Showing entry for ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013202
Protein NameADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
Uniport IdQ10588
GeneBST1
Gene Id683
DomainRib_hydrolayse
Pfam PF02267  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00760 Nicotinate and nicotinamide metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
5. Organismal Systems 5.4 Digestive system hsa04970 Salivary secretion
5. Organismal Systems 5.4 Digestive system hsa04972 Pancreatic secretion
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006959 humoral immune response
Biological Process GO:0019674 NAD metabolic process
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0030890 positive regulation of B cell proliferation
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0032956 regulation of actin cytoskeleton organization
Biological Process GO:0050848 regulation of calcium-mediated signaling
Biological Process GO:0001952 regulation of cell-matrix adhesion
Biological Process GO:0002691 regulation of cellular extravasation
Biological Process GO:0050727 regulation of inflammatory response
Biological Process GO:2001044 regulation of integrin-mediated signaling pathway
Biological Process GO:0090022 regulation of neutrophil chemotaxis
Biological Process GO:0050730 regulation of peptidyl-tyrosine phosphorylation
Biological Process GO:0090322 regulation of superoxide metabolic process
Biological Process GO:0007165 signal transduction
molecular function GO:0061811 ADP-ribosyl cyclase activity
molecular function GO:0061812 cyclic ADP-ribose hydrolase
molecular function GO:0050135 NAD(P)+ nucleosidase activity
molecular function GO:0003953 NAD+ nucleosidase activity
molecular function GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating
molecular function GO:0016849 phosphorus-oxygen lyase activity
molecular function GO:0016740 transferase activity
cellular component GO:0031225 anchored component of membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0019898 extrinsic component of membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0035579 specific granule membrane
cellular component GO:0001931 uropod
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-163125 Post-translational modification: synthesis of GPI-anchored proteins
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-196807 Nicotinate metabolism
R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
R-HSA-196854 Metabolism of vitamins and cofactors
R-HSA-392499 Metabolism of proteins
R-HSA-597592 Post-translational protein modification
R-HSA-6798695 Neutrophil degranulation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024790 BXGD001804 Paroxysmal nocturnal hemoglobinuria Hemic and Lymphatic Diseases
C0025500 BXGD001874 Mesothelioma Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0032227 BXGD002336 Pleural effusion disorder Respiratory Tract Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0041326 BXGD002915 Pleural Tuberculosis Infections; Respiratory Tract Diseases
C0162534 BXGD003953 Prion Diseases Infections; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0233401 BXGD004575 Psychiatric symptom
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0345967 BXGD007756 Malignant mesothelioma Neoplasms; Respiratory Tract Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0524528 BXGD009229 Pervasive Development Disorder Mental Disorders
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1377913 BXGD012929 Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C2985280 BXGD018223 Blood Protein Measurement
C4511452 BXGD023002 Sporadic Parkinson disease Nervous System Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0006125 Nicotinamide 122.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein