Molecular Weight	222.24
Pubchem Id	10680
Chembl Id	CHEMBL275638

Targets of Information Source

DrugBank

DB07776

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P0A3R9	BXGT007016	Neocarzinostatin	reviewed	-	ncsA	approved; experimental	-
P11474	BXGT007710	Steroid hormone receptor ERR1	reviewed	Nuclear receptor	ESRRA	approved; experimental	agonist
O95718	BXGT005392	Steroid hormone receptor ERR2	reviewed	Nuclear receptor	ESRRB	approved; experimental	agonist
Q16678	BXGT013656	Cytochrome P450 1B1	reviewed	Enzyme	CYP1B1	approved; experimental	-

PDB

FLN

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P0A3R9	BXGT007016	Neocarzinostatin	reviewed	ncsA	-	-	-	-	-
Q9H2K2	BXGT020454	Poly [ADP-ribose] polymerase tankyrase-2	reviewed	TNKS2	-	-	-	-	-

Binding DB

50028962

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT008644	Amine oxidase [flavin-containing] A	reviewed		MAOA	2500	-	-	-
reviewed	BXGT009172	Amine oxidase [flavin-containing] B	reviewed		MAOB	1060	-	-	-
reviewed	BXGT021247	Dipeptidyl peptidase 3	reviewed	Enzyme	DPP3	-	292500	-	-
reviewed	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	16982	-	-	-
reviewed	BXGT009016	Adenosine receptor A1	reviewed		Adora1	3311	-	-	-
reviewed	BXGT009437	Adenosine receptor A2a	reviewed		Adora2a	3467	-	-	-
reviewed	BXGT009016	Adenosine receptor A1	reviewed		Adora1	3280	-	-	-
reviewed	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	16900	-	-	-
reviewed	BXGT009437	Adenosine receptor A2a	reviewed		Adora2a	3450	-	-	-
reviewed	BXGT011846	DNA-dependent protein kinase catalytic subunit	reviewed	Kinase	PRKDC	-	>10000	-	-
reviewed	BXGT005575	Epidermal growth factor receptor	reviewed	Kinase	EGFR	-	5	-	-
reviewed	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	-	17000	-	-
reviewed	BXGT007717	Aromatase	reviewed	Enzyme	CYP19A1	-	8000	-	-
reviewed	BXGT007552	Androgen receptor	reviewed	Nuclear receptor	AR	-	5900	-	-
reviewed	BXGT007520	Calmodulin-1	reviewed		CALM1	-	102280	-	-
reviewed	BXGT024595	Calmodulin-3	reviewed		CALM3	-	102280	-	-
reviewed	BXGT007521	Calmodulin-2	reviewed		CALM2	-	102280	-	-
reviewed	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	-	26000	-	-
reviewed	BXGT009242	Dihydroorotate dehydrogenase (fumarate)	reviewed		URA1	-	>10000	-	-
reviewed	BXGT007717	Aromatase	reviewed	Enzyme	CYP19A1	-	8	-	-
reviewed	BXGT004601	Carbonic anhydrase 12	reviewed		CA12	7330	-	-	-
reviewed	BXGT005689	Carbonic anhydrase 1	reviewed		CA1	1880	-	-	-
reviewed	BXGT005690	Carbonic anhydrase 2	reviewed		CA2	8710	-	-	-
reviewed	BXGT005690	Carbonic anhydrase 2	reviewed		CA2	8800	-	-	-
reviewed	BXGT013670	Carbonic anhydrase 9	reviewed		CA9	4130	-	-	-
reviewed	BXGT013670	Carbonic anhydrase 9	reviewed		CA9	4220	-	-	-
reviewed	BXGT004601	Carbonic anhydrase 12	reviewed		CA12	7220	-	-	-
reviewed	BXGT005689	Carbonic anhydrase 1	reviewed		CA1	1890	-	-	-
reviewed	BXGT008096	Androgen receptor	reviewed		Ar	-	77624.71	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	-	33884	-
reviewed	BXGT006934	Poly [ADP-ribose] polymerase 1	reviewed		PARP1	-	1400	-	-
reviewed	BXGT020454	Poly [ADP-ribose] polymerase tankyrase-2	reviewed		TNKS2	-	140	-	-
reviewed	BXGT005369	Poly [ADP-ribose] polymerase tankyrase-1	reviewed		TNKS	-	320	-	-
reviewed	BXGT007717	Aromatase	reviewed	Enzyme	CYP19A1	-	10000	-	-

CHEMBL

CHEMBL275638

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Potency	'='	12589	nM
Q96QE3	BXGT019718	ATPase family AAA domain-containing protein 5	reviewed	-	ATAD5	Potency	-	20587	nM
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	730	nM
P25099	BXGT009016	Adenosine receptor A1	reviewed	-	Adora1	Ki	'='	3280	nM
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	reviewed	Enzyme	NFE2L2	Potency	-	5448	nM
Q16445	BXGT013629	Gamma-aminobutyric acid receptor subunit alpha-6	reviewed	Ion channel	GABRA6	Ki	'='	1000	nM
P31644	BXGT009557	Gamma-aminobutyric acid receptor subunit alpha-5	reviewed	Ion channel	GABRA5	Ki	'='	1000	nM
P47869	BXGT010590	Gamma-aminobutyric acid receptor subunit alpha-2	reviewed	Ion channel	GABRA2	Ki	'='	1000	nM
P78334	BXGT011834	Gamma-aminobutyric acid receptor subunit epsilon	reviewed	Ion channel	GABRE	Ki	'='	1000	nM
P18505	BXGT008409	Gamma-aminobutyric acid receptor subunit beta-1	reviewed	Ion channel	GABRB1	Ki	'='	1000	nM
Q8N1C3	BXGT018498	Gamma-aminobutyric acid receptor subunit gamma-1	reviewed	Ion channel	GABRG1	Ki	'='	1000	nM
O14764	BXGT004094	Gamma-aminobutyric acid receptor subunit delta	reviewed	Ion channel	GABRD	Ki	'='	1000	nM
O00591	BXGT003939	Gamma-aminobutyric acid receptor subunit pi	reviewed	Ion channel	GABRP	Ki	'='	1000	nM
P34903	BXGT009769	Gamma-aminobutyric acid receptor subunit alpha-3	reviewed	Ion channel	GABRA3	Ki	'='	1000	nM
Q9UN88	BXGT021783	Gamma-aminobutyric acid receptor subunit theta	reviewed	Ion channel	GABRQ	Ki	'='	1000	nM
Q99928	BXGT019975	Gamma-aminobutyric acid receptor subunit gamma-3	reviewed	Ion channel	GABRG3	Ki	'='	1000	nM
P48169	BXGT010622	Gamma-aminobutyric acid receptor subunit alpha-4	reviewed	Ion channel	GABRA4	Ki	'='	1000	nM
P28472	BXGT009260	Gamma-aminobutyric acid receptor subunit beta-3	reviewed	Ion channel	GABRB3	Ki	'='	1000	nM
P18507	BXGT008411	Gamma-aminobutyric acid receptor subunit gamma-2	reviewed	Ion channel	GABRG2	Ki	'='	1000	nM
P47870	BXGT010591	Gamma-aminobutyric acid receptor subunit beta-2	reviewed	Ion channel	GABRB2	Ki	'='	1000	nM
P14867	BXGT008061	Gamma-aminobutyric acid receptor subunit alpha-1	reviewed	Ion channel	GABRA1	Ki	'='	1000	nM
P04150	BXGT006154	Glucocorticoid receptor	reviewed	Nuclear receptor	NR3C1	EC150	'='	26	uM
P09874	BXGT006934	Poly [ADP-ribose] polymerase 1	reviewed	-	PARP1	IC50	'='	1400	nM
P52270	BXGT010924	Triosephosphate isomerase, glycosomal	reviewed	-		Inhibition	'='	83	%
P14061	BXGT007979	Estradiol 17-beta-dehydrogenase 1	reviewed	Enzyme	HSD17B1	IC50	-	-	-
Q12791	BXGT013264	Calcium-activated potassium channel subunit alpha-1	reviewed	Ion channel	KCNMA1	Control	'='	102	%
Q08493	BXGT012987	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	reviewed	-	PDE4C	Inhibition	'='	50	%
Q07343	BXGT012926	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	reviewed	-	PDE4B	Inhibition	'='	50	%
Q08499	BXGT012988	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	reviewed	-	PDE4D	Inhibition	'='	50	%
P27815	BXGT009208	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	reviewed	-	PDE4A	Inhibition	'='	50	%
P51151	BXGT010837	Ras-related protein Rab-9A	reviewed	-	RAB9A	Potency	'='	3162	nM
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	reviewed	Enzyme	NFE2L2	Potency	-	21689	nM
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	reviewed	Enzyme	NFE2L2	Potency	-	18833	nM
P04150	BXGT006154	Glucocorticoid receptor	reviewed	Nuclear receptor	NR3C1	Activity	-	-	-
P37059	BXGT009957	Estradiol 17-beta-dehydrogenase 2	reviewed	Enzyme	HSD17B2	Activity	'='	63	%
P00918	BXGT005690	Carbonic anhydrase 2	reviewed	-	CA2	Ki	'='	8710	nM
Q16790	BXGT013670	Carbonic anhydrase 9	reviewed	-	CA9	Ki	'='	4220	nM
P10275	BXGT007552	Androgen receptor	reviewed	Nuclear receptor	AR	Ratio IC50	'='	6	-
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	reviewed	Enzyme	NFE2L2	Potency	-	31622	nM
P78527	BXGT011846	DNA-dependent protein kinase catalytic subunit	reviewed	Kinase	PRKDC	IC50	'>'	10000	nM
Q9ES14	BXGT020314	Gamma-aminobutyric acid receptor subunit epsilon	reviewed	-	Gabre	Ki	'='	4200	nM
Q91ZM7	BXGT019327	GABA theta subunit	unreviewed	-	Gabrq	Ki	'='	4200	nM
P63138	BXGT011502	Gamma-aminobutyric acid receptor subunit beta-2	reviewed	-	Gabrb2	Ki	'='	4200	nM
P63079	BXGT011491	Gamma-aminobutyric acid receptor subunit beta-3	reviewed	-	Gabrb3	Ki	'='	4200	nM
P62813	BXGT011460	Gamma-aminobutyric acid receptor subunit alpha-1	reviewed	-	Gabra1	Ki	'='	4200	nM
P30191	BXGT009410	Gamma-aminobutyric acid receptor subunit alpha-6	reviewed	-	Gabra6	Ki	'='	4200	nM
P28473	BXGT009261	Gamma-aminobutyric acid receptor subunit gamma-3	reviewed	-	Gabrg3	Ki	'='	4200	nM
P28471	BXGT009259	Gamma-aminobutyric acid receptor subunit alpha-4	reviewed	-	Gabra4	Ki	'='	4200	nM
P23576	BXGT008885	Gamma-aminobutyric acid receptor subunit alpha-2	reviewed	-	Gabra2	Ki	'='	4200	nM
P23574	BXGT008884	Gamma-aminobutyric acid receptor subunit gamma-1	reviewed	-	Gabrg1	Ki	'='	4200	nM
P20236	BXGT008551	Gamma-aminobutyric acid receptor subunit alpha-3	reviewed	-	Gabra3	Ki	'='	4200	nM
P19969	BXGT008536	Gamma-aminobutyric acid receptor subunit alpha-5	reviewed	-	Gabra5	Ki	'='	4200	nM
P18508	BXGT008412	Gamma-aminobutyric acid receptor subunit gamma-2	reviewed	-	Gabrg2	Ki	'='	4200	nM
P18506	BXGT008410	Gamma-aminobutyric acid receptor subunit delta	reviewed	-	Gabrd	Ki	'='	4200	nM
P15431	BXGT008122	Gamma-aminobutyric acid receptor subunit beta-1	reviewed	-	Gabrb1	Ki	'='	4200	nM
O09028	BXGT004049	Gamma-aminobutyric acid receptor subunit pi	reviewed	-	Gabrp	Ki	'='	4200	nM
Q54A96	BXGT015050	Dihydroorotate dehydrogenase	unreviewed	-	dhod	IC50	'>'	10000	nM
P25099	BXGT009016	Adenosine receptor A1	reviewed	-	Adora1	pKi(uM)	'='	0	-
O15118	BXGT004127	NPC intracellular cholesterol transporter 1	reviewed	Transporter	NPC1	Potency	'='	5623	nM
Q965D6	BXGT019601	3-oxoacyl-acyl-carrier protein reductase	unreviewed	-	fabG	Activity	-	-	-
Q16445	BXGT013629	Gamma-aminobutyric acid receptor subunit alpha-6	reviewed	Ion channel	GABRA6	Ki	'='	17	nM
P31644	BXGT009557	Gamma-aminobutyric acid receptor subunit alpha-5	reviewed	Ion channel	GABRA5	Ki	'='	17	nM
P47869	BXGT010590	Gamma-aminobutyric acid receptor subunit alpha-2	reviewed	Ion channel	GABRA2	Ki	'='	17	nM
P78334	BXGT011834	Gamma-aminobutyric acid receptor subunit epsilon	reviewed	Ion channel	GABRE	Ki	'='	17	nM
P18505	BXGT008409	Gamma-aminobutyric acid receptor subunit beta-1	reviewed	Ion channel	GABRB1	Ki	'='	17	nM
Q8N1C3	BXGT018498	Gamma-aminobutyric acid receptor subunit gamma-1	reviewed	Ion channel	GABRG1	Ki	'='	17	nM
O14764	BXGT004094	Gamma-aminobutyric acid receptor subunit delta	reviewed	Ion channel	GABRD	Ki	'='	17	nM
O00591	BXGT003939	Gamma-aminobutyric acid receptor subunit pi	reviewed	Ion channel	GABRP	Ki	'='	17	nM
P34903	BXGT009769	Gamma-aminobutyric acid receptor subunit alpha-3	reviewed	Ion channel	GABRA3	Ki	'='	17	nM
Q9UN88	BXGT021783	Gamma-aminobutyric acid receptor subunit theta	reviewed	Ion channel	GABRQ	Ki	'='	17	nM
Q99928	BXGT019975	Gamma-aminobutyric acid receptor subunit gamma-3	reviewed	Ion channel	GABRG3	Ki	'='	17	nM
P48169	BXGT010622	Gamma-aminobutyric acid receptor subunit alpha-4	reviewed	Ion channel	GABRA4	Ki	'='	17	nM
P28472	BXGT009260	Gamma-aminobutyric acid receptor subunit beta-3	reviewed	Ion channel	GABRB3	Ki	'='	17	nM
P18507	BXGT008411	Gamma-aminobutyric acid receptor subunit gamma-2	reviewed	Ion channel	GABRG2	Ki	'='	17	nM
P47870	BXGT010591	Gamma-aminobutyric acid receptor subunit beta-2	reviewed	Ion channel	GABRB2	Ki	'='	17	nM
P14867	BXGT008061	Gamma-aminobutyric acid receptor subunit alpha-1	reviewed	Ion channel	GABRA1	Ki	'='	17	nM
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	IC50	'='	17000	nM
P52270	BXGT010924	Triosephosphate isomerase, glycosomal	reviewed	-		Inhibition	'='	52	%
P37059	BXGT009957	Estradiol 17-beta-dehydrogenase 2	reviewed	Enzyme	HSD17B2	IC50	-	-	-
P0DP23	BXGT007520	Calmodulin-1	reviewed	-	CALM1	Inhibition	-	-	-
P04637	BXGT006243	Cellular tumor antigen p53	reviewed	Transcription factor	TP53	Potency	'='	5	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Kd	'='	33884	nM
P35869	BXGT009877	Aryl hydrocarbon receptor	reviewed	Transcription factor	AHR	Potency	-	50118	nM
Q9ES14	BXGT020314	Gamma-aminobutyric acid receptor subunit epsilon	reviewed	-	Gabre	GABA ratio	'='	1	-
Q91ZM7	BXGT019327	GABA theta subunit	unreviewed	-	Gabrq	GABA ratio	'='	1	-
P63138	BXGT011502	Gamma-aminobutyric acid receptor subunit beta-2	reviewed	-	Gabrb2	GABA ratio	'='	1	-
P63079	BXGT011491	Gamma-aminobutyric acid receptor subunit beta-3	reviewed	-	Gabrb3	GABA ratio	'='	1	-
P62813	BXGT011460	Gamma-aminobutyric acid receptor subunit alpha-1	reviewed	-	Gabra1	GABA ratio	'='	1	-
P30191	BXGT009410	Gamma-aminobutyric acid receptor subunit alpha-6	reviewed	-	Gabra6	GABA ratio	'='	1	-
P28473	BXGT009261	Gamma-aminobutyric acid receptor subunit gamma-3	reviewed	-	Gabrg3	GABA ratio	'='	1	-
P28471	BXGT009259	Gamma-aminobutyric acid receptor subunit alpha-4	reviewed	-	Gabra4	GABA ratio	'='	1	-
P23576	BXGT008885	Gamma-aminobutyric acid receptor subunit alpha-2	reviewed	-	Gabra2	GABA ratio	'='	1	-
P23574	BXGT008884	Gamma-aminobutyric acid receptor subunit gamma-1	reviewed	-	Gabrg1	GABA ratio	'='	1	-
P20236	BXGT008551	Gamma-aminobutyric acid receptor subunit alpha-3	reviewed	-	Gabra3	GABA ratio	'='	1	-
P19969	BXGT008536	Gamma-aminobutyric acid receptor subunit alpha-5	reviewed	-	Gabra5	GABA ratio	'='	1	-
P18508	BXGT008412	Gamma-aminobutyric acid receptor subunit gamma-2	reviewed	-	Gabrg2	GABA ratio	'='	1	-
P18506	BXGT008410	Gamma-aminobutyric acid receptor subunit delta	reviewed	-	Gabrd	GABA ratio	'='	1	-
P15431	BXGT008122	Gamma-aminobutyric acid receptor subunit beta-1	reviewed	-	Gabrb1	GABA ratio	'='	1	-
O09028	BXGT004049	Gamma-aminobutyric acid receptor subunit pi	reviewed	-	Gabrp	GABA ratio	'='	1	-
P83916	BXGT012025	Chromobox protein homolog 1	reviewed	Epigenetic regulator	CBX1	Potency	-	3981	nM
P0DP23	BXGT007520	Calmodulin-1	reviewed	-	CALM1	IC50	'='	102280	nM
P28272	BXGT009242	Dihydroorotate dehydrogenase (fumarate)	reviewed	-	URA1	IC50	'>'	10000	nM
P08659	BXGT006805	Luciferin 4-monooxygenase	reviewed	-		Potency	-	21331	nM
P10275	BXGT007552	Androgen receptor	reviewed	Nuclear receptor	AR	IC50	'='	5900	nM
Q16637	BXGT013646	Survival motor neuron protein	reviewed	Epigenetic regulator	SMN1	Potency	'='	14125	nM
P0DMS8	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	pKi(uM)	'='	-1	-
P35869	BXGT009877	Aryl hydrocarbon receptor	reviewed	Transcription factor	AHR	Potency	-	44668	nM
Q05769	BXGT012834	Prostaglandin G/H synthase 2	reviewed	-	Ptgs2	Inhibition	'='	92	%
O95271	BXGT005369	Poly [ADP-ribose] polymerase tankyrase-1	reviewed	-	TNKS	IC50	'='	330	nM
Q965D7	BXGT019602	Beta-hydroxyacyl-ACP dehydratase	unreviewed	-	fabZ	Activity	-	-	-
P21397	BXGT008644	Amine oxidase [flavin-containing] A	reviewed	-	MAOA	Inhibition	'='	40	%
P04150	BXGT006154	Glucocorticoid receptor	reviewed	Nuclear receptor	NR3C1	Potency	-	35481	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	43277	nM
P0DMS8	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	Ki	'='	16900	nM
Q08493	BXGT012987	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	reviewed	-	PDE4C	Activity	'='	3	pmol
Q07343	BXGT012926	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	reviewed	-	PDE4B	Activity	'='	3	pmol
Q08499	BXGT012988	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	reviewed	-	PDE4D	Activity	'='	3	pmol
P27815	BXGT009208	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	reviewed	-	PDE4A	Activity	'='	3	pmol
P19793	BXGT008515	Retinoic acid receptor RXR-alpha	reviewed	Nuclear receptor	RXRA	Potency	-	3162	nM
P30543	BXGT009437	Adenosine receptor A2a	reviewed	-	Adora2a	Ki	'='	3450	nM
P29276	BXGT009329	Adenosine receptor A2b	reviewed	-	Adora2b	Ki	'='	3450	nM
P28647	BXGT009282	Adenosine receptor A3	reviewed	-	Adora3	Ratio	'='	0	-
P25099	BXGT009016	Adenosine receptor A1	reviewed	-	Adora1	Ratio	'='	0	-
P30543	BXGT009437	Adenosine receptor A2a	reviewed	-	Adora2a	Ki	'='	3450	nM
P43220	BXGT010367	Glucagon-like peptide 1 receptor	reviewed	G-protein coupled receptor	GLP1R	Potency	-	12589	nM
P28845	BXGT009297	Corticosteroid 11-beta-dehydrogenase isozyme 1	reviewed	-	HSD11B1	Inhibition	'='	16	%
Q9R1A7	BXGT021413	Nuclear receptor subfamily 1 group I member 2	reviewed	-	Nr1i2	Potency	-	50118	nM
P43220	BXGT010367	Glucagon-like peptide 1 receptor	reviewed	G-protein coupled receptor	GLP1R	Potency	-	19952	nM
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	reviewed	-	HPGD	Potency	'='	8912	nM
Q9ES14	BXGT020314	Gamma-aminobutyric acid receptor subunit epsilon	reviewed	-	Gabre	Ki	'='	1000	nM
Q91ZM7	BXGT019327	GABA theta subunit	unreviewed	-	Gabrq	Ki	'='	1000	nM
P63138	BXGT011502	Gamma-aminobutyric acid receptor subunit beta-2	reviewed	-	Gabrb2	Ki	'='	1000	nM
P63079	BXGT011491	Gamma-aminobutyric acid receptor subunit beta-3	reviewed	-	Gabrb3	Ki	'='	1000	nM
P62813	BXGT011460	Gamma-aminobutyric acid receptor subunit alpha-1	reviewed	-	Gabra1	Ki	'='	1000	nM
P30191	BXGT009410	Gamma-aminobutyric acid receptor subunit alpha-6	reviewed	-	Gabra6	Ki	'='	1000	nM
P28473	BXGT009261	Gamma-aminobutyric acid receptor subunit gamma-3	reviewed	-	Gabrg3	Ki	'='	1000	nM
P28471	BXGT009259	Gamma-aminobutyric acid receptor subunit alpha-4	reviewed	-	Gabra4	Ki	'='	1000	nM
P23576	BXGT008885	Gamma-aminobutyric acid receptor subunit alpha-2	reviewed	-	Gabra2	Ki	'='	1000	nM
P23574	BXGT008884	Gamma-aminobutyric acid receptor subunit gamma-1	reviewed	-	Gabrg1	Ki	'='	1000	nM
P20236	BXGT008551	Gamma-aminobutyric acid receptor subunit alpha-3	reviewed	-	Gabra3	Ki	'='	1000	nM
P19969	BXGT008536	Gamma-aminobutyric acid receptor subunit alpha-5	reviewed	-	Gabra5	Ki	'='	1000	nM
P18508	BXGT008412	Gamma-aminobutyric acid receptor subunit gamma-2	reviewed	-	Gabrg2	Ki	'='	1000	nM
P18506	BXGT008410	Gamma-aminobutyric acid receptor subunit delta	reviewed	-	Gabrd	Ki	'='	1000	nM
P15431	BXGT008122	Gamma-aminobutyric acid receptor subunit beta-1	reviewed	-	Gabrb1	Ki	'='	1000	nM
O09028	BXGT004049	Gamma-aminobutyric acid receptor subunit pi	reviewed	-	Gabrp	Ki	'='	1000	nM
P15207	BXGT008096	Androgen receptor	reviewed	-	Ar	IC50	'='	77624	nM
P00533	BXGT005575	Epidermal growth factor receptor	reviewed	Kinase	EGFR	IC50	'='	50	ug.mL-1
P51449	BXGT010846	Nuclear receptor ROR-gamma	reviewed	Nuclear receptor	RORC	Potency	-	1496	nM
Q9H2K2	BXGT020454	Poly [ADP-ribose] polymerase tankyrase-2	reviewed	-	TNKS2	IC50	'='	147	nM
P03372	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	Potency	-	1258	nM
P15144	BXGT008087	Aminopeptidase N	reviewed	Enzyme	ANPEP	Inhibition	'='	5	%
O95271	BXGT005369	Poly [ADP-ribose] polymerase tankyrase-1	reviewed	-	TNKS	IC50	'='	323	nM
P11388	BXGT007697	DNA topoisomerase 2-alpha	reviewed	-	TOP2A	Activity	-	-	-
P19793	BXGT008515	Retinoic acid receptor RXR-alpha	reviewed	Nuclear receptor	RXRA	Potency	-	22387	nM
Q16790	BXGT013670	Carbonic anhydrase 9	reviewed	-	CA9	Ki	'='	4130	nM
P0DP23	BXGT007520	Calmodulin-1	reviewed	-	CALM1	Ratio IC50	'='	0	-
P11511	BXGT007717	Aromatase	reviewed	Enzyme	CYP19A1	IC50	'='	8000	nM
Q965D5	BXGT019600	Enoyl-acyl-carrier protein reductase	unreviewed	-	fabI	Activity	-	-	-
P03126	BXGT006024	Protein E6	reviewed	-	E6	Inhibition	-	-	-
Q03181	BXGT012701	Peroxisome proliferator-activated receptor delta	reviewed	Nuclear receptor	PPARD	Potency	-	3548	nM
P30543	BXGT009437	Adenosine receptor A2a	reviewed	-	Adora2a	pKi(uM)	'='	0	-
P11511	BXGT007717	Aromatase	reviewed	Enzyme	CYP19A1	IC50	'='	8	nM
Q9R1A7	BXGT021413	Nuclear receptor subfamily 1 group I member 2	reviewed	-	Nr1i2	Potency	-	15848	nM
P10828	BXGT007624	Thyroid hormone receptor beta	reviewed	Nuclear receptor	THRB	Potency	-	12589	nM
P27487	BXGT009187	Dipeptidyl peptidase 4	reviewed	Enzyme	DPP4	IC50	'='	170	nM
P08659	BXGT006805	Luciferin 4-monooxygenase	reviewed	-		Potency	-	20923	nM
P00915	BXGT005689	Carbonic anhydrase 1	reviewed	-	CA1	Ki	'='	1890	nM
P10145	BXGT007542	Interleukin-8	reviewed	Signaling	CXCL8	Potency	-	74978	nM
P00918	BXGT005690	Carbonic anhydrase 2	reviewed	-	CA2	Ki	'='	8800	nM
P80457	BXGT011911	Xanthine dehydrogenase/oxidase	reviewed	-	XDH	Inhibition	'='	15	%
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	IC50	'='	26000	nM
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	103	nM
P09874	BXGT006934	Poly [ADP-ribose] polymerase 1	reviewed	-	PARP1	IC50	'='	1380	nM
Q9H2K2	BXGT020454	Poly [ADP-ribose] polymerase tankyrase-2	reviewed	-	TNKS2	IC50	'='	140	nM
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	reviewed	Enzyme	NFE2L2	Potency	-	4609	nM
P10275	BXGT007552	Androgen receptor	reviewed	Nuclear receptor	AR	EC150	'='	26	uM
P14061	BXGT007979	Estradiol 17-beta-dehydrogenase 1	reviewed	Enzyme	HSD17B1	Activity	'='	94	%
Q96QE3	BXGT019718	ATPase family AAA domain-containing protein 5	reviewed	-	ATAD5	Potency	-	14575	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	68589	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	29092	nM
P27338	BXGT009172	Amine oxidase [flavin-containing] B	reviewed	-	MAOB	Inhibition	-	-	-
P04150	BXGT006154	Glucocorticoid receptor	reviewed	Nuclear receptor	NR3C1	Potency	-	14125	nM
P00915	BXGT005689	Carbonic anhydrase 1	reviewed	-	CA1	Ki	'='	1880	nM
O43570	BXGT004601	Carbonic anhydrase 12	reviewed	-	CA12	Ki	'='	7220	nM
O43570	BXGT004601	Carbonic anhydrase 12	reviewed	-	CA12	Ki	'='	7330	nM
Q15118	BXGT013540	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	reviewed	Kinase	PDK1	Inhibition	'='	-1	%
P09917	BXGT006941	Arachidonate 5-lipoxygenase	reviewed	Enzyme	ALOX5	Inhibition	'<'	50	%
P11511	BXGT007717	Aromatase	reviewed	Enzyme	CYP19A1	IC50	'='	10000	nM
O95271	BXGT005369	Poly [ADP-ribose] polymerase tankyrase-1	reviewed	-	TNKS	IC50	'='	320	nM
Q16678	BXGT013656	Cytochrome P450 1B1	reviewed	Enzyme	CYP1B1	IC50	'='	600	nM
Q15118	BXGT013540	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	reviewed	Kinase	PDK1	Inhibition	-	-	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00013	Dill	Anethum graveolens	Herbs and Spices
BXGF00046	Roman camomile	Chamaemelum nobile	Herbs and Spices
BXGF00135	Date	Phoenix dactylifera	Fruits
BXGF00151	Pomegranate	Punica granatum	Fruits
BXGF00159	Rosemary	Rosmarinus officinalis	Herbs and Spices
BXGF00352	Japanese chestnut	Castanea crenata	Nuts
BXGF00502	Feijoa	Feijoa sellowiana	Fruits
BXGF01003	Carpobrotus edulis	Carpobrotus edulis	Medicinal Plant
BXGF01062	Asplenium normale	Asplenium normale	Others
BXGF01137	Centrolobium tomentosum	Centrolobium tomentosum	Others
BXGF01201	Psilostrophe cooperi	Psilostrophe cooperi	Others
BXGF01305	Trifolium alexandrinum	Trifolium alexandrinum	Medicinal Plant
BXGF01507	Sideritis tragoriganum	Sideritis tragoriganum	Others
BXGF01778	Solanum jamaicense	Solanum jamaicense	Others
BXGF01895	Lippia carviodora	Lippia carviodora	Medicinal Plant
BXGF01912	Ceratophyllum submersum	Ceratophyllum submersum	Others
BXGF01936	Brucea javanica	Brucea javanica	Medicinal Plant
BXGF01971	Myrica nana	Myrica nana	Others
BXGF02061	Dracocephalum kotschyi	Dracocephalum kotschyi	Medicinal Plant
BXGF02268	Ginkgo semen	Ginkgo semen	Others
BXGF02518	Schkuhria multiflora	Schkuhria multiflora	Others
BXGF03734	Anthocleista grandiflora	Anthocleista grandiflora	Medicinal Plant
BXGF03743	Helleborus caucasicus	Helleborus caucasicus	Others
BXGF03758	Lespedeza homoloba	Lespedeza homoloba	Medicinal Plant
BXGF03780	Lolium perenne	Lolium perenne	Medicinal Plant
BXGF03793	Hypoestes serpens	Hypoestes serpens	Medicinal Plant
BXGF03806	Primula farinosa	Primula farinosa	Others
BXGF04691	Oroxylum indicum	Oroxylum indicum	Medicinal Plant
BXGF04909	Hippophae fructus	Hippophae fructus	Others
BXGF04964	Chrysanthemum morifolium	Chrysanthemum morifolium	Medicinal Plant
BXGF05041	Desmodium styracifolium	Desmodium styracifolium	Medicinal Plant
BXGF05079	Swertia hickinii	Swertia hickinii	Others
BXGF05936	Commelina communis	Commelina communis	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}